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Test

PSA (Total) with Free-PSA and Ratio (Free:Total)

The PSA (Prostate-Specific Antigen) with Free-PSA and Ratio test measures the levels of total PSA and free PSA in the blood and calculates their ratio. PSA is a protein produced by both normal and cancerous prostate cells. Most PSA in the blood is bound to other proteins, but some remains free. Calculating the ratio of free to total PSA can help determine the likelihood of prostate cancer, especially in men with total PSA values in the borderline range.

  • Test NamePSA (Total) with Free-PSA and Ratio (Free:Total)
  • Sample TypeBlood
  • Preparations RequiredNo specific fasting or preparations are needed for this test. However, avoid vigorous physical activity or procedures involving the prostate such as a biopsy, cystoscopy, or catheter placement prior to the test, as these can artificially increase PSA levels.
  • Report Time4 hours
What is the purpose of the total PSA, free-PSA, and ratio test?

This test helps detect prostate cancer at an early stage and assists doctors in differentiating between cancerous and non-cancerous conditions of the prostate.

What do my test results mean?

A higher total PSA level along with a lower free to total PSA ratio may indicate a higher risk of prostate cancer. However, these results alone are not diagnostic and further tests may be required.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test involves a routine blood draw which may cause slight discomfort or bruising at the puncture site.

Yes, a high total PSA level can be due to benign prostatic hyperplasia (BPH), prostatitis (inflammation of the prostate), or even recent physical activities.

Total PSA measures all forms of PSA in the blood (both bound and unbound) whereas the free PSA test measures only the unbound form.

Factors such as age, race, certain medications, recent prostate manipulations (e.g., biopsy, surgery), and infections can affect your PSA levels.

If your PSA levels are high, your doctor may recommend a prostate biopsy to check for the presence of cancer.

The frequency of testing depends on your personal risk factors for prostate cancer. Discuss this with your doctor to determine an appropriate screening schedule.

Typically, a lower free:total PSA ratio (less than 0.10) might suggest a higher risk of prostate cancer. However, individual lab reference ranges may vary.

Certain medications and supplements can lower PSA levels. However, it's important to discuss any changes in medication or supplement regimen with your doctor as this could mask the true PSA level and potentially delay the diagnosis of prostate cancer.

Yes, the PSA test is often used to monitor response to treatment in men with prostate cancer.

Yes, there are no dietary restrictions before the test. However, it is best to avoid vigorous exercise or any procedure involving the prostate before the test.

If your PSA levels are high, your doctor may suggest a digital rectal exam (DRE), a prostate biopsy, or imaging studies like an ultrasound or MRI.

Although you can't prevent prostate cancer entirely, maintaining a healthy lifestyle, which includes a balanced diet, regular exercise, and regular medical checkups can help reduce your risk.

While the PSA test is a valuable tool, it is not definitive. False positives and false negatives can occur. Therefore, it's just one tool your doctor will use in determining your risk for prostate cancer.

Understanding your PSA levels can provide crucial insights into your prostate health. However, it's just one piece of the puzzle. Regular screening and maintaining an open dialogue with your healthcare provider can help ensure that potential health issues are addressed in a timely manner. Always remember, early detection greatly improves the chances of successful treatment and management of prostate cancer.

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