Myeloma Cytogenetics with CD138 Magnetic Bead Enrichment Test, Price, Normal Range | Sprint Diagnostics Hyderabad
Patient Preparing : No special preparation is required for this test.
Home Sample Collection
What is FISH analysis, and how does it complement karyotyping?
Fluorescence In Situ Hybridization (FISH) involves using fluorescent probes to target specific DNA sequences on chromosomes. It is highly sensitive and can detect even small genetic changes, making it a complementary technique to karyotyping.
What is del17p and its significance in multiple myeloma?
Del17p refers to the deletion of a part of the short arm of chromosome 17. This genetic abnormality is associated with more aggressive disease and resistance to certain therapies.
How does IGH breakapart affect multiple myeloma?
IGH breakapart refers to rearrangements involving the immunoglobulin heavy chain gene on chromosome 14. These rearrangements can drive the development and progression of multiple myeloma.
Why are translocations t(4;14) and t(14;16) significant?
Translocations t(4;14) and t(14;16) are genetic abnormalities involving exchanges between chromosomes 4 and 14, and 14 and 16, respectively. These are associated with high-risk multiple myeloma and can influence treatment decisions.
How is the sample collected for this test?
A bone marrow aspiration procedure is used to collect the sample. This involves inserting a needle into the bone, usually the hip bone, to extract a small amount of bone marrow.
How will the results of this test influence my treatment?
The results can help your doctor to assess the risk level of the disease and customize the treatment plan accordingly. Certain genetic abnormalities may require more aggressive treatments.
What are the treatment options for multiple myeloma?
Treatment options include chemotherapy, targeted therapy, immunotherapy, stem cell transplantation, and supportive care for managing symptoms and improving quality of life.
Are there any risks associated with the bone marrow aspiration procedure?
There is a small risk of infection, bleeding, or bruising at the needle site. The healthcare team will take precautions to minimize these risks.
Can lifestyle changes impact the progression of multiple myeloma?
Although lifestyle changes can’t cure multiple myeloma, maintaining a healthy lifestyle can help improve overall health and might positively influence the response to treatment.
Is multiple myeloma curable?
Currently, multiple myeloma is not considered curable, but it is treatable. Advances in treatment have significantly improved the quality of life and survival rates for patients with multiple myeloma.
How often should this test be done?
Myeloma Cytogenetics with CD138 magnetic bead enrichment is usually done at diagnosis to help establish a treatment plan. Your doctor may also recommend repeat testing if there is a change in your condition or to monitor the response to treatment.
Which doctor should I consult if I have abnormal results?
Consult a hematologist or oncologist specializing in blood cancers if you have abnormal results indicative of multiple myeloma.
What is the prognosis for multiple myeloma with chromosomal abnormalities?
The prognosis for multiple myeloma varies depending on the chromosomal abnormalities present. Certain abnormalities such as del17p are associated with a poorer prognosis, whereas others may have a more favorable outcome.
Understanding the genetic makeup of multiple myeloma is crucial for personalized treatment strategies. Myeloma Cytogenetics with CD138 magnetic bead enrichment is an advanced diagnostic technique that provides valuable information on the genetic abnormalities in plasma cells. The insights gained through this testing can play a significant role in risk stratification, selecting the most appropriate therapeutic approach, and monitoring the disease. Work closely with your doctor to understand the results and implications for your specific condition.
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