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Rh Antibody Titre (Anti D/Coomb's titre- Automated)

The Rh (Rhesus) Antibody Titre is a blood test that is primarily used during pregnancy to determine the mother's Rh blood type (Rh positive or Rh negative), and to check whether she has developed antibodies against the Rh antigen. The Rh antigen is a protein found on the red blood cells (RBCs) of about 85% of people, and they are termed Rh positive. Those who lack the Rh antigen are referred to as Rh negative. This is particularly important in cases where an Rh-negative woman is pregnant with an Rh-positive fetus. The immune system of the Rh-negative mother may recognize the Rh antigen on the fetal blood cells as foreign and produce antibodies against it, a process known as Rh sensitization. The Rh Antibody Titre test measures the levels of these antibodies in the mother's blood.


  • Test NameRh Antibody Titre (Anti D/Coomb's titre- Automated)
  • Sample TypeBlood
  • Preparations Required24 hours
  • Report TimeNo special preparation is required for this test.

A person can also become sensitized following an Rh-incompatible blood transfusion or organ transplant. The development of antibodies can lead to complications, such as hemolytic disease in a newborn or hemolytic transfusion reactions. Hence, this test is useful to avoid such conditions by monitoring the antibody levels.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is performed to determine if a person has developed antibodies against the Rh antigen, especially in an Rh-negative pregnant woman carrying an Rh-positive baby. It's also done after an Rh- incompatible blood transfusion or organ transplant.

Rh sensitization occurs when an Rh-negative individual is exposed to Rh-positive blood, stimulating their immune system to produce antibodies against the Rh antigen. This can cause complications in subsequent pregnancies or after Rh-incompatible blood transfusions.

Rh sensitization does not typically cause symptoms in the mother. However, if her antibodies cross the placenta and attack the baby's red blood cells, it can lead to hemolytic disease of the newborn, which can cause symptoms such as jaundice, anemia, heart failure, or even death in severe cases.

Along with the ABO blood type, the Rh factor is crucial in determining blood compatibility for transfusions. Giving Rh-positive blood to an Rh-negative person can stimulate the production of Rh antibodies, leading to a transfusion reaction.

Rh incompatibility is typically managed with the administration of a medicine called Rh immunoglobulin (RhIg) around the 28th week of pregnancy and within 72 hours after delivery, miscarriage, or abortion to prevent the mother from developing Rh antibodies.

Yes, Rh-negative individuals can donate blood to both Rh-positive and Rh-negative individuals. However, Rh-positive individuals cannot donate to Rh-negative individuals due to the risk of Rh sensitization.

A positive result indicates that Rh antibodies are present in the blood, which can occur due to Rh sensitization during pregnancy, following an Rh-incompatible blood transfusion or organ transplant.

The frequency of this test during pregnancy may vary based on your healthcare provider's advice. It is usually performed around the 28th week of pregnancy and within 72 hours after delivery in Rh-negative mothers.

Rh-negative individuals should always inform their healthcare provider about their blood type before any blood transfusion or organ transplant. Pregnant women should also inform their obstetrician about their Rh status during prenatal visits.

The test involves a simple blood draw and carries minimal risks, such as slight pain or bruising at the injection site. There's also a minimal risk of infection.

No, this test requires a blood sample, which should be collected by a healthcare professional in a clinical setting.

Rh incompatibility is usually diagnosed with a blood test that determines the mother's blood type and Rh factor and screens for Rh antibodies. If the mother is Rh-negative and the father is Rh-positive, the baby could be at risk for Rh incompatibility.

The test is performed on a blood sample, which is drawn from a vein in your arm using a needle.

Yes, you can eat and drink normally before the test. There are no special dietary restrictions unless directed otherwise by your doctor.

Your healthcare provider will discuss the results with you. If you have any questions about the test or the results, do not hesitate to ask.

The test is highly accurate when performed in a reputable laboratory. However, like all tests, there may be a small chance of false positive or false negative results.

Certain medications can affect the test results, including some antibiotics and blood pressure medications. Make sure to inform your healthcare provider about any medications you are currently taking.

It is generally safe to perform this test even if you have a cold or fever. However, if you are severely ill, your doctor may advise you to postpone the test.

If the test results show that you have developed Rh antibodies, your healthcare provider will discuss the next steps with you, which may include further testing and treatment.

The Rh factor is less significant during organ transplantation than during blood transfusions. The main focus during organ transplantation is the matching of tissue types rather than blood types.

Rh Antibody Titre (Anti D/Coomb's titre- Automated)
₹ 850
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