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IHC-TLE 1

IHC-TLE 1

The IHC-TLE 1 (Transducin-Like Enhancer of Split 1) Diagnostic Test is a vital tool primarily used in the field of oncology. This test focuses on identifying the presence or absence of the TLE 1 protein in a tissue sample, using a technique known as immunohistochemistry (IHC).

TLE 1 is a protein that in humans is encoded by the TLE1 gene. Abnormal expression of this protein is often associated with certain types of cancers, particularly synovial sarcoma. This test, therefore, serves a critical role in diagnosing such cancers and assisting clinicians in determining the most appropriate treatment plan.


  • Test NameIHC-TLE 1
  • Sample TypeTissue
  • Preparations RequiredNo special preparation is required for this test. Patients should maintain their normal routines and take any prescribed medications unless otherwise instructed by their healthcare provider.
  • Report Time3 days

Why is the IHC-TLE 1 Diagnostic Test important?

The IHC-TLE 1 test is instrumental in diagnosing and distinguishing certain types of cancers, particularly synovial sarcoma. By identifying the presence or absence of the TLE 1 protein, it assists in confirming the diagnosis and aids in deciding the most suitable treatment strategy.

Is fasting necessary for this test?

No, fasting is not required for the IHC-TLE 1 test. The test is performed on a tissue sample, so there are no dietary restrictions or preparations necessary.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is typically recommended when there's a suspicion of synovial sarcoma, a rare form of cancer that usually occurs near the joints in the arms, legs, or trunk. It can help confirm the diagnosis and guide treatment.

The IHC-TLE 1 test detects the presence or absence of the TLE 1 protein in tissue samples. Overexpression of TLE 1 can provide significant clues about the presence of certain types of tumors, primarily synovial sarcoma.

The frequency of this test depends on an individual's specific circumstances, including their medical history and current health status. It's typically performed when there's a clinical suspicion of certain types of cancers. Your healthcare provider will guide you based on your unique needs.

The "normal" value for the IHC-TLE 1 test can vary depending on the specific lab performing the test and the context. Typically, TLE 1 should not be overexpressed in healthy tissue samples. Any deviation from expected results should be evaluated by a healthcare provider in the context of your overall health and clinical scenario.

No special precautions are necessary for this test. It is suggested to continue with your normal routine and diet unless your healthcare provider instructs otherwise.

The levels of TLE 1 can be influenced by the presence or absence of specific types of tumors, particularly synovial sarcoma. Other medical conditions and certain treatments may also impact these levels.

If your test results are abnormal, it's crucial to consult with a healthcare provider, preferably an oncologist. They can interpret the results in the context of your overall health and guide further investigations or treatment as necessary.

The risks associated with the IHC-TLE 1 test mainly relate to the biopsy procedure to obtain the tissue sample. These risks can include discomfort, bleeding, or infection at the biopsy site.

Certain medications may impact the expression of TLE 1, but this influence is usually not significant enough to interfere with the interpretation of results in a cancer diagnostic context.

While the primary use of the IHC-TLE 1 test is in diagnosing and classifying certain cancers, particularly synovial sarcoma, it can also be used in other specific clinical scenarios or for research purposes as determined by a healthcare provider.

A positive result for TLE 1 indicates an overexpression of this protein in the tissue sample. This can provide significant information about the presence of certain types of tumors, facilitating their classification and helping to determine the most appropriate treatment approach.

Yes, the IHC-TLE 1 test is often part of a broader panel of tests, including other immunohistochemical markers, cytogenetic tests, and other laboratory tests to diagnose and classify tumors accurately.

This test is typically performed in a specialized laboratory under the supervision of a pathologist.

Yes, the IHC-TLE 1 test can be performed on tissue samples from both men and women, as synovial sarcoma, the primary condition that this test aids in diagnosing, affects both genders.

While the primary application of the IHC-TLE 1 test is in diagnosing synovial sarcoma, it may also be used in other specific clinical situations or for research purposes as determined by a healthcare provider.

Lifestyle changes do not directly influence the levels of TLE 1 protein. These levels are primarily determined by the presence of specific tumors, such as synovial sarcoma.

The test itself is not painful. However, obtaining the tissue sample for the test can cause some discomfort as it involves a biopsy procedure.

The IHC-TLE 1 test can provide crucial information for the diagnosis and classification of certain tumors, like synovial sarcoma, which can guide the choice of therapy. However, individual responses to treatment can vary, and additional tests may be needed to monitor your progress.

Understanding the significance of the IHC-TLE 1 Diagnostic Test can be essential in managing your healthcare journey, particularly if you are dealing with conditions like synovial sarcoma. This test provides vital information to your healthcare provider, enabling them to make an accurate diagnosis and determine the most effective treatment plan. Always remember that while this test provides critical information, your healthcare provider's guidance is crucial in interpreting the results and deciding the next steps in your healthcare journey.

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