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WT-1 Mutation Detection - PCR Test

The WT-1 Mutation Detection - PCR Test is a genetic test that screens for mutations in the WT1 gene. WT1 gene mutations are associated with several types of diseases, most notably Wilms tumor, a rare kidney cancer that primarily affects children.

This test uses Polymerase Chain Reaction (PCR) technology to amplify and detect specific segments of DNA in your blood sample, allowing for the identification of alterations in the WT1 gene. Changes in this gene can lead to abnormal protein function and cause diseases like Wilms tumor, Denys-Drash syndrome, and Frasier syndrome.

  • Test NameWT-1 Mutation Detection - PCR Test
  • Sample TypeBlood
  • Preparations RequiredNo special preparation is necessary for this test. The sample can be collected at any time of day.
  • Report Time10 days
Why is the WT-1 Mutation Detection - PCR Test important?

The test is essential for early detection of diseases associated with WT1 gene mutations, such as certain types of kidney disease and cancer, enabling timely intervention and treatment.

Is fasting required for this test?

No, fasting is not required for this test.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

A blood sample is used for this test.

If there's a history of kidney disease, kidney cancer, or related syndromes in your family, or if your child has symptoms of these conditions, you should consider this test.

The test checks for mutations in the WT1 gene, which is associated with the development of several diseases when altered.

This test is typically only done once, as a diagnostic tool, unless your healthcare provider suggests otherwise.

Normal results would show no mutations in the WT1 gene.

There are no specific precautions you need to take before this test.

Modifiable Factors: There are no modifiable factors as this is a genetic test and the results are based on your genes. Nonmodifiable Factors: Family history of diseases associated with WT1 mutations.

If your test results show a WT1 gene mutation, consult with your healthcare provider or a genetic counselor for guidance on the next steps.

You should consult a genetic counselor or a specialist who deals with the condition associated with the specific mutation, such as a nephrologist for kidney-related issues or an oncologist for cancer-related concerns.

No, there is no specific preparation required for this test.

No, medication does not typically affect the results of this genetic test.

While gene mutations themselves can't be corrected, the diseases they cause can often be treated or managed. It's important to discuss this with your healthcare provider.

Yes, some WT-1 gene mutations can be inherited. It's advisable to seek genetic counseling if you're planning a family and have a known WT-1 mutation.

Understanding if you have a WT-1 mutation can be a critical component of your health journey. It enables early intervention and appropriate management of associated diseases. Always remember that if you have a WT-1 mutation, it's vital to consult with a specialist for comprehensive management and potential treatment options.

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