NK Cells Index Analysis - Endometrium Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : There are no specific instructions required for this test. Your healthcare provider will collect the endometrial tissue sample during a scheduled appointment.

₹ 3500


NK Cells Index Analysis is a diagnostic test focused on examining the population of Natural Killer (NK) cells in the endometrial tissue. Natural Killer cells are a type of immune cell that plays a crucial role in the body's defense against viruses and cancer. They are also involved in the complex process of embryo implantation, making them a point of interest in the field of reproductive medicine.

The NK Cells Index Analysis test uses a sample of tissue from the endometrium - the lining of the uterus. This lining is where the implantation of an embryo occurs during a successful pregnancy. By examining the population of NK cells in this tissue, doctors can gain insights into potential fertility issues, recurrent miscarriage, or repeated IVF failure.

An endometrial biopsy is performed to obtain the tissue sample for this test. It's a procedure carried out in a healthcare provider's office, and involves the insertion of a thin, flexible tube through the cervix and into the uterus. The sample of endometrial tissue is then retrieved through this tube. Following the collection, the sample is processed in a lab to evaluate the number and activity of NK cells present.

Test Name NK Cells Index Analysis - Endometrium
Sample Type Tissue
Preparations Required There are no specific instructions required for this test. Your healthcare provider will collect the endometrial tissue sample during a scheduled appointment.
Report Time 4 days
Price in Hyderabad ₹ 3500

What is an NK Cells Index Analysis?

An NK Cells Index Analysis is a diagnostic test that examines the population of Natural Killer cells in the endometrial tissue. The results of this test can provide valuable insights into fertility issues.

What does the NK Cells Index Analysis test involve?

The test requires an endometrial biopsy, which involves the retrieval of a small sample of endometrial tissue. This sample is then analyzed in the lab to determine the number and activity of NK cells present.

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How should I prepare for the test?

No special preparation is required for this test. You will likely be given specific instructions by your healthcare provider regarding any precautions to take before and after the biopsy.

How is the endometrial biopsy performed?

The endometrial biopsy is performed by inserting a thin, flexible tube through the cervix and into the uterus. A sample of endometrial tissue is then collected through this tube.

Is the endometrial biopsy painful?

You may experience some discomfort during the biopsy, similar to menstrual cramps. Your healthcare provider may suggest taking over-the-counter pain medication prior to the procedure to help alleviate any potential discomfort.

How long will it take to get the results?

The typical turn-around time for results is 3-5 days. However, this may vary depending on the laboratory's workflow.

What do the results mean?

An increase in the number or activity of NK cells in the endometrium could indicate an immune response that may interfere with embryo implantation. This can be associated with fertility issues, recurrent miscarriage, or repeated IVF failure.

What happens if my NK cell levels are high?

If your NK cell levels are high, your healthcare provider will discuss the results with you and may suggest further tests or treatments based on your individual circumstances.

What happens after the test?

After the test, you may experience slight cramping or spotting. These symptoms should resolve within a day or two. If you experience severe pain, heavy bleeding, or fever, contact your healthcare provider immediately.

Can the test result be influenced by other factors?

Yes, factors such as current infection, recent surgery, or certain medications may affect the results of the test. It's important to let your healthcare provider know about any recent health changes before the test.

Is there any risk involved in this test?

The biopsy procedure carries a small risk of infection or injury to the uterus. However, it's generally considered a safe procedure when performed by an experienced healthcare provider.

Can I return to my normal activities after the test?

Yes, you should be able to return to your normal activities soon after the test. However, you may wish to take it easy for the rest of the day, particularly if you've had sedation.

Is the NK Cells Index Analysis test a definitive diagnosis for fertility issues?

While the NK Cells Index Analysis test can provide valuable insights, it is not a definitive diagnosis for fertility issues. Your healthcare provider will consider your test results along with other information to provide a comprehensive assessment.

How is an abnormal NK cell activity treated?

Treatments for abnormal NK cell activity vary and depend on the individual's overall health, medical history, and fertility goals. Potential treatments could include medication, lifestyle changes, or assisted reproductive techniques.

Can lifestyle changes improve my NK cell activity?

While a healthy lifestyle can support overall immune function, it's unclear whether specific lifestyle changes can directly improve NK cell activity. It's best to discuss this with your healthcare provider.

Are there alternatives to the NK Cells Index Analysis test for diagnosing fertility issues?

Yes, there are various tests available to diagnose fertility issues. These could include hormone level tests, imaging studies like ultrasound, or other specific tests depending on the suspected underlying issue. Your healthcare provider will decide the best approach based on your individual circumstances.

Will I need to repeat the test?

Whether you need to repeat the test will depend on your results, your symptoms, and your healthcare provider's judgement. If your test shows high NK cell activity, your doctor may recommend a follow-up test after a period of treatment or lifestyle changes.

Is the NK Cells Index Analysis test covered by insurance?

Coverage for the NK Cells Index Analysis test will depend on your health insurance provider and plan. It's best to contact your insurance company to inquire about coverage before having the test.

Can I take this test while on my period?

Ideally, the endometrial biopsy should not be performed while you're menstruating as it could interfere with the test results. Your healthcare provider will guide you on the best timing for the test.

What does it mean if my NK cell levels are normal but I'm still having fertility issues?

If your NK cell levels are normal, but you're still experiencing fertility issues, it suggests that there may be other underlying causes. Fertility issues can result from various factors, including hormonal imbalances, structural abnormalities, age, or male factor infertility. Your healthcare provider will work with you to identify other possible causes and recommend appropriate tests or treatments.

Are there any side effects of the treatment for high NK cell activity?

Treatments for high NK cell activity can have side effects, which will depend on the specific treatment used. Medications, for example, can have side effects ranging from minor, such as nausea or headaches, to more serious ones. It's important to discuss potential side effects with your healthcare provider before starting treatment.

Can high NK cell activity affect my chances of successful IVF?

Yes, high NK cell activity in the endometrium may affect embryo implantation and can potentially influence the success of IVF. Some research suggests that certain treatments for high NK cell activity could improve IVF outcomes, but more studies are needed to confirm these findings.

Can diet or supplements affect NK cell activity?

While a healthy diet is important for overall health and wellbeing, it's unclear whether specific foods or supplements can directly influence NK cell activity in the endometrium. Always consult with your healthcare provider before starting any new diet or supplement regimen.

Can stress influence my NK cell levels?

Chronic stress can impact the immune system as a whole, potentially influencing NK cell activity. However, the relationship between stress and NK cell levels in the endometrium is not entirely clear. Practicing stress management techniques such as mindfulness, yoga, or other relaxation exercises may have a positive impact on overall health and wellbeing.

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