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Serum Ascitic Albumin Gradient (SAAG)

The Serum Ascitic Albumin Gradient (SAAG) test is an important diagnostic tool used to determine the cause of ascites, which is an abnormal buildup of fluid in the abdomen. The SAAG is calculated by subtracting the ascitic fluid albumin level from the serum albumin level. It helps distinguish between ascites caused by portal hypertension, such as in cirrhosis or heart failure, and ascites due to other causes, such as cancer or tuberculosis.


  • Test NameSerum Ascitic Albumin Gradient (SAAG)
  • Sample TypeSerum and Ascitic Fluid
  • Preparations RequiredNo special preparation is required for this test.
  • Report Time₹ 4 Hours

The SAAG has revolutionized the approach to ascites and has greatly simplified the differential diagnosis. The calculation is preferred over traditional methods since it is more accurate and less influenced by diuretic use or paracentesis, a procedure used to remove ascitic fluid.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

This test is done to help determine the cause of ascites, an abnormal buildup of fluid in the abdomen.

No, fasting is not required for this test.

The test measures the gradient (difference) between the albumin level in your blood and the albumin level in your ascitic fluid.

The frequency of this test depends on your doctor's recommendation, based on your health status and any symptoms you may have.

A SAAG of 1.1 g/dL or higher usually indicates ascites due to portal hypertension, while a SAAG less than 1.1 g/dL suggests other causes. However, these values can vary slightly between labs.

There are no specific precautions needed before or after the test. However, be sure to inform your doctor about all the medications and supplements you are taking.

The use of diuretics and certain other medications can affect the albumin levels in the serum and ascitic fluid.

Non-modifiable factors include certain liver diseases, heart failure, cancer, and certain infections that can influence the SAAG.

You should consult your doctor if your test results are abnormal. They can help you understand what the results mean for your health.

The risks associated with this test are minimal and mainly relate to the drawing of blood and ascitic fluid. Potential risks include slight pain, bruising, or infection at the puncture site.

Yes, conditions like liver disease, heart failure, cancer, and certain infections can affect the SAAG.

Yes, certain medications such as diuretics can affect albumin levels and thus the SAAG. Always inform your doctor about any medications you are taking.

A high SAAG indicates ascites due to portal hypertension, which is often related to liver disease or heart failure. A low SAAG suggests other causes of ascites, such as cancer or infection.

Test results are a measure of your health condition and not something you can improve per se. However, managing underlying conditions, such as liver disease or heart failure, may help to resolve ascites.

Treatments will depend on the cause of the abnormal SAAG. This might involve medication, dietary changes, or in severe cases, procedures to drain the excess fluid.

People with conditions like liver disease, heart failure, cancer, and certain infections are more likely to have an abnormal SAAG.

No specific preparation is needed for this test, but make sure to inform your doctor about your complete medical history and any medications you are currently taking.

Consistently high or low SAAG could suggest an ongoing medical condition that requires further investigation and treatment.

The SAAG is highly accurate in distinguishing between causes of ascites and is less influenced by factors that can affect traditional methods.

Your doctor may order other tests such as liver function tests, imaging studies, or tests for heart function based on your symptoms and medical history.

The SAAG is a critical component of the diagnostic approach to ascites. If you're undergoing this test, understand that it's part of a broader investigation into your health. Always discuss your results with your doctor, who can interpret them in the context of your overall health and guide you toward effective treatment strategies.

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