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Lab Test

Immunofixation- Quantitative Serum

The Immunofixation-Quantitative Serum test is a comprehensive diagnostic tool, comprising of various components, including Protein Electrophoresis, Immunofixation, measurement of IgG, IgM, IgA levels, Free Light Chains - Kappa & Lambda, and Beta 2 Microglobulin. This test aims to identify and quantify various proteins present in the blood to detect and monitor diseases, particularly plasma cell disorders like multiple myeloma and other conditions affecting the immune system.


  • Test NameImmunofixation- Quantitative Serum
  • Sample TypeBlood
  • Preparations RequiredNo special preparation is needed for this test. However, make sure to inform your healthcare provider about any medications or supplements you're currently taking.
  • Report TimeNext day

Protein Electrophoresis is a method used to separate proteins based on their size and charge. Immunofixation further characterizes these proteins. IgG, IgM, and IgA are different classes of immunoglobulins (antibodies) that play a crucial role in our body's immune response. An abnormal level of these proteins may indicate an immune system disorder.

The Free Light Chains - Kappa and Lambda, are parts of antibodies, and their presence in high amounts may signify an overproduction due to conditions such as multiple myeloma. Beta 2 Microglobulin is a protein found on the surface of many cells and can be a marker for certain types of cancer, including multiple myeloma and lymphoma, as well as kidney disease.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

This test is typically conducted when a healthcare provider suspects a plasma cell disorder, such as multiple myeloma, or other immune system disorders. It aids in the diagnosis and monitoring of these conditions, providing vital insights into the presence and levels of various proteins in the blood.

No, fasting is not required for this test.

This test measures the presence and levels of different proteins in the blood, including IgG, IgM, IgA, free light chains (kappa and lambda), and beta 2 microglobulin. The results can help assess immune system function and detect conditions like plasma cell disorders and kidney disease.

The frequency of this test depends on the specific medical condition, its severity, and the individual's response to any ongoing treatment. Your healthcare provider will guide you on when you should have this test.

The normal ranges for these protein levels vary depending on the laboratory performing the test. In general, normal ranges might be:

  • 700-1600 mg/dL
  • 40-230 mg/dL
  • 70-400 mg/dL
  • Free Kappa Light Chains: 3.3-19.4 mg/L
  • Free Lambda Light Chains: 5.7-26.3 mg/L
  • Beta 2 Microglobulin: 0.7-1.8 mg/L

Remember, only a healthcare professional can interpret these results based on your overall health and specific circumstances.

There are no special precautions required for this test. It's always a good idea to inform your healthcare provider about all medications, over-the-counter drugs, and dietary supplements you are taking, as certain substances can interfere with the test results.

Several factors can affect the results, including kidney disease, liver disease, malnutrition, certain medications, and the presence of other medical conditions. Always share your full medical history and current health status with your healthcare provider for the most accurate interpretation of your test results.

If your test results are abnormal, you should consult with your healthcare provider. Depending on the specific abnormality, you may also need to see a hematologist (a specialist in blood disorders) or an immunologist (a specialist in immune system disorders).

High levels of these proteins can be a sign of various conditions, including multiple myeloma, lymphoma, kidney disease, or an autoimmune disorder. If these levels are high, your healthcare provider will likely recommend further tests to confirm the diagnosis and determine the most appropriate treatment plan.

Yes, in addition to multiple myeloma, conditions such as chronic infections, autoimmune diseases, and kidney disease can cause changes in the levels of these proteins. Certain medications can also affect protein levels.

Yes, certain medications may interfere with the test results. Always inform your healthcare provider about all the medications, over-the-counter drugs, and dietary supplements you are taking.

If abnormal proteins are detected in the blood, it may indicate an underlying medical condition, such as a plasma cell disorder or an immune system disease. Your healthcare provider will guide you on the next steps, which could include further tests or treatment.

Yes, apart from plasma cell disorders, this test can also help diagnose and monitor conditions like kidney disease, certain autoimmune disorders, and lymphoma.

Yes, this test can be beneficial for both men and women, especially if they show symptoms suggesting a plasma cell or immune system disorder.

While lifestyle changes do not directly impact the levels of these proteins, maintaining a healthy lifestyle can positively influence overall health, potentially reducing the risk of diseases that could affect these protein levels.

The frequency of this test will depend on the type and stage of the plasma cell disorder, the treatment approach, and how well the disease is responding to treatment. Your healthcare provider will guide you based on your specific condition.

Abnormal results should be discussed with your healthcare provider. They will interpret the results in light of your overall health, symptoms, and medical history, and will guide you on the appropriate next steps.

There are minimal risks associated with this test. It involves a blood draw, which can cause mild pain, bruising, or infection at the site of the needle stick, but these complications are rare.

The Immunofixation-Quantitative Serum test provides valuable insights into the functioning of the immune system and aids in the diagnosis and monitoring of plasma cell disorders and other conditions. Always consult with your healthcare provider for any concerns or questions about this test. They can provide the best advice based on your individual health status.

IMMUNOFIXATION ELECTROPHORESIS (IFE), SERUM QUANTITATIVE
₹ 9900
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