Immunohistochemistry - Cytokeratin 7 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific patient preparation is required for this test as the sample is usually obtained during a biopsy or surgical procedure.

₹ 2000


Cytokeratin 7 (CK7) is a protein found in certain epithelial cells, including those of the lungs and breast. It is part of the intermediate filament family of proteins which help to maintain cell structure and shape.

The Immunohistochemistry - Cytokeratin 7 (IHC - CK7) test uses antibodies specific to CK7 to identify the presence of this protein in tissue samples. This test is crucial in the diagnosis and differentiation of various types of tumors, particularly in identifying cancers of the lung, breast, and gynecological system.

Test Name IHC - Cytokeratin 7 - CK7
Sample Type Tissue
Preparations Required No specific patient preparation is required for this test as the sample is usually obtained during a biopsy or surgical procedure.
Report Time 3 days
Price in Hyderabad ₹ 2000

What is the process involved in an IHC - CK7 test?

The IHC - CK7 test involves treating the tissue sample with primary antibodies that are specific to CK7. If CK7 is present, these antibodies will bind to it. Following this, a secondary antibody, linked to an enzyme that can induce color change, is added. The presence of CK7 is thus indicated by a color change in the tissue sample.

What does a positive result mean?

A positive IHC - CK7 test indicates the presence of CK7 proteins in the cells of the examined tissue. This is often associated with cancers of the lung, breast, and gynecological system. However, a complete diagnosis will consider this result along with other clinical findings and test results.

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Does the IHC - CK7 test cause any pain?

The IHC - CK7 test itself does not cause any pain. However, the process of obtaining a tissue sample for the test, such as through a biopsy or surgical procedure, may cause discomfort or pain.

How reliable is the IHC - CK7 test?

The reliability of the IHC - CK7 test depends on the quality of the tissue sample and the expertise of the laboratory conducting the test. It is considered a reliable tool for identifying and differentiating certain types of cancers.

What does a negative IHC - CK7 test imply?

A negative result means the examined cells do not contain CK7 proteins. While this can rule out certain types of cancers, it does not necessarily mean the tissue is benign. Other tests may be required to arrive at a complete diagnosis.

Why is the IHC - CK7 test used in cancer diagnosis?

IHC - CK7 test is a significant tool for diagnosing cancer because it identifies the presence of CK7 proteins which are often present in certain types of cancers. The unique pattern of CK7 expression can provide critical insights into the origin of the tumor and help distinguish between different types of cancers.

Are there any risks associated with this test?

The IHC - CK7 test itself does not pose any risks. However, obtaining the tissue sample for the test, such as through a biopsy or surgical procedure, may carry potential risks including infection, bleeding, or adverse reactions to anesthesia.

How are the results of the IHC - CK7 test interpreted?

Results of the IHC - CK7 test are interpreted by pathologists who examine the stained tissue sample under a microscope. If the cells in the tissue sample show a color change, it is indicative of the presence of CK7 proteins.

Are there any factors that can affect the results of the IHC - CK7 test?

Factors that can affect the results of the IHC - CK7 test include poor sample quality, improper handling of the tissue sample, and technical issues with the staining process.

What should I do if my test results are abnormal?

If your test results are abnormal, it's important to discuss the results with your healthcare provider. They will interpret your results in the context of your overall health and clinical history. Further diagnostic tests may be necessary to confirm a diagnosis.

Is CK7 always present in cancerous tissues?

CK7 is not always present in all types of cancerous tissues. It is typically found in certain cancers like lung, breast, and gynecological cancers. Therefore, the absence of CK7 does not rule out all forms of cancer.

Can the IHC - CK7 test differentiate between benign and malignant tumors?

The IHC - CK7 test is not specifically designed to distinguish between benign and malignant tumors. However, its results can contribute to this differentiation as part of a wider diagnostic process, including other tests and examinations.

Is this test done on an outpatient basis?

Yes, the procedure to obtain the tissue sample can typically be performed on an outpatient basis. However, depending on the location of the sample and the patient's overall health, a short hospital stay may be required.

Is the IHC - CK7 test covered by insurance?

Coverage for the IHC - CK7 test can vary widely, so it's important to check with your insurance provider. Most insurance providers do cover this test when it is deemed medically necessary.

Who performs the IHC - CK7 test?

The IHC - CK7 test is performed in a laboratory by a pathologist or a medical laboratory scientist. The procedure to collect the tissue sample is done by a healthcare provider.

The Immunohistochemistry - Cytokeratin 7 (IHC - CK7) test is a highly specific diagnostic tool that plays a vital role in diagnosing and understanding the nature of various cancers. It's crucial to remember that while the test provides valuable information, it is just a piece of the puzzle in the larger diagnostic process. All test results should be discussed with and interpreted by a qualified healthcare provider who can provide a comprehensive understanding of the patient's health status.

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