Myelin Basic Protein -CSF Test Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparations required for this test.

₹ 7500


Myelin Basic Protein (MBP) in Cerebrospinal Fluid (CSF) is a diagnostic test used primarily to assist in the diagnosis of neurological disorders, particularly those associated with the destruction of the myelin sheath, the protective coating surrounding nerve fibers. The test is most frequently used in the diagnosis and management of Multiple Sclerosis (MS), a chronic disease that attacks the central nervous system.

The MBP is a major constituent of the myelin sheath of nerves. During a disease episode, the myelin sheath can be damaged, causing MBP to be released into the CSF. Elevated levels of MBP in the CSF can indicate active disease, while normal or low levels can suggest remission or absence of disease.

It’s crucial to understand that while the test is a powerful tool in the diagnosis and management of neurological disorders, it is not definitive. It is typically used alongside other tests and examinations, and the results should always be interpreted in the context of the clinical presentation of the individual.

Test Name Myelin Basic Protein (MBP) - CSF: A Comprehensive Guide
Sample Type CSF
Preparations Required No specific preparations required for this test.
Report Time 4 days
Price in Hyderabad ₹ 7500

What is the process of the test?

The test requires a lumbar puncture (spinal tap) to collect a sample of cerebrospinal fluid. This procedure involves inserting a needle into the lower back to extract fluid. The sample is then analyzed in a laboratory for MBP.

Is the test painful?

The lumbar puncture procedure may cause some discomfort. An anesthetic is typically used to numb the area and minimize pain.

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How should I prepare for the test?

There are no special preparations necessary for the MBP test. However, you should discuss any medications you are taking with your doctor as they may affect the results.

What does a high MBP level mean?

A high level of MBP in the CSF can indicate damage to the myelin sheath of nerves, often seen in diseases such as Multiple Sclerosis.

Can the test be used to monitor the progress of my disease?

Yes, the MBP test can be used to monitor disease progression and the effectiveness of treatment in some patients.

Can the test be used to diagnose other neurological conditions?

While the MBP test is most frequently used in the diagnosis and management of MS, it can also be used in the diagnosis of other conditions involving myelin destruction.

What is the cost of the test?

The cost of the test can vary and it is best to contact your healthcare provider or the testing facility for the most accurate information.

Can this test predict the severity of my disease?

The level of MBP can be correlated with disease activity, but it is not a definitive measure of severity. The results should always be interpreted in the context of the clinical presentation.

What if I have a normal MBP level but still have symptoms?

A normal MBP level does not rule out neurological diseases, as the test is not 100% sensitive. Other diagnostic tests and clinical evaluations are necessary to confirm a diagnosis.

Can this test be done during pregnancy?

Yes, this test can be done during pregnancy if deemed necessary by your healthcare provider.

Is the test covered by insurance?

Coverage for the MBP test will depend on your insurance provider. It's advisable to check with them for specific details.

Can the test be done on a child?

Yes, the test can be done on a child if clinically indicated, but always under the guidance of a healthcare provider.

Is there any risk associated with the test?

The lumbar puncture procedure may have some risks, including headache, infection, or bleeding. It's important to discuss these risks with your healthcare provider.

Can the MBP test result in a false positive or negative?

While the MBP test is highly accurate, there is a small chance of false positives or negatives. Factors such as recent steroid use can affect the results.

What should I do after the test?

After the test, it's advisable to rest and avoid strenuous activities. Any test results should be discussed with your healthcare provider who will advise on the next steps.

How accurate is the Myelin Basic Protein test?

The accuracy of the MBP test in detecting demyelinating diseases like MS is high, however, it is not the only test used for diagnosis. The results are generally used in conjunction with other tests and clinical evaluations for a comprehensive diagnosis.

Is there any alternative to this test?

While the MBP test is a key component in diagnosing and monitoring MS and similar conditions, there are other tests used in conjunction, like the oligoclonal banding test, MRI scans, and other neurological evaluations.

Can medications affect the result of the MBP test?

Certain medications may affect the results of the MBP test, particularly those used in the treatment of MS and similar conditions. It's important to discuss all medications, both prescription and over-the-counter, with your healthcare provider prior to testing.

Can the test detect a relapse in my condition?

The MBP test can indicate a flare-up of disease activity if MBP levels rise in the CSF, suggesting an increase in myelin damage. It's important to understand that not all flare-ups may cause symptoms, and not all symptoms may be associated with elevated MBP.

How often should this test be done?

The frequency of the MBP test depends on individual circumstances, including the type and severity of your condition, your response to treatment, and your healthcare provider's recommendations. This test is not typically done routinely but used as needed to evaluate disease activity.

Is there any age restriction for this test?

There's no age restriction for the MBP test. It can be performed on individuals of all ages, from infants to older adults, depending on the clinical scenario.

What factors can affect the test results?

In addition to medications, other factors can potentially affect the MBP test results, including the technique used for lumbar puncture, handling and storage of the CSF sample, and laboratory techniques.

Why is it necessary to examine MBP in CSF?

The CSF surrounds your brain and spinal cord. Analyzing MBP in CSF can provide crucial information about diseases that affect the nervous system because changes in the brain or spinal cord often cause changes in the CSF.

Can an infection affect the test result?

Certain infections of the nervous system can cause an increase in MBP in the CSF, potentially affecting test results. It's crucial to inform your healthcare provider if you have an ongoing infection or have recently recovered from one.

Can this test be used to confirm a diagnosis of MS?

The test contributes valuable information, but a diagnosis of MS is not based on a single test result. It's typically determined by a combination of clinical evaluations, imaging studies, and various laboratory tests, including the MBP test.

Are there any side effects after the lumbar puncture procedure?

Some people may experience side effects such as headaches, back pain, or minor bleeding at the puncture site. In rare cases, more serious complications can occur. You should discuss potential side effects with your healthcare provider.

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