IHC - ps2 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is required before this test. Patients can continue with their regular diet and medications.

₹ 2000


The IHC - PS2 (Estrogen Regulated Protein) Diagnostic Test is a pivotal investigation performed to determine the presence of PS2 protein in tissue samples. PS2, an estrogen-regulated protein, is often overexpressed in breast cancers that are estrogen receptor-positive (ER+). This protein plays an important role in the growth and proliferation of cancer cells.

The PS2 protein, also known as pS2 or Trefoil Factor 1 (TFF1), is one of several proteins that can become overexpressed in breast cancers, particularly those sensitive to hormones. Its detection can provide clinicians with valuable insights about the nature of the cancer and help guide decisions regarding the most suitable therapeutic strategies. Moreover, the presence of PS2 is also associated with a better prognosis in some cases.

Test Name IHC - ps2 (Estrogen Regulated Protein)
Sample Type Tissue
Preparations Required No special preparation is required before this test. Patients can continue with their regular diet and medications.
Report Time 5 days
Price in Hyderabad ₹ 2000

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Why is the IHC - PS2 Diagnostic Test important?

This test helps to determine whether a breast cancer is sensitive to hormones, specifically estrogen. The result can guide the choice of treatment, with hormone therapies being a potential option for PS2 positive cancers.

Is fasting required before the test?

No, fasting is not required for this test as it utilizes tissue samples, not blood.

When is this test recommended?

The IHC - PS2 test is typically recommended after a breast cancer diagnosis to assess the hormone sensitivity of the cancer and to aid in determining the most effective treatment strategy.

What does the test measure?

The test detects the presence of PS2 protein in breast cancer tissue. The presence of this protein can indicate that the cancer is likely to respond to hormone therapy.

How frequently should this test be done?

This test is usually conducted once, following a breast cancer diagnosis. However, further testing may be recommended based on individual treatment response and progress.

What are the normal values for the test?

As this test is performed on cancerous tissue, there aren't standard "normal" values. The presence or absence of PS2 proteins is interpreted by a healthcare professional in conjunction with other diagnostic information.

What precautions should I take before undergoing this test?

No specific precautions are required before this test. Patients should continue their usual diet and medications unless otherwise directed by their healthcare provider.

What factors can affect PS2 levels?

Age, genetic factors, and hormone therapy could potentially impact PS2 levels.

What should I do if the test results are abnormal?

Abnormal results should be discussed with the oncologist or the healthcare provider who ordered the test. They can provide an interpretation of the results and discuss the next steps in treatment.

Are there any risks associated with the test?

Risks associated with this test are typically related to the biopsy procedure, including discomfort, bruising, or potential infection at the biopsy site.

Can medication affect the test results?

Yes, hormone therapies and other medications could potentially affect the test results.

Does a positive result confirm the presence of breast cancer?

No, the IHC - PS2 test isn't used to diagnose breast cancer. It's used to determine hormone sensitivity after a cancer diagnosis.

What are the treatment options if the test result is positive?

A positive result indicates that the cancer cells may be sensitive to hormone therapies such as Tamoxifen or Aromatase inhibitors. Your healthcare provider will discuss suitable treatment options based on the test results and overall health condition.

Are there other tests usually performed alongside this one?

Yes, the IHC - PS2 test is usually done along with other tests like the Estrogen Receptor (ER) test, Progesterone Receptor (PR) test, and HER2 test to provide a comprehensive analysis of the cancer.

Who performs the IHC - PS2 test?

The test is performed by a pathologist in a laboratory setting.

Is this test recommended for both men and women?

Yes, while breast cancer is more common in women, men can also get it. If a man is diagnosed with breast cancer, the IHC - PS2 test can help in tailoring the treatment plan.

Can this test be used for cancers other than breast cancer?

The IHC - PS2 test is predominantly used in the context of breast cancer. However, PS2 protein expression may also be studied in other hormone-responsive cancers.

Can lifestyle changes impact the test results?

Lifestyle changes can improve overall health and aid in managing many types of illnesses, but the presence or absence of PS2 proteins in cancer cells is primarily determined by the cancer's inherent characteristics and is not directly impacted by lifestyle changes.

Is the IHC - PS2 test painful?

The test itself is not painful, but the biopsy procedure used to collect the tissue sample can cause some discomfort.

Can the IHC - PS2 test predict how well I will respond to treatment?

Yes, if the test is positive, indicating the presence of PS2 protein, the cancer is likely to respond to certain hormone therapies, leading to a potentially better treatment outcome.

In conclusion, the IHC - PS2 (Estrogen Regulated Protein) Diagnostic Test is a valuable tool for managing hormone-sensitive breast cancers. It is important to discuss the results with your healthcare provider to understand the implications and to decide on the most appropriate course of action. Open and continuous communication with your healthcare provider can lead to a better understanding of your condition and contribute to a more effective treatment plan.

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