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IHC - Thyroglobulin

IHC - Thyroglobulin

The IHC - Thyroglobulin Diagnostic Test plays a critical role in the field of endocrinology, particularly in the diagnosis and management of thyroid diseases. Thyroglobulin (Tg) is a protein produced by the cells of the thyroid gland, the butterfly-shaped gland located at the base of the neck. This protein serves as the precursor for thyroid hormones that control the body's metabolism.


  • Test Name IHC - Thyroglobulin (IHC)
  • Sample Type Tissue
  • Preparations Required No special preparation is needed for this test. Patients should continue with their regular diet and medication regimen as directed by their healthcare provider.
  • Report Time 3 days

The IHC - Thyroglobulin test uses a method known as immunohistochemistry (IHC) to detect the presence of thyroglobulin in tissue samples. This test is instrumental in diagnosing thyroid diseases and managing patients with thyroid cancer, as thyroglobulin can serve as a tumor marker.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The IHC - Thyroglobulin test is significant as it aids in diagnosing thyroid conditions, and is crucial in the follow-up of patients who have been treated for differentiated thyroid cancer.

No, fasting is not required for this test as it involves a tissue sample, not blood.

This test is usually recommended if a patient has symptoms suggestive of a thyroid disease, has been diagnosed with thyroid cancer, or is undergoing follow-up after thyroid cancer treatment.

The test detects the presence of thyroglobulin in tissue samples. Increased levels can suggest the presence or recurrence of differentiated thyroid cancer.

For patients who have been treated for differentiated thyroid cancer, regular monitoring with this test is often recommended, usually every 6 to 12 months. The frequency depends on the individual's specific circumstances and should be guided by their healthcare provider.

This test is performed on tissue, so there's no absolute 'normal' value. Results will vary and should be interpreted by your healthcare provider in conjunction with other diagnostic findings.

There are no specific precautions needed before this test. Continue with your regular diet and medications unless otherwise instructed by your healthcare provider.

Thyroglobulin levels can be influenced by the presence of thyroid disease, thyroid cancer, or the presence of thyroid tissue following treatment for thyroid cancer.

If your results are abnormal, it is important to discuss them with an endocrinologist or the healthcare provider who ordered the test. They can interpret the results in the context of your overall clinical picture and guide further investigations or treatment as needed.

The risks associated with this test are mostly related to the biopsy procedure used to obtain the tissue sample, which can cause discomfort, bleeding, or infection.

Yes, certain medications, such as levothyroxine and antithyroid drugs, can influence thyroglobulin levels.

While the test can detect thyroglobulin in tissue samples, it is typically not used as a first-line screening tool for thyroid diseases. However, it plays a vital role in the management of differentiated thyroid cancer.

A positive test result means that thyroglobulin is present in the tissue sample. This can be an indication of differentiated thyroid cancer, particularly in patients who have had their thyroid gland removed.

Yes, the IHC - Thyroglobulin test is often performed in conjunction with other tests such as ultrasound imaging, radioactive iodine scans, and thyroglobulin blood tests.

This test is performed by a pathologist in a laboratory setting.

Yes, this test can be performed on both men and women if they have symptoms suggestive of a thyroid condition or have been treated for thyroid cancer.

While the primary use of the IHC - Thyroglobulin test is for the detection and monitoring of thyroid diseases and differentiated thyroid cancer, it may be utilized in other circumstances as guided by a healthcare provider.

Lifestyle changes do not directly affect thyroglobulin levels, which are primarily influenced by the state of the thyroid gland or the presence of differentiated thyroid cancer.

The test itself is not painful. However, the biopsy procedure used to collect the tissue sample may cause some discomfort.

The IHC - Thyroglobulin test can provide valuable information about the presence or recurrence of differentiated thyroid cancer, which can influence treatment decisions and prognosis. However, individual response to treatment involves many factors and should be discussed with your healthcare provider.

In summary, the IHC - Thyroglobulin Diagnostic Test is an essential tool in managing thyroid conditions, particularly differentiated thyroid cancer. Always consult your healthcare provider to understand your test results better and chart the best course of action for your health journey.

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