Inv 16 Gene Rearrangement Qualitative PCR Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation or fasting is required for this test.

₹ 6000


The inv(16)(p13q22) Gene Rearrangement Qualitative PCR test is a specialized genetic test used primarily to diagnose a subtype of acute myeloid leukemia (AML) known as AML with inv(16)(p13q22) or t(16;16)(p13;q22). This specific change involves a rearrangement of genetic material between chromosomes 16 and 22.

Test Name Inv 16 (p13q22) Gene Rearrangement Qualitative PCR
Sample Type Bone Marrow or Blood
Preparations Required No specific preparation or fasting is required for this test.
Report Time 7 Days
Price in Hyderabad ₹ 6000

Why is the inv(16)(p13q22) Gene Rearrangement test important?

The inv(16)(p13q22) test is crucial in the diagnosis and prognosis of certain forms of AML. Patients with this genetic change often respond better to certain treatments and have a more favorable prognosis.

Is fasting required for the inv(16)(p13q22) Gene Rearrangement test?

No, fasting is not required for this test.

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Is there any specific preparation required for this test?

There is no specific preparation required for this test.

When should this test be done?

This test is often done when a person has symptoms suggestive of AML, such as fatigue, frequent infections, and easy bruising or bleeding, and the doctor wants to confirm the diagnosis and subtype of AML.

What information does the inv(16)(p13q22) Gene Rearrangement test provide?

This test detects the specific chromosomal rearrangement associated with a subtype of AML. This information can guide treatment decisions and provide information about prognosis.

How often should this test be performed?

The frequency of this test will depend on your doctor's recommendations, based on your health condition and treatment response.

What are the normal values for the inv(16)(p13q22) Gene Rearrangement test?

In a normal test result, the specific rearrangement of genetic material between chromosomes 16 and 22 is not present.

Are there any precautions to be taken for the inv(16)(p13q22) Gene Rearrangement test?

No special precautions are needed for this test.

What factors can affect the results of the inv(16)(p13q22) Gene Rearrangement test?

The quality of the sample can affect the test results. Therefore, it's important that the test is performed by an experienced technician.

What are the modifiable and non-modifiable factors affecting the results of the inv(16)(p13q22) Gene Rearrangement test?

Non-modifiable factors include the inherent characteristics of the leukemia cells, while modifiable factors can include sample quality and laboratory techniques.

Which doctor should be consulted in case of an abnormal inv(16)(p13q22) Gene Rearrangement test result?

In case of an abnormal result, you should consult a hematologist or oncologist.

What does an abnormal result mean?

An abnormal result indicates the presence of the specific chromosomal rearrangement, which is associated with a subtype of AML.

Can the inv(16)(p13q22) Gene Rearrangement test results be normalized?

Once the rearrangement is present, it will always be detectable in the leukemia cells. However, effective treatment can reduce the number of these abnormal cells, often to undetectable levels.

How reliable is the inv(16)(p13q22) Gene Rearrangement test?

This test is highly specific and sensitive for the detection of this specific chromosomal rearrangement.

What treatment options are available for conditions detected by this test?

Treatment options for AML with inv(16)(p13q22) often include chemotherapy and stem cell transplantation. The specific treatment plan will depend on the patient's overall health and other factors. Always remember, this test is just one aspect of the diagnosis and prognosis. It should be used in conjunction with other clinical findings and laboratory tests, and always consult your doctor for a comprehensive treatment approach.

What happens during the inv(16)(p13q22) Gene Rearrangement test?

During the test, a healthcare professional will take a sample of your bone marrow or blood. This is then sent to a laboratory, where a method called Polymerase Chain Reaction (PCR) is used to identify the specific gene rearrangement.

Is the inv(16)(p13q22) Gene Rearrangement test painful?

The test involves a blood draw or bone marrow extraction. While a blood draw is typically quick and causes minimal discomfort, a bone marrow biopsy can be more uncomfortable. However, local anesthesia is generally used to minimize any pain.

Can I continue my regular medications before the inv(16)(p13q22) Gene Rearrangement test?

Yes, but always inform your doctor about all medications you are taking, as some could potentially interfere with the test results.

How is the inv(16)(p13q22) Gene Rearrangement test different from other genetic tests?

This test specifically looks for a unique gene rearrangement associated with a subtype of AML. It is a specialized test used in the diagnosis and management of this specific type of leukemia.

Can changes in lifestyle affect the outcome of my treatment for AML with inv(16)(p13q22)?

While lifestyle changes cannot directly affect the genetic features of the leukemia cells, a healthy lifestyle can support overall health, improve tolerance to treatment, and enhance recovery.

What symptoms might prompt an inv(16)(p13q22) Gene Rearrangement test?

Symptoms that might prompt the test include persistent fatigue, frequent infections, unexplained weight loss, easy bruising or bleeding, and pain in the bones or joints.

Can other conditions affect the results of the inv(16)(p13q22) Gene Rearrangement test?

Other forms of leukemia or myeloproliferative disorders could potentially interfere with the test. Therefore, this test is interpreted in the context of other laboratory and clinical findings.

Is the inv(16)(p13q22) Gene Rearrangement a hereditary condition?

While the exact causes of AML are not fully understood, it is generally not considered a hereditary condition. The inv(16)(p13q22) rearrangement is typically acquired during a person's lifetime, not inherited from parents.

Can I do anything to lower my risk of developing AML with inv(16)(p13q22)?

While you can't control certain risk factors for AML, like age and certain genetic disorders, you can control other risk factors such as exposure to certain chemicals and radiation, smoking, and maintaining a healthy lifestyle.

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