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LAP (Leukocyte Alkaline Phosphatase) Score

The LAP (Leukocyte Alkaline Phosphatase) Score test is a blood test that measures the activity of the alkaline phosphatase enzyme in white blood cells. Alkaline phosphatase is an enzyme found in various tissues, and its levels can fluctuate in response to certain diseases and conditions. The LAP score is often used to help in the diagnosis and monitoring of chronic myelogenous leukemia (CML), a type of cancer that affects the blood and bone marrow.

  • Test NameLAP (Leukocyte Alkaline Phosphatase) Score
  • Sample TypeBlood
  • Preparations RequiredNo specific preparation is needed for the test.
  • Report Time2 days

What is LAP Score?

LAP Score is a measure of the activity of the enzyme alkaline phosphatase within white blood cells. It can provide valuable information about the functioning and health of your bone marrow and is often used in the evaluation of blood disorders.

Why is the LAP Score test done?

The LAP Score test is primarily done to help diagnose chronic myelogenous leukemia (CML) and distinguish it from other conditions that cause a high white blood cell count. It can also be used to monitor the effectiveness of treatment in patients with CML.

Home Sample Collection Process

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Sample Collection by Phlebotomist
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Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

A low LAP Score may indicate chronic myelogenous leukemia or another bone marrow disorder. A high LAP Score can be seen in conditions such as polycythemia vera, leukemoid reaction, or certain infections. Normal scores vary, so it’s important to discuss the results with your doctor.

The test requires a blood sample, which is drawn through a needle from a vein in your arm.

The risks are minimal and are similar to those involved in a regular blood draw, such as slight pain, bleeding, or bruising at the puncture site.

Certain medications can affect the LAP Score. Inform your doctor about any medications, supplements, or treatments you are undergoing.

The frequency of the LAP Score test varies depending on the patient's condition and the doctor's assessment. It may be done as part of the diagnostic process and periodically during treatment.

Yes, infections can cause an increase in the LAP Score due to the increased production of white blood cells.

Various factors such as infections, medications, bone marrow disorders, and the body's response to stress can affect the LAP Score.

Serum alkaline phosphatase measures the total activity of the enzyme in the blood, while LAP Score specifically measures the enzyme's activity in white blood cells.

phosphatase in white blood cells is believed to be involved in the process of fighting infections and is a part of the body’s immune response.

Fasting is not required for the LAP Score test. You can have the test done at any time.

Normal values can vary, but typically range from 20 to 100 units per liter (U/L). However, what is considered normal can vary between laboratories.

If your LAP Score is abnormal, it is important to discuss the results with your doctor, who may recommend further testing or a referral to a specialist, such as a hematologist.

Yes, LAP Score can be a useful tool in monitoring the response to treatment in patients with CML, as changes in the LAP Score can reflect changes in the disease activity.

In conclusion, the LAP Score is a valuable diagnostic test that can provide critical information about the activity of alkaline phosphatase in white blood cells. It is primarily used in the diagnosis and monitoring of chronic myelogenous leukemia but can also be indicative of other conditions affecting the bone marrow or immune system. As with any medical test, it’s important to discuss the results and any subsequent steps with your doctor.

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