IHC-TFE3 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific patient preparation is needed for this test. However, ensure you inform your healthcare provider of your current medications or health conditions.

₹ 2500


The IHC-TFE3 diagnostic test plays a significant role in detecting and evaluating rare forms of tumors, particularly renal cell carcinoma (RCC) and alveolar soft part sarcoma (ASPS). The test targets Transcription Factor E3 (TFE3), a protein that when abnormally expressed, can contribute to the development of these tumors.

TFE3 plays a role in cell growth and proliferation. In certain cases, a gene fusion involving the TFE3 gene can lead to overproduction of the TFE3 protein, driving the growth of tumor cells. The IHC-TFE3 test is designed to identify this overexpression, assisting in the diagnosis of these particular types of cancers.

Test Name IHC-TFE3
Sample Type Tissue
Preparations Required No specific patient preparation is needed for this test. However, ensure you inform your healthcare provider of your current medications or health conditions.
Report Time 3 days
Price in Hyderabad ₹ 2500

Why is the IHC-TFE3 test important?

The IHC-TFE3 test is crucial for diagnosing specific rare forms of cancer, particularly those associated with abnormal TFE3 expression. It aids in distinguishing these unique tumors from more common types, which is vital for determining the most effective treatment strategy.

Is fasting required for the IHC-TFE3 test?

No, fasting is not required for this test. However, it's essential to inform your healthcare provider about any medications or supplements you're taking, as they might affect the test results.

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When should I get the IHC-TFE3 test?

The test is generally performed when a patient presents with clinical signs and symptoms suggestive of RCC or ASPS, or if a tumor has features suspicious for a TFE3 gene fusion. Your healthcare provider will guide you based on your specific clinical scenario.

What information does the IHC-TFE3 test provide?

The test identifies the overexpression of the TFE3 protein in tissue samples, indicating a potential TFE3 gene fusion. This information can help diagnose certain types of rare tumors, guiding appropriate treatment.

How often should I get tested?

The frequency of this test depends on the clinical situation and your healthcare provider's recommendation. It is not typically a routinely performed test but is used when specific rare tumors are suspected.

What are the normal values for the IHC-TFE3 test?

This test typically provides qualitative results, indicating the presence or absence of TFE3 overexpression. Normal results may depend on the specific laboratory performing the test. Your healthcare provider will help you understand your results in the context of your overall health and symptoms.

Are there precautions to take before or after the IHC-TFE3 test?

No special precautions are needed for this test. As with any medical procedure, follow the instructions provided by your healthcare provider.

What factors can affect the levels of TFE3?

Factors affecting TFE3 levels are typically non-modifiable, such as genetic alterations leading to a TFE3 gene fusion. There are no known modifiable factors affecting TFE3 levels.

Which doctor should I consult if my IHC-TFE3 test result is abnormal?

An abnormal test result would typically be discussed with a specialist such as an oncologist or pathologist. They can provide expert interpretation of the test result in the context of your overall health and other diagnostic findings.

Can I take medications before the IHC-TFE3 test?

You should inform your healthcare provider about any medications or supplements you're taking. While these are unlikely to affect the test, your healthcare provider needs to have all relevant information to interpret your results accurately.

Is the IHC-TFE3 test painful?

The test itself is not painful. However, the procedure to obtain the tissue sample, such as a biopsy, may cause some discomfort. Your healthcare provider will use local anesthesia to minimize discomfort.

What should I do after the test?

After the test, follow your healthcare provider's instructions for wound care and next steps. If you experience any unusual symptoms or side effects, seek medical attention immediately.

How accurate is the IHC-TFE3 test?

The IHC-TFE3 test is considered accurate for identifying the overexpression of the TFE3 protein in tissue samples. However, the test results should be interpreted alongside other clinical information and diagnostic findings.

How long does it take to get the results of an IHC-TFE3 test?

The turnaround time for the IHC-TFE3 test typically ranges from 7 to 10 days, but it can vary depending on the specific laboratory and test conditions.

Can the IHC-TFE3 test be performed on children?

Yes, this test can be performed on patients of all ages if clinically necessary. If you have concerns about your child undergoing this test, it's best to discuss them with your healthcare provider.

Overall, the IHC-TFE3 diagnostic test is a powerful tool in the detection and management of certain rare tumors. By identifying the overexpression of TFE3, this test provides valuable insights that can guide targeted treatment strategies, offering hope to patients diagnosed with these unique forms of cancer. Remember, knowledge is power, especially when navigating the complexities of cancer care.

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