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IHC-SOX2

IHC-SOX2

The IHC-SOX2 test uses immunohistochemistry, a method that leverages specific antibodies, to detect the SOX2 protein in tissue samples. This protein is an essential component for maintaining self-renewal or pluripotency of undifferentiated stem cells. Some tumors, such as lung squamous cell carcinoma and small cell lung cancer, often show high levels of SOX2. Thus, this test can aid in diagnosing these conditions and providing crucial insights into the patient's health status.


  • Test NameIHC-SOX2
  • Sample TypeTissue Biopsy
  • Preparations RequiredNo specific preparation is required for this test.
  • Report Time3 days

What is the IHC-SOX2 test?

The IHC-SOX2 test is an immunohistochemistry test that detects the presence of the SOX2 protein in tissue samples. Elevated levels of this protein can suggest the presence of certain types of cancers, including squamous cell carcinoma and small cell lung cancer.

How is the IHC-SOX2 test performed?

The test is performed on a tissue sample, often collected via biopsy. The sample is treated with antibodies designed to bind to the SOX2 protein. If present, the SOX2 protein can be identified under a microscope.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No, fasting is not necessary for this test.

No special preparations are necessary for this test.

Your healthcare provider may order this test if there's a suspicion of a condition like squamous cell carcinoma or small cell lung cancer. It's an essential tool in establishing or confirming a diagnosis.

A positive result indicates that the SOX2 protein was detected in the tissue sample, suggesting the possibility of certain cancers. A negative result means that the SOX2 protein wasn't found in the tissue sample.

The frequency of this test will be determined by your healthcare provider, based on your individual health situation and potential risk factors.

No specific precautions are needed for this test. However, it's important to discuss the results with your healthcare provider to understand what they imply about your health.

Technical errors during the biopsy or testing procedure could potentially affect the results. However, such instances are relatively rare.

A positive test result should be discussed with your healthcare provider who ordered the test. They can provide more information about what this means for your health and suggest appropriate next steps. This may include referral to a specialist, such as an oncologist.

Yes, the IHC-SOX2 test can serve both diagnostic and monitoring purposes. It can help diagnose certain cancers, and it can also track the progress of the disease or the effectiveness of treatment.

Yes, the IHC-SOX2 test can be performed on individuals of all ages, including children. However, the necessity and appropriateness of the test would be determined by a healthcare provider.

The IHC-SOX2 test is generally safe, posing minimal risks. However, because it involves a biopsy, there might be some risks associated with the biopsy procedure itself, like bleeding or infection.

While uncommon, false positive or negative results can occur due to technical issues or errors during the testing procedure. As such, the test results are typically interpreted in the context of other diagnostic information.

The appropriateness of the IHC-SOX2 test during pregnancy would depend on the individual's health status and the necessity of the test. This decision should be made in consultation with a healthcare provider.

The type of tissue sample needed for the IHC-SOX2 test depends on the suspected location of the disease. For example, if lung cancer is suspected, a lung tissue biopsy might be collected.

A positive IHC-SOX2 result indicates the presence of the SOX2 protein in the tissue sample, which can suggest certain diseases, such as squamous cell carcinoma or small cell lung cancer. However, the test alone is not enough for a definitive diagnosis, and further diagnostic procedures may be required.

There are no known medications that interfere with the IHC-SOX2 test. However, it's always important to discuss all medications and supplements you're currently taking with your healthcare provider prior to any medical testing.

The IHC-SOX2 test is a reliable diagnostic tool when used alongside other tests and clinical findings. However, a single test should not be used as the sole basis for a diagnosis. Your healthcare provider will interpret the test results in the context of the overall clinical picture.

The IHC-SOX2 test measures the presence of the SOX2 protein, a factor produced by certain types of cells, irrespective of lifestyle factors. However, a healthy lifestyle can contribute positively to your overall health and well-being.

A negative result on the IHC-SOX2 test indicates that the SOX2 protein was not detected in the tissue sample. However, a negative result does not necessarily rule out disease, and additional tests may be necessary to confirm a diagnosis.

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