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NEFA (Non-Esterified Fatty Acids) - Serum

NEFA, also known as Non-Esterified Fatty Acids or Free Fatty Acids (FFAs), are molecules released into the bloodstream from the breakdown of lipids (fat cells). The NEFA test measures the level of these fatty acids in the blood serum.

  • Test NameNEFA (Non-Esterified Fatty Acids) - Serum
  • Sample TypeBlood
  • Preparations RequiredNo specific fasting, preparation, or restrictions are needed for this test. Follow your doctor's advice and maintain your regular dietary and medication routines unless directed otherwise.
  • Report Time2 Days

Fatty acids serve many essential roles in the body, including providing energy. In between meals, when glucose levels drop, fatty acids become a major energy source. In normal health, fatty acids are stored as triglycerides in fat cells and are released and metabolized as needed. However, if there's an imbalance, and too many fatty acids are released and not fully metabolized, high levels can circulate in the blood.

Measurement of NEFA in serum can provide essential information regarding a person's metabolic state and the function of certain hormones such as insulin. NEFA levels are often assessed in the context of diabetes, obesity, metabolic syndrome, and various other metabolic disorders.

Home Sample Collection Process

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Sample Collection by Phlebotomist
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Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

NEFA test helps in understanding your body's metabolic state and is particularly relevant if you have a metabolic disorder, diabetes, or are obese. It measures the amount of free fatty acids in your blood, providing important information about how your body breaks down fats for energy.

No special preparation is required for the NEFA test. You should maintain your regular diet and medication schedules unless directed otherwise by your healthcare provider.

High NEFA levels can indicate that your body is not metabolizing fat correctly. This can be a sign of conditions such as metabolic syndrome, obesity, or diabetes.

The test is performed using a blood sample, which is drawn from a vein in your arm using a sterile needle.

You may feel a minor prick when the needle is inserted. Most people do not find the procedure painful.

The risks associated with a blood draw are minimal but may include slight pain or bruising at the site of needle insertion.

High NEFA levels may indicate the need for lifestyle changes, including dietary modification and increased physical activity. In some cases, medication may be required. Always consult with your healthcare provider for personalized advice.

The turnaround time varies but generally, you can expect results within a few days.

Yes, no specific fasting is required before the NEFA test. However, always follow the specific instructions provided by your healthcare provider.

Your healthcare provider may order additional tests if your NEFA levels are abnormal to further investigate potential metabolic disorders. These could include glucose tests, lipid profile, and others.

Yes, certain medications can affect NEFA levels. Always inform your healthcare provider of any medications you are taking.

Normal NEFA levels can vary, and the range will typically be provided with your test results. What is considered "normal" can depend on many factors, including age, sex, and overall health.

Yes, stress can trigger the release of hormones that cause fat cells to break down, which can lead to an increase in NEFA levels.

Yes, NEFA levels can fluctify throughout the day based on factors like eating, exercise, and stress. They're often higher in the morning and lower in the afternoon and evening.

While high NEFA levels can be associated with metabolic syndrome and diabetes, which are risk factors for heart disease, the NEFA test alone cannot diagnose heart disease. However, it can be a useful piece of the overall puzzle in understanding your cardiovascular risk.

Besides metabolic syndrome, diabetes, and obesity, high NEFA levels can also suggest other conditions such as hypothyroidism, severe stress, and certain types of starvation or malnutrition.

Consumption of high-fat foods can increase NEFA levels in your blood, as can excessive alcohol intake. A balanced diet rich in fruits, vegetables, lean proteins, and whole grains can help regulate NEFA levels.

Yes, physical activity can help regulate NEFA levels. During exercise, your body utilizes fatty acids for energy, which can lead to lower NEFA levels in the blood.

Yes, smoking can lead to elevated NEFA levels. It can cause an increase in lipolysis, a process where triglycerides in fat cells are broken down into glycerol and NEFAs.

Insulin plays a key role in regulating NEFA levels by inhibiting lipolysis. When insulin levels are low, as in type 1 diabetes, or when the body doesn't respond properly to insulin, as in type 2 diabetes, this can lead to elevated NEFA levels.

NEFA (Non Esterified Fatty Acids) - serum
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