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NSE (Neuron Specific Enolase) - CSF

The NSE (Neuron Specific Enolase) test in cerebrospinal fluid (CSF) is a diagnostic tool often used to detect and monitor certain types of cancers and neurological disorders. Neuron Specific Enolase is a protein found in nerve cells and neuroendocrine cells and can be detected in the cerebrospinal fluid, blood, and other body tissues.


  • Test NameNSE (Neuron Specific Enolase) - CSF
  • Sample TypeCerebrospinal Fluid (CSF)
  • Preparations RequiredBefore taking this test, it is crucial to inform your doctor about any medications, supplements, or treatments you are currently undergoing.
  • Report Time3 days

NSE levels may be elevated in several conditions, including small cell lung cancer, neuroblastoma, malignant melanoma, and certain types of brain injury or neurological disorders. Therefore, the test is used to monitor the progression and treatment response of these conditions.

Home Sample Collection Process
1
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Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

An NSE - CSF test may be recommended if you have been diagnosed with a neurological disorder or certain types of cancers, including small cell lung cancer, neuroblastoma, or malignant melanoma. It helps in monitoring disease progression and response to treatment.

The test requires a sample of cerebrospinal fluid (CSF), collected through a procedure called a lumbar puncture or spinal tap. In this procedure, a needle is inserted into your lower back to extract the fluid.

The risks associated with a lumbar puncture procedure include discomfort or pain at the site of the needle insertion, headache, bleeding, or in rare cases, infection. It is advisable to discuss the risks and benefits with your healthcare provider before the procedure.

A positive result, indicating elevated levels of NSE in the CSF, can suggest the presence or progression of certain cancers or neurological disorders. However, the result should be interpreted in conjunction with other tests and clinical symptoms.

Yes, the test can be performed on individuals of any age, but the doctor will take special precautions while performing a lumbar puncture on a child.

NSE levels in CSF can provide valuable information on the effectiveness of treatment for certain cancers or neurological disorders. Changes in NSE levels can indicate whether a treatment is working or if a change in treatment approach is needed.

Yes, elevated NSE levels can also be seen in cases of traumatic brain injury, stroke, or severe bacterial infections. Therefore, results should be interpreted in the context of the overall clinical picture.

The NSE - CSF test is generally accurate when performed in a qualified laboratory. However, results may vary based on factors such as the exact method used, the individual’s health, and the presence of other substances in the CSF.

The typical turnaround time for the NSE - CSF test is between 5 and 7 days, but it can vary depending on the lab.

There are no specific dietary restrictions for this test, but it’s always a good idea to follow the specific instructions provided by your healthcare provider or the lab.

Yes, there are other tests that can be used to monitor neurological disorders or cancers. For example, tests for other biomarkers, such as CEA (Carcinoembryonic antigen), AFP (Alpha-fetoprotein), and CA 19-9 (Carbohydrate antigen 19-9), may be used depending on the type of cancer or neurological disorder. However, these tests may not be as specific or sensitive as the NSE - CSF test for certain conditions. Always discuss with your doctor the most suitable testing options for your specific situation.

Before the procedure, your doctor may advise you to stop taking certain medications, particularly blood thinners, to reduce the risk of bleeding. You should also arrange for someone to drive you home afterwards, as you may feel a bit dizzy or faint. It's generally recommended to drink plenty of fluids before and after the procedure to help prevent headaches.

After the procedure, you should take it easy for the rest of the day. You might experience some discomfort or mild pain at the puncture site, which can be relieved by over-the-counter pain medication. If you experience severe headache, persistent pain, fever, or notice any signs of infection at the puncture site, contact your healthcare provider immediately.

While the NSE - CSF test is generally reliable, it is not definitive. Elevated levels of NSE in CSF can occur in various conditions and may not necessarily indicate the presence or progression of cancer or a neurological disorder. Therefore, the test results must be interpreted in conjunction with other diagnostic tests and clinical symptoms.

Generally, the NSE - CSF test is not used as a screening tool due to its lack of specificity. It is primarily used to monitor patients who have been diagnosed with certain types of cancers or neurological disorders.

Yes, the NSE - CSF test result can be influenced by factors such as the method used for the test, the individual's overall health, and the presence of other substances in the CSF. It is essential to discuss any possible interferences or limitations with your healthcare provider.

No, the NSE - CSF test requires a sample of cerebrospinal fluid, which is collected through a lumbar puncture procedure. This procedure should be performed by a trained healthcare professional in a clinical setting.

Normal ranges can vary among different labs, and it's best to discuss specific numbers with your healthcare provider. However, higher than normal levels of NSE in CSF could indicate a possible neurological disorder or cancer.

Other tests might include complete blood count (CBC), chemistry panel, tumor marker tests, imaging studies such as MRI or CT scan, and other specific tests depending on the suspected diagnosis.

The NSE - CSF test is generally not used as a prognostic tool. However, in some cases, it may provide information on the severity or progression of a disease, which can be useful in guiding treatment decisions. Always discuss the implications of your test results with your healthcare provider.

The NSE - CSF test is a valuable tool for monitoring the progression and treatment response in certain types of cancers and neurological disorders. However, the test results should always be interpreted in conjunction with other diagnostic tests and the overall clinical picture. It is always best to discuss any concerns or questions with your healthcare provider.

NSE (Neuron Specific Enolase) - CSF
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