Karyotyping with Reflex FISH-5 Markers - Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : There are no specific preparations for the patient, as the sample is collected after a miscarriage or a termination procedure.

₹ 6900


Karyotyping with Reflex FISH using Products of Conception (POC) is a diagnostic procedure that involves analyzing chromosomes in the cells obtained from the tissue of a miscarriage or termination. Chromosomes carry our genetic material and any anomalies in their structure or number can cause development issues or pregnancy loss.

Fluorescence In Situ Hybridization (FISH) is combined with traditional karyotyping in this procedure. FISH utilizes fluorescent probes that attach to specific chromosome segments. This is particularly useful for detecting particular genetic abnormalities that might not be visible through conventional karyotyping.

This test is usually performed after a miscarriage or termination to understand if chromosomal abnormalities were a contributing factor.

Test Name Karyotyping (Products of Conception) with Reflex FISH - 5 Markers
Sample Type Products of Conception (tissue)
Preparations Required There are no specific preparations for the patient, as the sample is collected after a miscarriage or a termination procedure.
Report Time 21 days
Price ₹ 6900

What is the importance of Karyotyping using Products of Conception?

Karyotyping with POC helps in understanding the causes of a miscarriage or fetal abnormalities. It is vital for planning future pregnancies and assessing the risk of recurrence.

Is fasting required for this test?

No, fasting is not required as the sample is collected after a miscarriage or termination procedure.

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Is there any specific preparation needed for the test?

No specific preparation is required for the patient, as the sample is usually collected by healthcare professionals following a miscarriage or termination.

What information does this test provide?

This test analyzes the chromosomes in the products of conception and can identify abnormalities in their number or structure, which might have contributed to pregnancy loss or fetal abnormalities.

How often should this test be done?

This test is performed after a miscarriage or termination when there is a need to investigate the possible causes for future reference.

What are the normal values for this test?

Normal results would indicate 46 chromosomes with a typical structure. Any deviation from this should be evaluated and discussed with a doctor.

What precautions should be taken before and after the test?

There are no specific precautions for the patient as the sample is collected post-miscarriage or termination.

What factors affect the levels of chromosomes?

Chromosomal abnormalities can be inherited or occur spontaneously. They are not influenced by environmental factors and are usually random events.

Which doctor should be consulted in case of abnormal value?

In case of abnormal results, a geneticist or a doctor specializing in reproductive health and genetics should be consulted.

How is the sample for the test collected?

The sample is collected from the tissue after a miscarriage or termination by a healthcare professional.

Is this test safe?

As this test is performed on tissue collected after a miscarriage or termination, there are no risks associated with the collection procedure for the patient.

What happens if a chromosomal abnormality is detected?

If an abnormality is detected, genetic counseling will be provided. The information is vital for future family planning and understanding the risks in subsequent pregnancies.

How long does it take to receive the results?

It typically takes between 14 to 21 days to receive the results of this test.

Can Karyotyping using Products of Conception detect all genetic disorders?

No, while it is effective in detecting many chromosomal abnormalities, it may not detect all genetic disorders, especially those caused by mutations in a single gene.

What is the role of FISH in this test?

FISH, or Fluorescence In Situ Hybridization, uses fluorescent probes to detect specific genetic abnormalities. It adds an extra layer of analysis to traditional karyotyping and can identify issues that might be missed with karyotyping alone.

Understanding the genetic factors that may have contributed to a miscarriage or fetal abnormalities is critical for emotional closure and future family planning. Karyotyping with reflex FISH using products of conception provides valuable information on the chromosomal makeup of the fetal tissue and helps in determining whether genetic abnormalities were a contributing factor. The insights gained from this test are vital for counseling and planning for subsequent pregnancies.

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