Myeloma Cytogenetics - Karyotyping and FISH Analysis Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is required for this test.

₹ 16000

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What is the significance of del17p in multiple myeloma?

Deletion of the short arm of chromosome 17 (del17p) is associated with a high-risk form of multiple myeloma. It is often associated with resistance to standard treatments and a poor prognosis.

What is IGH breakapart, and why is it important?

IGH breakapart refers to rearrangements involving the immunoglobulin heavy chain gene (IGH) on chromosome 14. These rearrangements can play a significant role in the development of multiple myeloma and can affect the patient’s response to treatment.

What is the role of translocation t(4;14) in multiple myeloma?

Translocation t(4;14) involves an exchange of genetic material between chromosomes 4 and 14. This abnormality is associated with a more aggressive form of multiple myeloma and may necessitate specific targeted therapies.

What does translocation t(14;16) indicate?

Translocation t(14;16) is another chromosomal abnormality in which parts of chromosomes 14 and 16 are exchanged. Like t(4;14), this translocation is associated with a high-risk form of multiple myeloma.

How is the sample for Myeloma Cytogenetics collected?

A bone marrow aspiration procedure is used to collect the sample. This involves inserting a needle into the bone (usually the hip bone) to extract a small amount of bone marrow.

Does this test require any special preparation?

No special preparation is required for Myeloma Cytogenetics testing. However, it’s important to inform your doctor of any medications or supplements you are taking.

What do the results of Myeloma Cytogenetics mean for my treatment?

The results can influence the course of treatment. Certain chromosomal abnormalities may indicate that more aggressive treatment is needed, while others may suggest a good response to standard therapies.

How often should I get this test?

Myeloma Cytogenetics is usually performed at the time of diagnosis to help establish a treatment plan. Your doctor may recommend repeating the test if there is a change in your condition or to monitor the response to treatment.

Are there any risks associated with the bone marrow aspiration procedure?

As with any procedure involving a needle, there is a small risk of infection, bleeding, or bruising at the site where the needle was inserted.

Can lifestyle changes impact the progression of multiple myeloma?

While lifestyle changes cannot cure multiple myeloma, maintaining a healthy lifestyle can help improve overall health and may positively influence how well you respond to treatment.

What are the treatment options for multiple myeloma?

Treatment options for multiple myeloma include chemotherapy, targeted therapy, immunotherapy, stem cell transplant, and supportive care to manage symptoms.

Which doctor should I consult if I have been diagnosed with multiple myeloma?

It’s important to consult a hematologist or oncologist who specializes in the treatment of blood cancers, including multiple myeloma.

Is multiple myeloma curable?

As of now, multiple myeloma is not considered curable, but it is treatable. Advances in treatment have significantly improved the quality of life and survival rates for multiple myeloma patients.

Multiple myeloma is a complex disease with a variety of genetic abnormalities. Myeloma Cytogenetics, involving Karyotyping and FISH analysis, is crucial in understanding the genetic basis of the disease. This testing plays a critical role in diagnosis, risk stratification, and guiding therapy. If you or a loved one has been diagnosed with multiple myeloma, it’s essential to understand the value of cytogenetic testing and work closely with your doctor to develop a personalized treatment plan.

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