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Lab Test

Periodic Acid Schiff (PAS) Stain

The Periodic Acid Schiff (PAS) stain is a histology procedure used to detect polysaccharides such as glycogen, and mucosubstances such as glycoproteins, glycolipids and mucins in tissues. The PAS stain works by oxidizing the polysaccharides to form aldehyde residues. These residues then react with the Schiff reagent to give a purple/magenta color. It's particularly useful in diagnosing certain medical conditions, such as fungal infections and disorders affecting the liver, kidney, and lung tissues.


  • Profile Name: Periodic Acid Schiff (PAS) Stain
  • Sample Type: Bone marrow/ Blood/ Tissue Biopsy
  • Preparations Required: No special preparation is required for this test.
  • Report Time: 2 Days

Why is a Periodic Acid Schiff (PAS) stain done?

A PAS stain is performed to help diagnose various medical conditions, including glycogen storage diseases, fungal infections, Alport syndrome, and certain types of cancer.

Do I need to fast before this test?

No, fasting is not required for this test.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

The PAS stain test detects polysaccharides such as glycogen, and mucosubstances like glycoproteins, glycolipids, and mucins in tissue samples.

The frequency of this test depends on your doctor's recommendation and is usually guided by your symptoms and medical condition.

Normal values vary based on the specific tissue and structure being examined. Normal cells and tissues will show typical staining patterns, while abnormal or diseased tissues may show different patterns.

There are no specific precautions you need to take for this test. However, as a biopsy is involved, your healthcare team will provide guidance on care of the biopsy site.

There are no modifiable factors that can influence the results of this test.

Non-modifiable factors that can influence the test results include your genetic makeup and the presence of disease.

If your test results are abnormal, you should consult with your doctor, who can explain the results and discuss the next steps in your care.

The PAS stain itself is not risky. However, the tissue biopsy procedure used to obtain the tissue sample can carry minimal risks such as bleeding or infection.

Yes, conditions such as fungal infections, glycogen storage diseases, and some cancers can affect the test results.

No, medications do not typically affect the results of this test.

A positive PAS stain means that the tested substance (such as polysaccharides or mucosubstances) is present in the tissue sample.

Since this test is primarily diagnostic and used to detect the presence of certain substances in tissue samples, there is nothing specific you can do to improve your results.

Treatment depends on the underlying condition diagnosed through the test. Your doctor will discuss appropriate treatment options based on your specific condition and test results.

People with certain medical conditions, such as glycogen storage diseases, fungal infections, or specific cancers, are more likely to have a positive PAS stain.

No specific preparation is required for this test. However, it's important to follow your doctor's instructions regarding care of the biopsy site, if applicable.

Consistently positive test results could indicate an ongoing or chronic condition. It's crucial to discuss this with your doctor, who can provide further guidance.

The PAS Stain test is a highly reliable method for detecting certain substances in tissue samples when performed in a certified lab.

Your doctor may order additional tests depending on the suspected condition, such as microbiological tests for a suspected infection, or further histopathological studies for suspected cancer.

Understanding your test results can provide important insights into your health. Always discuss with your doctor any questions or concerns you may have about your test results or medical condition.

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