Lab Test

Lung Cancer Panel 1 Complete Molecular

Lung cancer, specifically non-small cell lung cancer (NSCLC), often involves various genetic changes that contribute to the development and progression of the disease. Identification of these changes is critical for determining the most effective treatment approach, as some therapies target specific mutations. The Lung Cancer Panel 1 Complete Molecular is a comprehensive test designed to detect several of these genetic alterations, providing valuable information to guide treatment decisions.

  • Profile Name Lung Cancer Panel 1 Complete Molecular
  • Sample Type Tissue
  • Preparations Required No special preparation is required for this test.
  • Report Time 3 Days

The panel uses Amplification Refractory Mutation System (ARMS) PCR for EGFR mutation detection, one of the most common genetic changes in lung adenocarcinoma, a subtype of NSCLC. For the identification of ALK, ROS1, RET gene rearrangements, and MET gene amplification, Fluorescence In Situ Hybridization (FISH) technique is used. These gene alterations are less common but are associated with specific subtypes of NSCLC and can be targeted by certain therapies.

Home Sample Collection Process
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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This test helps identify specific genetic changes that might be driving the cancer's growth. By knowing this, doctors can personalize treatment plans to target these specific changes, improving the efficacy of treatment and survival rates.

A tissue sample for this test is typically collected through a biopsy procedure, where a small piece of the tumor is removed for testing. This can be done through different methods, such as a needle biopsy, bronchoscopy, or surgery, depending on the location and size of the tumor.

Yes, this test doesn't require any dietary restrictions. However, if the biopsy procedure requires anesthesia, you may need to fast before the procedure. Your doctor will provide specific instructions based on your circumstances.

The risks associated with this test are primarily related to the biopsy procedure used to collect the tissue sample. These may include infection, bleeding, or complications from anesthesia. The test itself, however, does not pose any risks.

The turnaround time for the Lung Cancer Panel 1 Complete Molecular is usually 1-2 weeks. However, this can vary depending on the laboratory processing the sample.

If your test results show a mutation, your doctor will discuss the results with you and explain what they mean for your treatment options. Certain mutations may make you eligible for targeted therapies, which can be more effective and cause fewer side effects than traditional chemotherapy.

While this test can provide valuable information about the genetic makeup of your cancer, it is not typically used to monitor response to treatment. Other tests, such as imaging studies or blood tests, may be used for this purpose.

If no mutation is found, it means that none of the genetic changes tested in this panel are present in your tumor. However, this doesn't mean that no mutations exist. There are many other genetic changes not included in this panel that could still be driving your cancer.

This test is most useful for patients with non-small cell lung cancer, particularly adenocarcinoma. It may not provide useful information for other types of cancer or other lung diseases.

While the techniques used in this test are highly sensitive and specific, no test is 100% accurate. There is always a small chance of false positive or false negative results. Discuss any concerns you have with your doctor.

This test can provide some information about the likely course of your disease based on the presence of certain genetic changes, but many other factors also influence cancer progression.

Yes, the results of your test are confidential and are typically shared only with your healthcare team.

Coverage varies by insurance company and policy, so it's important to check with your insurance provider to determine if this test is covered.

Not all hospitals have the facilities to perform this complex test. It's usually done in specialized laboratories or larger hospitals with a dedicated pathology department.

In some cases, your doctor might recommend repeating this test if your cancer changes or progresses, or if you start a new treatment.

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