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Lithium

TSH Receptor Antibodies

The Thyroid Stimulating Hormone (TSH) Receptor Antibodies (TRAb) test, also known as the Thyrotropin Receptor Antibodies test, is a diagnostic test used to detect specific antibodies that are often present in certain thyroid conditions. These antibodies target receptors for TSH on the thyroid gland and can cause disruptions in the production of thyroid hormones, resulting in conditions like Graves' disease and Hashimoto's thyroiditis.

The test is typically performed when symptoms of a thyroid disorder are present but other thyroid tests are inconclusive, or when a definitive diagnosis is needed to guide treatment. The TRAb test is an important tool for diagnosing autoimmune thyroid diseases and monitoring the effectiveness of treatments for these conditions.


  • Test NameTSH Receptor Antibodies
  • Sample TypeBlood
  • Preparations RequiredNo specific instructions required. No fasting is necessary, and there are no restrictions on food, beverage, or medication consumption prior to the test.
  • Report Time6 hours

What is the TSH Receptor Antibodies test?

The TSH Receptor Antibodies (TRAb) test is a blood test that measures the level of TRAb in the blood. These antibodies can interfere with the function of the thyroid gland and lead to thyroid diseases.

Why would I need a TRAb test?

Your healthcare provider might order a TRAb test if you have symptoms of an autoimmune thyroid disorder, such as Graves' disease or Hashimoto's thyroiditis, especially if other thyroid tests are inconclusive.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

Elevated levels of TRAb can indicate the presence of an autoimmune thyroid disorder. However, the interpretation of the results should always be in the context of your symptoms and other test results.

The test requires a small blood sample, usually taken from a vein in your arm.

The risks associated with the TRAb test are minimal and similar to those of any routine blood test, including minor bruising or infection at the puncture site.

TSH receptors are found on the surface of thyroid cells. They bind to TSH, which signals the thyroid gland to produce and release thyroid hormones, which are essential for regulating the body's metabolism.

High levels of TRAb can interfere with the normal functioning of the thyroid gland, leading to conditions such as Graves' disease, where the thyroid is overactive, or Hashimoto's thyroiditis, where the thyroid is underactive.

Stimulating TRAb mimic TSH and stimulate the thyroid gland to produce excess thyroid hormone, leading to hyperthyroidism. Blocking TRAb prevent TSH from activating the thyroid gland, resulting in hypothyroidism.

No specific preparation is required for the TRAb test. You don't need to fast or stop any medication unless instructed by your healthcare provider.

The turnaround time for TRAb test results is typically 1-3 days, but this can vary depending on the laboratory.

Yes, it's possible. The TRAb test is only one piece of the puzzle, and it's possible to have a thyroid disorder with normal TRAb levels. Other tests, along with your symptoms and medical history, are also important in diagnosing thyroid diseases.

Yes, there are. While the TRAb test is very specific, it's not very sensitive. This means that while a positive result is highly indicative of an autoimmune thyroid disease, a negative result doesn't completely rule it out.

Yes, pregnancy can affect TRAb levels, and it's important to monitor them in pregnant women with a history of Graves' disease. High levels can increase the risk of neonatal thyroid disease.

Yes, TRAb levels can fluctuate, particularly with the onset or remission of autoimmune thyroid diseases. Monitoring TRAb levels can be useful in tracking the course of the disease and the effectiveness of treatment.

The treatment for high TRAb levels typically involves treating the underlying autoimmune thyroid disease. This may include medication, radiation therapy, or surgery.

The TRAb test is more specific but less sensitive than other thyroid tests. It's typically used in conjunction with tests like TSH, free T4, and thyroid peroxidase antibodies to provide a more complete picture of thyroid function and health.

There's some evidence to suggest that stress can trigger an autoimmune response and potentially affect TRAb levels. However, more research is needed in this area.

There's no definitive evidence to suggest that TRAb levels can be lowered naturally. However, maintaining a healthy lifestyle, managing stress, and avoiding known triggers for autoimmune disease may potentially help manage TRAb levels and thyroid health.

Yes, it's possible to have a thyroid disorder without noticeable symptoms, particularly in the early stages of the disease. This is why regular check-ups and screening tests are important, especially if you have risk factors for thyroid disease.

The frequency of TRAb testing depends on various factors, including your symptoms, current health status, and whether you're undergoing treatment for a thyroid disorder. Your healthcare provider can provide specific guidance.

The TRAb test is a valuable tool for diagnosing autoimmune thyroid diseases, particularly when used alongside other diagnostic tests. By detecting the presence of TSH receptor antibodies, the test can help determine whether your body is attacking its own thyroid gland, leading to disorders like Graves' disease or Hashimoto's thyroiditis. Understanding the results and their implications can provide crucial insights into your thyroid health and guide the way toward effective treatment and management strategies.

TSH RECEPTOR ANTIBODIES
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  • 5KM from Shaikpet