PSA (Prostate-Specific Antigen) with Free-PSA and Ratio Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific fasting or preparations are needed for this test. However, avoid vigorous physical activity or procedures involving the prostate such as a biopsy, cystoscopy, or catheter placement prior to the test, as these can artificially increase PSA levels.

₹ 1700


The PSA (Prostate-Specific Antigen) with Free-PSA and Ratio test measures the levels of total PSA and free PSA in the blood and calculates their ratio. PSA is a protein produced by both normal and cancerous prostate cells. Most PSA in the blood is bound to other proteins, but some remains free. Calculating the ratio of free to total PSA can help determine the likelihood of prostate cancer, especially in men with total PSA values in the borderline range.

Test Name PSA (Total) with Free-PSA and Ratio (Free:Total)
Sample Type Blood
Preparations Required No specific fasting or preparations are needed for this test. However, avoid vigorous physical activity or procedures involving the prostate such as a biopsy, cystoscopy, or catheter placement prior to the test, as these can artificially increase PSA levels.
Report Time 4 hours
Price in Hyderabad ₹ 1700

What is the purpose of the total PSA, free-PSA, and ratio test?

This test helps detect prostate cancer at an early stage and assists doctors in differentiating between cancerous and non-cancerous conditions of the prostate.

What do my test results mean?

A higher total PSA level along with a lower free to total PSA ratio may indicate a higher risk of prostate cancer. However, these results alone are not diagnostic and further tests may be required.

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Does this test hurt?

This test involves a routine blood draw which may cause slight discomfort or bruising at the puncture site.

Can a high total PSA level indicate conditions other than prostate cancer?

Yes, a high total PSA level can be due to benign prostatic hyperplasia (BPH), prostatitis (inflammation of the prostate), or even recent physical activities.

How does the free PSA test differ from the total PSA test?

Total PSA measures all forms of PSA in the blood (both bound and unbound) whereas the free PSA test measures only the unbound form.

What factors can affect the results of my test?

Factors such as age, race, certain medications, recent prostate manipulations (e.g., biopsy, surgery), and infections can affect your PSA levels.

What happens if my PSA levels are high?

If your PSA levels are high, your doctor may recommend a prostate biopsy to check for the presence of cancer.

How often should I get tested?

The frequency of testing depends on your personal risk factors for prostate cancer. Discuss this with your doctor to determine an appropriate screening schedule.

What is the normal ratio of free:total PSA?

Typically, a lower free:total PSA ratio (less than 0.10) might suggest a higher risk of prostate cancer. However, individual lab reference ranges may vary.

Can I take supplements or medications to lower my PSA levels?

Certain medications and supplements can lower PSA levels. However, it's important to discuss any changes in medication or supplement regimen with your doctor as this could mask the true PSA level and potentially delay the diagnosis of prostate cancer.

Can the PSA test be used to monitor my response to treatment for prostate cancer?

Yes, the PSA test is often used to monitor response to treatment in men with prostate cancer.

Can I eat or drink before my PSA test?

Yes, there are no dietary restrictions before the test. However, it is best to avoid vigorous exercise or any procedure involving the prostate before the test.

What other tests might my doctor recommend if my PSA levels are high?

If your PSA levels are high, your doctor may suggest a digital rectal exam (DRE), a prostate biopsy, or imaging studies like an ultrasound or MRI.

Is there anything I can do to prevent prostate cancer?

Although you can't prevent prostate cancer entirely, maintaining a healthy lifestyle, which includes a balanced diet, regular exercise, and regular medical checkups can help reduce your risk.

How reliable is the PSA test in detecting prostate cancer?

While the PSA test is a valuable tool, it is not definitive. False positives and false negatives can occur. Therefore, it's just one tool your doctor will use in determining your risk for prostate cancer.

Understanding your PSA levels can provide crucial insights into your prostate health. However, it's just one piece of the puzzle. Regular screening and maintaining an open dialogue with your healthcare provider can help ensure that potential health issues are addressed in a timely manner. Always remember, early detection greatly improves the chances of successful treatment and management of prostate cancer.

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