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Sperm DNA Fragmentation Assay

The Sperm DNA Fragmentation Assay is a specialized diagnostic test used to evaluate the integrity of DNA within sperm cells. It plays a significant role in assessing male fertility, and can help to identify potential issues that might contribute to infertility or repeated pregnancy loss.


  • Test NameSperm DNA Fragmentation Assay
  • Sample TypeSemen
  • Preparations RequiredBefore the test, you should abstain from sexual activity for about 2 to 5 days to ensure the best sample.
  • Report Time6 days

What is the Sperm DNA Fragmentation Assay?

The Sperm DNA Fragmentation Assay is a laboratory test that measures the percentage of sperm cells in a semen sample with fragmented DNA. High levels of DNA fragmentation may contribute to male infertility.

Why is the Sperm DNA Fragmentation Assay done?

This test is done when a couple is having difficulty conceiving, or if there have been recurrent miscarriages. It helps in determining if the male partner has a high percentage of sperm with fragmented DNA, which can impair fertility.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No, fasting is not required for this test.

The test measures the percentage of sperm cells in a sample that have damaged or fragmented DNA.

This test is typically done as part of an infertility workup, or when a couple experiences repeated pregnancy losses. Consult with your doctor for the best guidance.

Typically, a value of less than 15% DNA fragmentation is considered normal. However, the reference range can vary between labs, so it's important to discuss your specific results with your doctor.

You should abstain from ejaculation for 2-5 days before the test to ensure a good quality sample. After the test, no specific precautions are necessary.

Lifestyle choices such as smoking, excessive alcohol consumption, drug use, poor diet, and exposure to environmental toxins can potentially affect sperm DNA integrity and the results of this test.

Age is a non-modifiable factor that can impact sperm DNA integrity. As men age, there may be a greater chance of DNA fragmentation in sperm.

You should consult a fertility specialist or a urologist for an in-depth interpretation of the results.

Yes, certain medical conditions, such as varicocele, infections, or diseases can affect sperm DNA integrity.

High levels of sperm DNA fragmentation may indicate a greater likelihood of infertility, or a higher risk of pregnancy loss if conception does occur.

Certain medications, particularly those affecting reproductive health, could potentially influence the results of this test.

Improving overall lifestyle, including quitting smoking, reducing alcohol intake, maintaining a healthy diet, and regular exercise can potentially improve sperm DNA integrity.

Men with certain medical conditions, older age, or unhealthy lifestyle habits may have a higher likelihood of abnormal results.

No, this test requires specific laboratory equipment and should be performed in a medical laboratory.

A sudden change in sperm DNA fragmentation can reflect alterations in overall sperm health and quality, which could potentially impact fertility.

A balanced diet, regular exercise, avoidance of harmful substances like tobacco and excessive alcohol, and regular check-ups can help maintain healthy sperm DNA.

There are minimal physical risks associated with this test. However, receiving abnormal results can potentially cause emotional or psychological distress.

While the test is considered reliable in assessing sperm DNA integrity, it's one of many factors to consider in a comprehensive fertility evaluation.

The Sperm DNA Fragmentation Assay is a valuable diagnostic tool in understanding male fertility. It provides crucial insights into sperm quality, going beyond conventional semen analysis. As always, it's important to discuss with your doctor any concerns or questions regarding this test.

SPERM DNA FRAGMENTATION
₹ 6600
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet