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Lab Test

IHC-S100

The IHC-S100 test is a diagnostic tool used in pathology to detect the presence of the S100 protein in tissue samples. This protein is often found in cells derived from the neural crest (Schwann cells, melanocytes, etc.), chondrocytes, adipocytes, myoepithelial cells, macrophages, Langerhans cells, dendritic cells, and keratinocytes. The test is essential in diagnosing conditions such as melanoma and some types of nerve tumors.


  • Test NameIHC-S100
  • Sample TypeTissue
  • Preparations RequiredNo special preparation is required for this test.
  • Report Time3 days

What is the IHC-S100 test?

The IHC-S100 test is a pathology test that uses specific antibodies to detect the presence of the S100 protein in tissue samples. This protein is typically present in certain types of cells, and its detection can aid in diagnosing a variety of conditions.

How is the IHC-S100 test performed?

The test is performed on a tissue sample, typically obtained through a biopsy. The tissue is treated with antibodies specific to the S100 protein. If this protein is present, it will bind with the antibodies and can be detected under a microscope.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No, fasting is not necessary for this test.

No specific preparations are necessary for this test.

The IHC-S100 test is typically ordered by your healthcare provider if there is suspicion of a condition such as melanoma or certain types of nerve tumors.

A positive result indicates the presence of the S100 protein in the tissue sample, which can support the diagnosis of certain conditions. A negative result means that the S100 protein was not detected in the tissue sample.

The frequency of this test will be determined by your healthcare provider based on your individual health status and potential risk factors.

No specific precautions are needed for this test. However, it's important to discuss the results with your healthcare provider to understand what they mean for your health.

Technical issues or errors during the biopsy or testing procedure could potentially affect the results. However, these instances are rare.

A positive test result should be discussed with the healthcare provider who ordered the test. They can provide information on what this means for your health and suggest appropriate next steps, which may include a referral to a specialist, such as a dermatologist or neurologist.

Yes, the IHC-S100 test can be used for both diagnosis of conditions and for monitoring the effectiveness of treatment.

Yes, the IHC-S100 test can be performed on individuals of any age, including children. However, the necessity and appropriateness of this test would be determined by a healthcare provider.

The IHC-S100 test is generally safe and poses minimal risks. However, as it involves a biopsy, there might be some risks associated with the biopsy procedure itself, such as bleeding or infection.

While uncommon, false positive or negative results can occur due to technical issues or errors during the testing procedure. Therefore, test results are often considered alongside other diagnostic information.

Whether or not the IHC-S100 test can be performed during pregnancy would depend on the individual's health status and the necessity of the test. This decision should be made in consultation with a healthcare provider.

The type of tissue sample needed for the IHC-S100 test depends on the suspected location of the disease. For example, a skin biopsy might be taken to check for melanoma, or a nerve biopsy could be performed if a nerve tumor is suspected.

A positive IHC-S100 result indicates the presence of the S100 protein in the tissue sample, which may suggest certain diseases, such as melanoma or nerve sheath tumors. However, the test alone is not enough for a definitive diagnosis, and further diagnostic procedures may be required.

There are no known medications that interfere with the IHC-S100 test. However, it's always important to discuss all medications and supplements you're currently taking with your healthcare provider prior to any medical testing.

The IHC-S100 test is a reliable diagnostic tool when used in conjunction with other tests and clinical findings. However, a single test should never be used as the sole basis for a diagnosis. A healthcare provider will interpret the test results in the context of the overall clinical picture.

The IHC-S100 test detects the presence of S100 protein, a substance produced by certain types of cells, regardless of lifestyle factors. However, maintaining a healthy lifestyle is always beneficial for overall health and well-being.

IHC - S100
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