Measles (Rubeola) IgG Antibodies - CSF

A sample of CSF is collected by a procedure known as lumbar puncture or spinal tap. It involves inserting a thin needle between two vertebrae in your lower back to withdraw a small amount of CSF.

The presence of measles-specific IgG antibodies in the CSF indicates a central nervous system infection with the measles virus. The absence of these antibodies suggests that the symptoms are not caused by a measles infection in the central nervous system.

A lumbar puncture is generally safe but can cause side effects such as headache, infection, or bleeding. Your doctor will explain all potential risks prior to the procedure.

Treatment involves managing symptoms and may include antiviral medications, steroids to reduce inflammation, and medications to control seizures or other symptoms.

You should follow your doctor's instructions regarding food and drink before the test.

IgM antibodies appear soon after infection while IgG antibodies appear later and remain in the body long-term. Detecting IgG antibodies in the CSF can suggest a past or ongoing measles infection in the central nervous system.

Measles can be prevented with the measles-mumps-rubella (MMR) vaccine, which is part of the routine vaccination schedule for children.

No, there is no specific antiviral therapy for measles. Treatment is focused on relieving symptoms and supporting the body's immune response.

Yes, adults can get measles if they're not vaccinated.

If you suspect you or your child may have measles, seek medical attention immediately. Early diagnosis and treatment can help manage the symptoms and prevent complications.

It's rare, but possible. Most people who have had measles become immune for life.

Measles is highly contagious. It can be spread through direct contact with an infected person or through the air when an infected person coughs or sneezes.

The prognosis varies, depending on the severity of the infection and the patient's overall health. Early diagnosis and treatment can improve the outcome.

Recovery times vary. Some people may recover in a few weeks, while others may need months. Some neurological effects may be permanent.

Yes, the presence of IgG antibodies in the CSF can indicate a past or ongoing measles infection in the central nervous system.

Direct detection of the measles virus is difficult and is usually not done in clinical practice. The body's immune response, as indicated by the presence of specific antibodies, is generally used to diagnose the infection.

If measles is suspected, tests for measles-specific IgM antibodies in the blood may also be done. In certain situations, molecular tests such as PCR can be used to detect the virus directly.

If you or a family member has measles, it's important to avoid contact with others, especially those who are unvaccinated or have a weakened immune system. Regular hand hygiene and respiratory etiquette (covering mouth and nose when coughing or sneezing) are also crucial.

Yes, the measles vaccine can provide some protection if given within 72 hours of exposure to the virus.