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Kappa Light Chain Quantitative, 24 Hours Urine

The Kappa Light Chain Quantitative test is a lab test performed on a 24-hour urine sample to measure the amount of kappa light chains - a component of immunoglobulins, also known as antibodies. These antibodies are produced by plasma cells, a type of white blood cell, to help the body fight against infections. The test can be used to diagnose and monitor certain conditions such as multiple myeloma, a type of blood cancer, and other disorders related to the immune system.


  • Test NameKappa Light Chain Quantitative, 24 Hours Urine
  • Sample TypeUrine
  • Preparations RequiredPatients should avoid heavy physical exercise prior to and during the urine collection period. The first morning urine sample should be discarded, and collection should start from the next urine sample. All subsequent urine passed in the next 24 hours should be collected in the container provided.
  • Report Time5 days

Under normal circumstances, your body maintains a balanced production of two types of light chains: kappa and lambda. When the balance is disturbed due to the overproduction of one type, it could be an indicator of an underlying condition. The Kappa Light Chain Quantitative test helps in detecting this imbalance, providing valuable information to the healthcare provider for making a diagnosis.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is important as it helps diagnose conditions associated with the overproduction of light chains, such as multiple myeloma, Waldenstrom's macroglobulinemia, light chain deposition disease, and certain types of lymphoma. It is also used to monitor treatment effectiveness in these conditions.

No, fasting is not required for this test.

There is no special preparation needed for this test. However, heavy physical exercise should be avoided prior to and during the urine collection period.

This test is typically ordered when a healthcare provider suspects a plasma cell disorder based on symptoms such as bone pain, fatigue, unexplained weight loss, or kidney problems. It may also be ordered to monitor the effectiveness of treatment in patients diagnosed with these conditions.

This test measures the amount of kappa light chains in the urine. High levels of kappa light chains may indicate an overproduction of these proteins by plasma cells, which is often associated with certain disorders.

The frequency of the test will depend on the specific medical condition and the individual patient's health status. Your healthcare provider will provide the best guidance based on your health needs.

Normal values can range from 3.3 to 19.4 mg/24 hours, but may vary depending on the lab and the specific method used for the test. It's important to discuss your results with your healthcare provider for an accurate interpretation.

While collecting a 24-hour urine sample, it's essential to ensure that all urine passed in the specified period is collected, and the first morning sample on the day of starting the collection is discarded. Also, the collected urine should be stored in a cool place during the collection period.

Certain factors like kidney dysfunction, dehydration, and high protein intake can affect the test results.

If the test results show abnormal levels of kappa light chains, it would be beneficial to consult a hematologist or an oncologist, as it could be an indication of a blood or bone marrow disorder.

An elevated level of kappa light chains in the urine might suggest the presence of a plasma cell disorder such as multiple myeloma, light chain deposition disease, or certain types of lymphoma. However, increased levels can also be seen in conditions such as kidney disease. Therefore, it's important to discuss your results with your healthcare provider who can interpret them in the context of your symptoms and other test results.

The Kappa Light Chain Quantitative test involves collecting urine samples, so there's minimal risk involved. You may experience slight discomfort or embarrassment, but no physical harm.

Certain medications may affect the test results. It's crucial to inform your healthcare provider about all the medications, supplements, and vitamins you are currently taking, as they might interfere with your test results.

Lower levels of kappa light chains can occur naturally due to individual differences. However, if the levels are significantly low, it could be due to conditions such as non-Hodgkin's lymphoma, leukemia, or certain kidney diseases. It's crucial to discuss your results with your healthcare provider for a proper interpretation.

No, this test requires a specific protocol and specialized equipment to accurately measure the amount of kappa light chains in the urine. Therefore, it should be performed in a certified laboratory.

Understanding the results of your Kappa Light Chain Quantitative test can provide you and your healthcare provider with valuable information about your health. Abnormal levels could be a sign of a serious condition requiring medical intervention, but they can also be influenced by other factors like medications or kidney function. Always discuss your results with your healthcare provider to understand what they mean in your specific case.

Remember, regular health checks and screenings are key to catching potential health issues early. By understanding the information your tests provide, you can take an active role in your health care. Stay informed, stay proactive, and stay healthy.

Kappa Light Chain Quantitative, 24 Hours Urine
₹ 3700
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet