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Immunofixation Electrophoresis (IFE), Qualitative - 24H Urine

Immunofixation Electrophoresis (IFE), Qualitative - 24H Urine

Immunofixation Electrophoresis (IFE), Qualitative - 24H Urine is a diagnostic test that's primarily used to detect and identify abnormal proteins or monoclonal proteins (M-proteins) in the urine. This test is particularly useful in the diagnosis and monitoring of certain conditions, notably multiple myeloma and other plasma cell disorders.

During the IFE process, proteins in the urine sample are first separated by electrophoresis and then treated with antisera (antibodies) that bind to specific types of proteins, such as immunoglobulins and light chains. This forms antigen-antibody complexes, which can then be visualized and identified, helping to determine the type and quantity of any abnormal proteins present.


  • Test NameImmunofixation Electrophoresis (IFE), Qualitative - 24H Urine
  • Sample TypeUrine
  • Preparations RequiredNo specific dietary restrictions or fasting is required. It's recommended to avoid rigorous physical activities 24 hours before the test as it may interfere with the results. Always inform your healthcare provider about all the medications and supplements you are currently taking.
  • Report Time4 days

Why is the 24-hour urine IFE test important?

The 24-hour urine IFE test is important in the diagnosis and monitoring of plasma cell disorders like multiple myeloma. This test can detect and identify M-proteins in the urine, which can help in establishing a diagnosis, determining the extent of the disease, and monitoring response to treatment.

Is fasting required for this test?

No, fasting is not required for the 24-hour urine IFE test.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is typically done when symptoms suggest a plasma cell disorder, such as multiple myeloma, or when a routine blood or urine test shows the presence of abnormal proteins. It may also be ordered periodically to monitor the disease progress or response to treatment in diagnosed cases.

The 24-hour urine IFE test measures and identifies the specific types of M-proteins present in the urine. The presence of M-proteins can indicate a plasma cell disorder like multiple myeloma.

The frequency of this test will depend on your specific condition and the judgment of your healthcare provider. For patients under treatment for a plasma cell disorder, this test may be repeated periodically to monitor response to treatment.

In a healthy individual, M-proteins are usually not detected in the urine. If detected, it may indicate a plasma cell disorder or other conditions. The interpretation of results should be done by a healthcare provider considering the overall clinical scenario.

No special precautions are necessary for this test, but it's advised to avoid rigorous physical activities 24 hours before the test. Additionally, inform your healthcare provider about all the medications and supplements you are currently taking.

Certain factors can affect the test results, including dehydration, kidney disease, and the intake of certain medications. Also, improper collection of the 24-hour urine sample can result in inaccurate results.

If your test results are abnormal, indicating the presence of M-proteins in urine, consult with your healthcare provider. They will interpret the results considering your overall health, symptoms, and medical history, and suggest appropriate next steps, which may include further testing and treatment if necessary.

There are no significant risks associated with providing a urine sample for this test. However, it's crucial to collect the sample correctly to avoid inaccurate results.

Yes, certain medications may affect the test results. Always inform your healthcare provider about all the medications, over-the-counter drugs, and dietary supplements you are taking.

While multiple myeloma is a common reason for conducting the test, it can also be used to diagnose or monitor other plasma cell disorders and certain kidney conditions.

If M-proteins are detected in the urine, it can indicate a plasma cell disorder or another condition. Your healthcare provider may order further tests to confirm a diagnosis and determine the best course of treatment.

The test is typically performed in a clinical laboratory under the supervision of a trained lab technician.

Yes, both men and women can undergo this test if suggested by their healthcare provider, as plasma cell disorders like multiple myeloma affect both genders.

Lifestyle changes do not directly influence the results of the 24-hour urine IFE test. However, maintaining a healthy lifestyle can positively impact overall health and the body's ability to manage or recover from diseases.

No, the test is not painful. It involves collecting your urine over a 24-hour period.

The 24-hour urine IFE test is a reliable tool for detecting and identifying M-proteins in urine. However, it's essential to collect the urine sample correctly over a 24-hour period to ensure accurate results.

After the test is done, your healthcare provider will review the results and discuss them with you. If the test results indicate the presence of M-proteins, further tests may be required to confirm a diagnosis and determine the best course of treatment.

Yes, in addition to plasma cell disorders, this test can also help in the diagnosis and management of certain kidney conditions.

Understanding the 24-hour urine Immunofixation Electrophoresis (IFE) can be an essential part of your healthcare journey. This test can provide valuable insights for your healthcare provider, particularly in diagnosing and managing plasma cell disorders. As always, it's important to discuss any concerns or questions about this test with your healthcare provider. They can provide guidance on what these results mean for your health and the next steps in your care.

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