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Leptospira DNA Detection - PCR Urine

Leptospira DNA Detection - PCR Urine

Leptospirosis is a bacterial infection caused by the spiral-shaped bacteria from the Leptospira genus. It can be contracted when an individual comes in direct contact with urine from infected animals or with a urine-contaminated environment. The bacteria can enter the body through cuts and abrasions in the skin, or through the mucous membranes of the mouth, nose, and eyes. PCR (Polymerase Chain Reaction) is a highly sensitive method that detects the presence of bacterial DNA in urine and is used to diagnose Leptospirosis.

This test is particularly useful in detecting the bacteria during the later stages of the disease when it is more likely to be present in the urine.


  • Test NameLeptospira DNA Detection - PCR Urine
  • Sample TypeUrine
  • Preparations RequiredThere are no specific preparations required for this test. However, it’s advised to wear clean and loose clothing to make the sample collection process easier.
  • Report Time2 Days

What are the symptoms of Leptospirosis?

The symptoms of Leptospirosis can vary and might include high fever, chills, headache, muscle aches, vomiting, jaundice, red eyes, abdominal pain, rash, and sometimes, respiratory distress.

How is the Leptospira DNA detection in urine performed?

A urine sample is collected from the patient. In the laboratory, PCR technique is used to amplify and detect the DNA of the Leptospira bacteria, if present in the urine sample.

Home Sample Collection Process

1
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Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

Detection of Leptospira DNA in urine helps in the diagnosis of Leptospirosis, especially in the later stages of infection when the bacteria are excreted in urine. Early diagnosis and treatment are crucial to avoid complications.

Leptospirosis is typically treated with antibiotics. Severe cases might require hospitalization for supportive care to manage complications.

Avoiding contact with contaminated water or soil and taking preventive measures such as wearing protective clothing and practicing good hygiene can reduce the risk of infection. In some cases, prophylactic antibiotics might be recommended.

No, this test is not used for routine screening. It is usually ordered when a person has symptoms consistent with Leptospirosis and there is a possibility of exposure to the bacteria.

Blood tests for Leptospira antibodies, liver function tests, and kidney function tests may also be ordered to assess the infection and organ function.

There are no significant risks associated with providing a urine sample for this test. It is a non-invasive procedure.

It is important to inform your doctor about any medications or supplements you are taking, as they may affect the test results.

Individuals who have been exposed to a potentially contaminated environment, especially after floods or heavy rains, or those who are in close contact with animals should consider taking this test if they have symptoms of Leptospirosis.

Yes, Leptospirosis is a zoonotic disease, which means it can be transmitted between animals and humans.

If left untreated, Leptospirosis can lead to severe complications such as kidney damage, meningitis, liver failure, and respiratory distress. In severe cases, it can be fatal.

If the test is positive, it is important to follow the doctor’s instructions regarding medication and care. Avoid contact with others to prevent spreading the bacteria and ensure to maintain good personal hygiene.

Yes, a person can get Leptospirosis more than once as immunity from previous infections does not last for a lifetime.

Educating the community about the risks and symptoms of Leptospirosis, encouraging the use of protective gear, promoting good hygiene practices, and ensuring the proper disposal of animal waste can help control the spread of this disease.

In summary, the Leptospira DNA detection in urine is a valuable test for diagnosing Leptospirosis, particularly in the later stages of the disease. Early detection and treatment are critical for managing the infection effectively. If you suspect you have been exposed to Leptospira bacteria or are experiencing symptoms, it is essential to consult a doctor as soon as possible.

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