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Lithium

Tumor Necrosis Factor Alpha (TNF Alpha - IHC)

Tumor Necrosis Factor Alpha (TNF Alpha) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. The Immunohistochemistry (IHC) test for TNF Alpha detects the presence and localization of this protein in tissue samples.

This test plays a crucial role in the assessment of inflammatory and autoimmune diseases, as well as certain cancers. Elevated levels of TNF Alpha have been associated with diseases like rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease (IBD), psoriasis, and cancer.


  • Test NameTumor Necrosis Factor Alpha (TNF Alpha - IHC)
  • Sample TypeTissue
  • Preparations RequiredAs the sample type is tissue, it is usually obtained through a biopsy performed by a healthcare professional. Please follow any specific pre-procedure instructions by doctor.
  • Report Time7 days

Why is a TNF Alpha (IHC) test performed?

The TNF Alpha (IHC) test is performed to help diagnose and monitor the treatment of certain inflammatory diseases and cancers. This test can provide insight into the inflammatory process occurring in your body.

How is the TNF Alpha (IHC) test performed?

This test requires a tissue sample, typically obtained through a biopsy procedure. The sample is then processed and examined under a microscope using immunohistochemical techniques to detect the presence of TNF Alpha.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

Any discomfort or pain would be related to the biopsy procedure used to obtain the tissue sample. The level of discomfort varies depending on the biopsy site and the individual's pain tolerance.

The presence and amount of TNF Alpha in the tissue sample can indicate ongoing inflammation or disease. Your healthcare provider will interpret your results in the context of your symptoms, medical history, and other test results.

This test can be performed during pregnancy if necessary, but it's essential to inform your healthcare provider about your pregnancy status.

The frequency of this test depends on your individual health condition and your healthcare provider's advice.

Certain medications may affect the levels of TNF Alpha. Be sure to inform your healthcare provider about all the medications and supplements you're taking.

Abnormal results should be discussed with your healthcare provider. They may suggest further testing or changes to your treatment plan.

This test may be ordered along with other tests that assess inflammation, autoimmune conditions, or cancer. Your healthcare provider will decide on the appropriate tests based on your symptoms and medical history.

Maintaining a healthy lifestyle can support your overall well-being and help manage inflammation. However, significant changes in TNF Alpha levels typically require medical intervention.

A positive result indicates the presence of TNF Alpha in the tissue sample, suggesting inflammation or disease. Further evaluation is usually required to confirm a diagnosis.

As this test requires a tissue sample, the timing will depend on when the biopsy procedure is scheduled. Your healthcare provider will provide more specific instructions.

Yes, this test can be used for individuals of all ages if a certain inflammatory condition or cancer is suspected.

Post-procedure activities will depend on the biopsy type and site. Your healthcare provider will give you specific instructions regarding recovery.

Yes, it's possible. While elevated TNF Alpha levels can indicate certain diseases, normal levels don't necessarily mean you're disease-free. Other tests and your symptoms and medical history will guide the diagnosis and treatment process.

The TNF Alpha (IHC) test is generally reliable for detecting the presence of TNF Alpha in tissue samples. However, the results should always be interpreted in the context of your overall health, symptoms, and other test results.

Typically, you can expect your TNF Alpha (IHC) test results within 7-10 days, although this can vary depending on the laboratory.

If you have an inflammatory condition or cancer, your healthcare provider may recommend periodic testing to monitor your condition. The frequency of these tests will depend on your individual circumstances.

Certain factors, such as medications, other health conditions, and the quality of the tissue sample, can affect the results of this test. Be sure to share your complete medical history with your healthcare provider to ensure accurate interpretation of your test results.

Your healthcare provider will give you specific instructions based on the type of biopsy you're having. These may include fasting or temporarily stopping certain medications.

The risks associated with this test are related to the biopsy procedure, which can include pain, infection, and bleeding at the biopsy site. There is minimal risk associated with the immunohistochemistry process itself.

The TNF Alpha (IHC) test can help diagnose many, but not all, inflammatory conditions or cancers. Other tests may be necessary for a comprehensive evaluation of your health.

A positive result may require further investigation. Your healthcare provider will guide you through the next steps, which may include additional tests or treatment.

Yes, conditions other than inflammatory disorders or cancers can also affect TNF Alpha levels. These include infections, chronic diseases, and some medications.

Recovery time varies based on the type of biopsy and the individual. Your healthcare provider will give you an estimated recovery time and instructions for post-procedure care.

Yes, changes in TNF Alpha levels can indicate whether a treatment is working. Your healthcare provider will interpret these changes in the context of your overall treatment plan.

Elevated TNF Alpha levels are associated with inflammation, which can cause various symptoms depending on the affected body part. Your healthcare provider can help you understand the relationship between your test results and symptoms.

A healthy diet and regular exercise can contribute to overall well-being and help manage inflammation. However, medical intervention is often necessary for conditions associated with high TNF Alpha levels.

Yes, this test requires a biopsy, which is a medical procedure performed by a healthcare professional. A doctor's referral is necessary.

High TNF Alpha levels are linked to chronic inflammation, which can lead to various complications, including tissue damage, autoimmune diseases.

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