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Lab Test

Manganese Urine - 24 Hours

The 24-hour urine manganese test is a useful tool to assess manganese exposure and toxicity. Manganese is a trace mineral required by the body in small amounts for normal metabolic processes. However, overexposure or excessive accumulation of manganese in the body can lead to health complications, most notably neurological problems. This test measures the amount of manganese excreted in the urine over a 24-hour period.

  • Profile Name: Manganese Urine - 24 Hours
  • Sample Type: Urine
  • Preparations Required: You will be asked to collect all urine passed in a 24-hour period. Detailed instructions for the collection process will be provided.
  • Report Time: 2 Days

While necessary for health in small amounts, manganese can be harmful in excessive quantities. It is found naturally in the environment and in a variety of foods, and it is also used in industrial settings. Exposure to high levels of manganese, typically due to occupational exposure, can cause manganism, a condition with symptoms similar to Parkinson's disease.

Home Sample Collection Process

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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Download Reports
Frequently Asked Questions

This test is used to detect and monitor exposure to manganese. It may also be used to evaluate the effectiveness of treatment in people diagnosed with manganese poisoning.

This test requires a 24-hour urine collection. You will be asked to collect all urine passed over a 24-hour period in a special container provided by the laboratory.

A 24-hour urine sample gives a more accurate picture of manganese levels in the body than a single random urine sample. This is because it takes into account fluctuations in manganese excretion that occur throughout the day.

Symptoms of manganese toxicity can include tremors, clumsiness, sleep disturbances, mood changes, and reduced cognitive function. These symptoms are often similar to those seen in Parkinson's disease.

If the amount of manganese in the urine is higher than the reference range, it may indicate exposure to excessive amounts of manganese. Low levels can indicate a deficiency, though this is rare.

Preventing manganese toxicity primarily involves minimizing exposure to manganese, particularly in occupational settings. This can involve using personal protective equipment and ensuring adequate ventilation in work areas.

There are no significant risks associated with collecting a 24-hour urine sample.

You should follow your doctor's instructions regarding diet and medications before the test. Some foods and medications may affect the levels of manganese in your urine.

The primary treatment is to stop exposure to manganese. In severe cases, chelation therapy may be used to help remove manganese from the body.

People who work in industries where they are exposed to manganese dust or fumes are at the highest risk. This includes welding, mining, and manufacturing industries.

Yes, you can take this test during pregnancy. However, always inform your healthcare provider if you're pregnant, as this may affect the interpretation of the results.

Yes, liver disease and certain genetic disorders can affect the body's ability to process and excrete manganese, potentially leading to higher levels in the urine.

Yes, this test can detect low levels of manganese in the urine, which may indicate a deficiency. However, manganese deficiency is quite rare in humans.

If your manganese level is not normal, your healthcare provider might order additional tests, such as blood tests or a liver function test, to help determine the cause.

Manganese plays a role in many physiological processes, including protein, carbohydrate and cholesterol metabolism, and bone formation.

Yes, certain foods and medications can affect the levels of manganese in the urine. It's important to inform your healthcare provider about any dietary supplements, medications, and your diet before the test.

Certain medications can affect the test results. Be sure to inform your healthcare provider about all the medications and supplements you're currently taking.

Yes, the manganese urine test can be used to monitor the effectiveness of treatment for manganese toxicity and to ensure that levels are decreasing.

Yes, there can be false-positive or false-negative results with this test due to interference from certain medications or substances, or due to improper collection of the 24-hour urine sample.

Yes, it is possible to have elevated manganese levels without showing any symptoms, especially in the early stages of overexposure. Regular testing can help detect high levels before symptoms develop.

Symptoms of manganese deficiency can include weight loss, skin rash, low cholesterol levels, and impaired growth in children. However, manganese deficiency is quite rare in humans.

Yes, the test can detect a relapse of manganese toxicity by identifying increased levels of manganese in the urine.

Yes, it is possible to have poisoning from multiple heavy metals simultaneously, particularly if the person is exposed to an environment where several toxic metals are present.

Common sources of manganese exposure include occupational exposure (welding, mining, battery manufacturing), certain dietary supplements, and foods such as nuts, seeds, whole grains, and leafy green vegetables.

The frequency of testing depends on the level of exposure and the regulations in your specific industry. Your occupational health and safety advisor or healthcare provider will provide guidance based on your individual circumstances.

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