Myeloproliferative Neoplasms Reflex Test in Hyderabad

Patient Preparing : No special preparation is required for this test.

₹ 14450


The MPN Reflex test is a comprehensive genetic analysis that includes mutation screening of JAK2V617F, JAK2 Exon 12, CALR, and MPL, which are known to be associated with MPNs. This testing is important for accurate diagnosis, prognosis, and management of these disorders.

MPNs are a diverse set of blood diseases characterised by an increase in the production of red blood cells, white blood cells, or platelets. The MPN Reflex test analyzes the mutations in the JAK2, CALR, and MPL genes, which are associated with the majority of cases of MPNs. These mutations are involved in cell growth and division, and their abnormal functioning leads to excessive proliferation of cells in the bone marrow. Understanding the genetic basis of MPNs through this test is crucial for precise diagnosis, risk stratification, and guiding therapeutic decisions.

As one of the best diagnostic services in Hyderabad, Sprint Diagnostics is known for its commitment to providing accurate and reliable results. If you are in Hyderabad and looking for the best MPN Reflex testing near you, Sprint Diagnostics is a trusted option to consider. Taking prompt action, guided by the expertise of specialists, is key to effectively managing MPNs and ensuring the best possible outcomes for individuals facing these blood disorders.

Test Name Myeloproliferative Neoplasms (MPN) Reflex: JAK2V617F, JAK2 Exon 12, CALR, and MPL
Sample Type blood
Preparations Required No special preparation is required for this test.
Report Time refer individual test
Price in Hyderabad ₹ 14450

Frequently Asked Questions

1. Why is the MPN Reflex test important?

This test is important for the diagnosis and management of MPNs. It helps in distinguishing between different types of MPNs, understanding the prognosis, and guiding the choice of treatment.

2. What is the role of MPL mutations in MPNs?

MPL mutations can activate the thrombopoietin receptor, causing an increased production of blood cells, particularly platelets. This is associated with certain MPNs like Essential Thrombocythemia and Primary Myelofibrosis.

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3. How is the MPN Reflex test performed?

The MPN Reflex test is performed using a blood or bone marrow sample. The sample is analyzed in the laboratory to detect the presence of mutations in the JAK2, CALR, and MPL genes.

4. Is fasting required for the MPN Reflex test?

No, fasting is not required for this test.

5. What should I do if the test results are abnormal?

If the results of the MPN Reflex test are abnormal, it is important to consult your doctor to discuss the implications and to determine the appropriate course of action for management or treatment.

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