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Soluble Transferrin Receptor (sTFR)

The Soluble Transferrin Receptor (sTFR) test is a blood test used to assess iron status in the body. This test is particularly useful in differentiating between iron deficiency anemia and anemia of chronic disease.


  • Test NameSoluble Transferrin Receptor (sTFR)
  • Sample TypeSerum
  • Preparations RequiredThere are no specific preparations required for this test.
  • Report Time4 Days

What is the Soluble Transferrin Receptor (sTFR) test?

The sTFR test is a blood test that measures the amount of soluble transferrin receptors, a marker of iron status, in your blood.

Why is the Soluble Transferrin Receptor (sTFR) test done?

This test is done to evaluate iron status and to help differentiate between iron deficiency anemia and anemia of chronic disease. It can also be useful in the diagnosis and monitoring of iron overload conditions.

Home Sample Collection Process

1
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2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

No, fasting is not generally required for this test.

The test measures the level of soluble transferrin receptors, a protein that reflects the total mass of cellular receptors in the body, in your blood.

The frequency of the test depends on your doctor's advice, usually based on your specific health condition or symptoms.

Normal values may vary based on the lab and the specific method used for testing. Generally, levels between 2.2 to 5 mg/L are considered normal.

There are no specific precautions needed for this test. However, it's always a good idea to inform your doctor about all medications and supplements you are taking.

Diet, medication use, and overall health can influence iron levels and thus sTFR levels.

Age, sex, and certain genetic factors can influence sTFR levels.

You should consult your primary care doctor or a hematologist if your results are abnormal.

Yes, conditions such as iron deficiency anemia, anemia of chronic disease, hemolytic anemia, and conditions causing iron overload can affect sTFR levels.

High levels of sTFR can indicate iron deficiency anemia, or increased red blood cell production as in hemolytic anemia or thalassemia.

Low levels of sTFR can be seen in conditions of iron overload, like hemochromatosis, or in certain chronic diseases.

Yes, certain medications, including those affecting iron absorption or red blood cell production, can affect sTFR levels.

Maintaining a balanced diet with adequate iron intake, managing underlying conditions, and adhering to prescribed medication can help improve your sTFR levels.

Yes, individuals with conditions affecting iron status, such as iron deficiency anemia, hemolytic anemia, thalassemia, or iron overload conditions, are more likely to have abnormal sTFR levels.

No, the Soluble Transferrin Receptor (sTFR) test involves a blood draw, which should be performed by a trained healthcare professional.

A sudden change in sTFR levels could indicate a change in iron status, possibly due to changes in diet, medication, or an underlying condition.

Maintaining a balanced diet with adequate iron intake, managing underlying conditions, and adhering to prescribed medication can help maintain normal sTFR levels.

The test involves a blood draw, which may cause minor discomfort, bruising, or in rare cases, infection.

Understanding your Soluble Transferrin Receptor (sTFR) test results can provide important insights into your body's iron status. However, the test is just one piece of the puzzle. It should be used in conjunction with other tests and evaluations for a comprehensive view of your health. Always consult with your healthcare provider if you have any concerns or questions about this test.

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