IHC-Synaptophysin Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific preparation is required for this test.

₹ 2000


The IHC-Synaptophysin test is a diagnostic test that uses immunohistochemistry to detect the presence of the synaptophysin protein in tissue samples. Synaptophysin is an integral membrane glycoprotein found in pre-synaptic vesicles in neurons, and its presence is generally indicative of neuroendocrine cells. Therefore, the test is often used in the diagnosis of neuroendocrine tumors and some forms of neuroblastoma.

Test Name IHC-Synaptophysin
Sample Type Tissue
Preparations Required No specific preparation is required for this test.
Report Time 3 days
Price in Hyderabad ₹ 2000

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What is the IHC-Synaptophysin test?

The IHC-Synaptophysin test is a diagnostic procedure that uses specific antibodies to detect synaptophysin protein in tissue samples. Elevated levels of synaptophysin are commonly seen in neuroendocrine tumors and some neuroblastomas.

How is the IHC-Synaptophysin test performed?

The IHC-Synaptophysin test is performed on a tissue biopsy sample. This sample is treated with antibodies that bind to the synaptophysin protein, allowing for identification under a microscope.

Do I need to fast before the IHC-Synaptophysin test?

No, fasting is not required before this test.

Are there any specific preparations required for the IHC-Synaptophysin test?

No special preparations are necessary for this test.

When should I consider taking the IHC-Synaptophysin test?

Your healthcare provider might recommend this test if they suspect a neuroendocrine tumor or certain types of neuroblastoma. This test can provide essential information for diagnosing these conditions.

What do the results of the IHC-Synaptophysin test mean?

A positive result indicates that synaptophysin was detected in the tissue sample, suggesting the possibility of a neuroendocrine tumor or neuroblastoma. A negative result suggests that synaptophysin was not detected in the tissue sample.

How often should I get this test done?

The frequency of this test depends on your health situation and the discretion of your healthcare provider.

What precautions should I take before and after the IHC-Synaptophysin test?

No specific precautions are required for this test. However, it's important to discuss the results with your healthcare provider to understand what they mean for your health status.

What factors could affect the results of the IHC-Synaptophysin test?

The results could be affected by technical issues or errors during the biopsy or testing procedure, but such instances are relatively rare.

If my IHC-Synaptophysin test result is positive, who should I consult?

A positive test result should be discussed with your healthcare provider who ordered the test. Based on the findings, they may refer you to a specialist, such as an oncologist, for further evaluation and treatment planning.

Is the IHC-Synaptophysin test used for both diagnosis and monitoring of diseases?

Yes, the IHC-Synaptophysin test can be used both for diagnosing diseases like neuroendocrine tumors and for monitoring the progression of the disease or the effectiveness of treatment.

Can the IHC-Synaptophysin test be performed on children?

Yes, the IHC-Synaptophysin test can be performed on individuals of all ages, including children. However, the necessity and appropriateness of the test would be determined by a healthcare provider.

Are there any risks associated with the IHC-Synaptophysin test?

The IHC-Synaptophysin test is generally safe, with minimal risks. However, because it involves a biopsy, there might be some risks associated with the biopsy procedure itself, such as bleeding or infection.

Can the IHC-Synaptophysin test give a false positive or negative result?

While uncommon, false positives or negatives can occur due to technical errors during the testing process. Hence, results should always be interpreted in conjunction with other diagnostic information and clinical findings.

Can the IHC-Synaptophysin test be performed during pregnancy?

The appropriateness of the IHC-Synaptophysin test during pregnancy would depend on the individual's health status and the necessity of the test. This decision should be made in consultation with a healthcare provider.

What type of tissue sample is needed for the IHC-Synaptophysin test?

The type of tissue sample required for the IHC-Synaptophysin test will depend on the suspected location of the disease. If a neuroendocrine tumor is suspected, a biopsy from the suspected site may be required.

What does a positive IHC-Synaptophysin result indicate?

A positive IHC-Synaptophysin result indicates the presence of the synaptophysin protein in the tissue sample, which could suggest diseases like neuroendocrine tumors or certain types of neuroblastoma. However, a definitive diagnosis typically requires further diagnostic procedures.

Are there any medications that could interfere with the results of the IHC-Synaptophysin test?

There are no known medications that interfere with the IHC-Synaptophysin test. However, it's always crucial to discuss all medications and supplements you're currently taking with your healthcare provider before any medical test.

How reliable is the IHC-Synaptophysin test in diagnosing diseases?

The IHC-Synaptophysin test is a reliable tool when used alongside other tests and clinical findings. However, a single test should not be used as the sole basis for diagnosis. Your healthcare provider will interpret the test results in conjunction with other diagnostic information.

Can lifestyle factors affect the results of the IHC-Synaptophysin test?

The IHC-Synaptophysin test measures the presence of synaptophysin, a protein produced by certain types of cells. Lifestyle factors do not directly impact the production of this protein. However, maintaining a healthy lifestyle can positively influence your overall health.

What does a negative result mean in an IHC-Synaptophysin test?

A negative result on the IHC-Synaptophysin test indicates that synaptophysin was not detected in the tissue sample. However, a negative result does not necessarily rule out disease, and additional tests may be necessary to confirm a diagnosis.

Comprehending the IHC-Synaptophysin test can help patients undergoing evaluations for neuroendocrine tumors or certain types of neuroblastoma. The test, while a significant tool in the diagnostic process, is just one part of the overall picture. It's essential to communicate openly with your healthcare provider about the results and the next steps in your healthcare journey.

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