Orotic Acid - Diagnostic Test, Price, Normal Range | Sprint Diagnostics Hyderabad

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₹ 3950


The orotic acid test is a diagnostic procedure primarily used to measure the level of orotic acid in the urine. This test plays a crucial role in diagnosing and monitoring inherited metabolic disorders, especially those involving the urea cycle such as Orotic Aciduria.

Orotic Acid is a compound naturally present in the body. It plays a crucial role in the biosynthesis of pyrimidines, which are essential components of DNA and RNA. In normal circumstances, orotic acid is produced and subsequently converted into other compounds in the body. However, certain genetic disorders can disrupt this process, leading to an accumulation of orotic acid in the body, which is then excreted in the urine. This test measures the levels of orotic acid in the urine to aid in the diagnosis of these disorders.

Test Name Orotic Acid - Diagnostic Test
Sample Type Urine
Preparations Required None
Report Time 4 days
Price in Hyderabad ₹ 3950

Why is the Orotic Acid test done?

The Orotic Acid test is primarily used to detect inherited metabolic disorders such as Orotic Aciduria. In such conditions, an excess of orotic acid is present in the body, which is then excreted in the urine.

When should one get this test?

If a person is exhibiting symptoms of metabolic disorders like lethargy, failure to thrive, developmental delay, seizures, or has a family history of these disorders, an orotic acid test may be recommended.

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How is the test performed?

The test is performed on a urine sample. The patient is required to provide a sample, typically a 24-hour urine collection, which is then sent to a laboratory for analysis.

What does the test measure?

The test measures the concentration of orotic acid in the urine. High levels can indicate a metabolic disorder.

How often should this test be done?

The frequency of this test is typically determined by your healthcare provider, based on your symptoms, medical history, and the progression of any diagnosed metabolic disorder.

What are the normal values for this test?

Normal values can vary based on the lab performing the test. Your healthcare provider will interpret your results based on their knowledge of your health history and symptoms.

What precautions should be taken before and after the test?

Before the test, no specific preparation is required. After the test, follow your healthcare provider's instructions.

Which factors can affect the levels of Orotic Acid?

Factors such as diet, hydration, and certain medications can potentially affect orotic acid levels. Inform your healthcare provider of any medications or supplements you are taking.

What should one do in case of abnormal values?

In case of abnormal values, a further consultation with a medical geneticist or a metabolic disorders specialist may be required to confirm a diagnosis and guide treatment.

Is fasting required for this test?

No, fasting is generally not required for this test.

Can this test detect other metabolic disorders?

While this test is primarily used to detect disorders involving the urea cycle, abnormal results may suggest the need for further testing for other potential metabolic disorders.

Can lifestyle modifications impact the result of this test?

A healthy lifestyle is always beneficial. However, the levels of orotic acid are mainly influenced by metabolic processes that are often genetically determined.

Can this test be performed during pregnancy?

Yes, this test can be performed during pregnancy if deemed necessary by a healthcare provider.

How does the diet impact the orotic acid levels?

While your diet may affect the levels of many substances in your body, orotic acid levels are mostly determined by your body's metabolic processes and any genetic disorders that affect them.

Can medications influence the result of this test?

Certain medications may influence the levels of orotic acid. Always inform your healthcare provider of any medications you are taking.

Are there any risks associated with this test?

The test is generally safe and non-invasive, as it simply involves the collection of a urine sample.

Is the test accurate?

The accuracy of the test depends on the methodology used by the laboratory. However, it is generally considered to be a reliable test for diagnosing conditions associated with elevated orotic acid levels.

Does this test involve radiation exposure?

No, this test does not involve any radiation exposure as it is a biochemical analysis performed on a urine sample.

Does the result of this test confirm a diagnosis?

While an abnormal result can be indicative of certain conditions, further diagnostic tests may be necessary to confirm a diagnosis.

What if I have symptoms but my test results are normal?

If you have symptoms but your orotic acid levels are normal, your healthcare provider may recommend further testing to investigate other potential causes of your symptoms.

Can this test be performed on infants and children?

Yes, this test can be performed on individuals of all ages, including infants and children, especially if there are symptoms or a family history suggestive of a metabolic disorder.

Can I take the test if I have a urinary tract infection?

It's important to inform your healthcare provider if you have a urinary tract infection or any other urinary symptoms, as these could potentially affect the test results.

Is this test covered by insurance?

Coverage for this test will depend on your insurance policy. Please consult with your insurance provider for more information.

Does exercise affect the levels of orotic acid?

There is no direct evidence to suggest that exercise significantly impacts the levels of orotic acid.

What is the difference between orotic aciduria type I and type II?

Orotic aciduria type I is caused by a deficiency in the enzyme orotate phosphoribosyltransferase, while type II is caused by a combined deficiency of this enzyme and the enzyme orotidine 5'-phosphate decarboxylase. Both result in an accumulation of orotic acid in the body.

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