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Lab Test

Primary Immunodeficiency Work-Up-Basic

What is the purpose of lymphocyte subsetting?

Lymphocyte subsetting helps evaluate the proportions and numbers of different lymphocyte populations, such as B cells, T cells, and natural killer (NK) cells. It provides important information about the functioning of the immune system and can aid in diagnosing certain immunodeficiency disorders.

How is the lymphocyte subsetting test performed?

The lymphocyte subsetting test is performed on a blood sample. Specialized laboratory techniques, such as flow cytometry, are used to identify and quantify the different lymphocyte populations present in the sample.

Home Sample Collection Process

1
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Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

Immunoglobulins, also known as antibodies, play a crucial role in the immune response. Measuring immunoglobulin levels, including IgG, IgA, and IgM, helps assess the overall immune function and detect deficiencies that may contribute to primary immunodeficiency disorders.

Abnormal lymphocyte subsetting results can suggest dysregulation or deficiencies in specific lymphocyte populations. It may indicate underlying primary immunodeficiency disorders or other immune system abnormalities.

Abnormal immunoglobulin levels can indicate deficiencies or dysregulation in the immune system. Low levels may suggest an increased susceptibility to infections, while high levels may indicate an overactive immune response or other underlying conditions.

Reference ranges for lymphocyte subsetting and immunoglobulin levels are established based on a healthy population. These ranges may vary slightly between different laboratories. Interpretation of results takes into account the individual's age, sex, and medical history.

The diagnostic tests included in the Primary Immunodeficiency Work-Up-Basic, such as lymphocyte subsetting and immunoglobulin measurement, are generally safe and well-tolerated. They involve a simple blood sample collection and do not pose significant risks or side effects.

Certain medications, such as immunosuppressants, and underlying medical conditions can potentially influence the test results. It is important to inform your healthcare provider about any medications or medical conditions you have before undergoing these tests to ensure accurate interpretation of the results.

While the Primary Immunodeficiency Work-Up-Basic provides valuable information, the diagnosis of primary immunodeficiency disorders often requires a comprehensive evaluation, including medical history, physical examination, and additional specialized tests. These tests serve as important pieces of the diagnostic puzzle but may not provide a definitive diagnosis on their own.

The frequency of these tests depends on various factors, including your medical history, symptoms, and initial results. Your healthcare provider will determine the appropriate timing for repeat testing, if necessary, based on your individual case.

There are typically no age restrictions for the Primary Immunodeficiency Work-Up-Basic tests. However, specific considerations may be required for infants or individuals with certain medical conditions. Your healthcare provider will guide you accordingly.

The coverage for these tests may vary depending on your insurance provider and specific policy. It is recommended to check with your insurance company beforehand to determine the extent of coverage and any associated costs.

If your test results are abnormal, it is important to follow up with your healthcare provider for further evaluation and guidance. They will assess your results in conjunction with your medical history and symptoms to develop an appropriate treatment plan tailored to your specific needs.

Yes, it is possible for a person with normal test results to still have a primary immunodeficiency disorder. The diagnosis of these disorders often involves a combination of clinical evaluation, medical history, and additional tests beyond the Primary Immunodeficiency Work-Up-Basic.

Lifestyle changes, such as maintaining a healthy diet, exercising regularly, and practicing good hygiene, can support overall immune health but may not be sufficient to correct primary immunodeficiency disorders. Treatment options for these disorders may include immunoglobulin replacement therapy, medications to manage symptoms, and, in some cases, stem cell transplantation. It is essential to work closely with a healthcare provider to develop an individualized treatment plan.

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