VDRL Reflex TPHA Confirmation Test Cost in Hyderabad

Patient Preparing : None. No special preparation, fasting, or water restrictions are needed for this test.

₹ 550


The Venereal Disease Research Laboratory (VDRL) Reflex Treponema pallidum Hemagglutination (TPHA) Confirmation test is a series of blood tests used to detect the presence of antibodies against the bacterium Treponema pallidum, the causative agent of syphilis. Syphilis is a sexually transmitted infection that can cause serious health problems if not treated promptly. Initially, the VDRL test is conducted, which is a non-specific test that can detect any condition causing damage to body tissues. If the VDRL test is positive, it indicates the potential presence of a syphilis infection. To confirm this, the TPHA test is done.

The TPHA test is a more specific test for syphilis and looks for antibodies that are only produced in response to a T. pallidum infection. Hence, a positive VDRL test followed by a positive TPHA test is a reliable indication of a current or past syphilis infection. These tests can help ensure prompt treatment to prevent complications from syphilis.

Test Name VDRL Reflex TPHA Confirmation
Sample Type Blood
Preparations Required None. No special preparation, fasting, or water restrictions are needed for this test.
Report Time 6 hours
Price in Hyderabad ₹ 550

What is the VDRL Test?

The VDRL test is a non-specific test that detects any condition causing damage to body tissues. It's often used as a first-line test for detecting syphilis.

What is the TPHA Test?

The TPHA test is a more specific test that looks for antibodies only produced in response to a Treponema pallidum infection.

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Why is a Reflex TPHA Confirmation needed?

The VDRL test can sometimes yield false-positive results. Therefore, a positive VDRL test is confirmed with a more specific TPHA test.

What do the results mean?

A positive VDRL and TPHA test result suggests a current or past syphilis infection. A negative result usually indicates no infection.

What if I have a negative VDRL but a positive TPHA?

It can happen in cases of past, treated syphilis infection where VDRL becomes negative, but TPHA remains positive.

Can I take the test while pregnant?

Yes, pregnant women are typically screened for syphilis to prevent transmission to the unborn child.

Do I need to fast before this test?

No, fasting is not required for this test.

Can these tests diagnose other sexually transmitted diseases (STDs)?

No, these tests specifically detect syphilis. Separate tests are needed for other STDs.

Can I have syphilis even if my partner tests negative?

Yes, as symptoms of syphilis may not appear immediately after infection. It's important to get tested if you have any risk factors.

What is the treatment for syphilis?

Syphilis is usually treated with antibiotics, and the earlier the treatment begins, the less damage the infection can cause.

How can I prevent syphilis?

Safe sex practices, including using condoms and regular STD testing, can help prevent syphilis.

Can I get tested for syphilis at home?

No, a blood sample must be taken by a healthcare provider for this test.

Can I get syphilis more than once?

Yes, having syphilis once does not protect you from getting it again.

What should I do if I have a positive result?

If you have a positive result, follow up with your healthcare provider promptly to discuss treatment options.

How often should this test be done?

The frequency of this test depends on your individual risk factors and your healthcare provider's recommendations.

Can pregnant women take this test?

Yes, in fact, this test is typically included in the routine screening tests performed early in pregnancy due to the risk of transmitting syphilis to the baby.

How can I prevent syphilis?

Practicing safe sex, using condoms, and having regular check-ups can help prevent syphilis. If you test positive, it's important to notify your sexual partners so they can also get tested and treated if necessary.

Is syphilis curable?

Yes, syphilis is curable with appropriate antibiotic treatment, but it's important to catch it early to prevent long-term complications.

What happens if syphilis is left untreated?

If left untreated, syphilis can progress to its later stages, which can cause serious damage to the heart, brain, and other organs, and can potentially be life-threatening.

How is syphilis transmitted?

Syphilis is transmitted through direct contact with a syphilis sore during vaginal, anal, or oral sex. It can also be passed from an infected mother to her baby during pregnancy.

Can syphilis be prevented with a vaccine?

Currently, there is no vaccine available to prevent syphilis. The most effective methods of prevention are practicing safe sex and having regular check-ups.

What are the symptoms of syphilis?

The symptoms of syphilis vary depending on the stage of the disease. In its early stage, it may present as a painless sore or rash. Later, it can cause symptoms such as fever, fatigue, weight loss, and aches and pains. If left untreated, it can lead to serious complications affecting the heart, brain, and other organs.

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