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Pyruvate (Pyruvic acid) – Blood

Pyruvate, or pyruvic acid, is a key substance in the body's energy production processes. It plays a significant role in both aerobic and anaerobic metabolism. When cells break down sugar (glucose), they produce pyruvate. Depending on the availability of oxygen, pyruvate can either be further broken down to release more energy, or it can be converted to lactate. The balance between lactate and pyruvate is crucial to maintain the body's pH level. A blood test for pyruvate can be useful in diagnosing several inherited metabolic disorders and other conditions affecting energy metabolism.


  • Test NamePyruvate (Pyruvic acid) – Blood
  • Sample TypeBlood
  • Preparations RequiredNo specific dietary restrictions are required, but stay hydrated and maintain your regular diet unless otherwise instructed by your healthcare provider.
  • Report Time24 hours

What is a pyruvate test?

A pyruvate test measures the level of pyruvate, or pyruvic acid, in the blood. This can provide useful information about the body's energy metabolism.

Why might I need a pyruvate test?

Your healthcare provider might order a pyruvate test if they suspect you have a metabolic disorder or a condition affecting energy metabolism. This could include inherited metabolic disorders or conditions like lactic acidosis.

Home Sample Collection Process

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Reporting of the sample at lab
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Frequently Asked Questions

A pyruvate test is performed using a blood sample, which is drawn from a vein in your arm by a healthcare professional.

A high level of pyruvate can indicate a problem with the body's energy metabolism processes. It may be a sign of a metabolic disorder or a condition like lactic acidosis.

The level of pyruvate in your blood can be affected by a number of factors, including your diet, exercise, and the presence of any metabolic disorders. Make sure to tell your healthcare provider about any medications or supplements you're taking, as these can also influence your results.

If your pyruvate levels are abnormal, your healthcare provider will likely order further tests to determine the cause and develop a treatment plan.

The frequency of testing will depend on your specific health condition and your healthcare provider's recommendations.

A pyruvate test is not designed to detect cancer, but abnormal pyruvate levels can sometimes be seen in people with cancer due to changes in metabolism.

Pyruvate and lactate are related through a process known as the Cori cycle. When there's insufficient oxygen for pyruvate to enter the Krebs cycle, it gets converted to lactate.

Pyruvate levels are influenced by the body's metabolic processes, which can be affected by factors such as diet, exercise, and overall health. However, it's important to follow your healthcare provider's advice regarding any changes that may affect these levels.

The risks associated with the pyruvate test are minimal and are similar to those of any other blood test. They include minor pain or bruising at the puncture site, fainting or feeling lightheaded, and infection.

If you have a metabolic disorder that affects pyruvate levels, your healthcare provider will develop a treatment plan that may involve dietary changes, medication, or other interventions.

Pyruvate plays a crucial role in the body's energy production processes. It's produced when cells break down sugar, and depending on the availability of oxygen, it can either be broken down further to release energy or converted to lactate.

A pyruvate test might be performed alongside other tests, such as a lactate test or tests for various metabolic disorders.

If you have any concerns about your pyruvate test results, it's important to discuss them with your healthcare provider. They can help you understand what the results mean and what steps you should take next.

In summary, a pyruvate test is a crucial part of understanding metabolic processes and diagnosing related disorders. The test is simple and minimally invasive, providing valuable information to healthcare providers. As with any medical concern, communication with your healthcare provider is key in understanding test results and the best course of action moving forward.

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