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Osmotic Fragility

The Osmotic Fragility Test (OFT) is an essential blood test used to evaluate disorders that affect the functioning and structure of red blood cells (RBCs), most notably hereditary spherocytosis. This diagnostic method exposes RBCs to changing levels of saline solution, showing insights on their vulnerability to rupture or 'lyse' at different osmotic pressures.

  • Test NameOsmotic Fragility
  • Sample TypeBlood
  • Preparations RequiredNo specific preparations are necessary for this test.
  • Report Time3 days

Understanding the OFT is essential for taking an active role in your medical care. If the results are abnormal, indicating easy lysis of red blood cells, this may indicate the presence of diseases that weaken the RBC membrane, such as hereditary spherocytosis, thalassemia, and certain kinds of anemia. Consult a hematologist or primary care physician to evaluate the results in light of your symptoms and medical history. This proactive method allows for informed decision-making in the management of disorders affecting red blood cells.

Home Sample Collection Process

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Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

The Osmotic Fragility Test is crucial in diagnosing conditions that affect the strength and stability of red blood cell membranes, such as hereditary spherocytosis. It can also be useful in diagnosing other red blood cell disorders like thalassemia and certain types of anemia.

No, fasting is not required for the Osmotic Fragility Test.

This test is typically ordered when a healthcare provider suspects a condition affecting red blood cell structure and function, often in cases of unexplained anemia, jaundice, or splenomegaly (enlargement of the spleen).

The Osmotic Fragility Test measures the susceptibility of red blood cells to rupture when exposed to varying concentrations of a saline solution, reflecting the strength and stability of the red blood cell membranes.

Normal values can vary depending on the laboratory conducting the test. Generally, normal red blood cells do not lyse until the saline concentration drops significantly.

OSMOTIC (RBC) FRAGILITY TEST, SODIUM HEPARIN WHOLE BLOOD
₹ 1000
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