IHC - PAX 5 | Test | Sprint Diagnostic

The PAX-5 Immunohistochemistry (IHC) test is a diagnostic procedure performed on tissue samples. The PAX-5 protein, also known as B-cell specific activator protein (BSAP), plays an essential role in B-cell development, a type of white blood cell. Abnormal expression of PAX-5 is associated with certain types of lymphomas and leukemias.

The PAX-5 IHC test uses antibodies that bind specifically to the PAX-5 protein, thereby facilitating its detection in tissue samples. This test can provide important diagnostic and prognostic information for certain types of cancers, especially hematologic malignancies.

  • Test Name: IHC - PAX 5
  • Sample Type: Tissue
  • Preparations Required: No specific preparation is needed for this test.
  • Report Time: 3 days

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Frequently Asked Questions

The PAX-5 IHC test plays a key role in diagnosing certain types of cancers, particularly lymphomas and leukemias that arise from B-cells. It helps in differentiating these cancers from other types, thus guiding treatment decisions.

No, fasting is not required for this test as it is performed on tissue samples, typically obtained through a biopsy or surgical procedure.

No specific preparation is required. The tissue sample is usually collected by a healthcare provider during a biopsy or surgical procedure.

This test is typically recommended when there's a suspicion of a hematologic malignancy, particularly a B-cell lymphoma or leukemia.

This test detects the presence or absence of the PAX-5 protein in tissue samples. Abnormal expression of PAX-5 can be indicative of certain types of cancers.

The frequency of this test depends on your doctor's advice and is generally conducted during the diagnostic process or when monitoring the response to cancer treatment.

The interpretation of the PAX-5 IHC test is based on the detection of the PAX-5 protein rather than a numerical value. The presence of PAX-5 in cells where it shouldn't normally be can suggest a cancerous condition.

As the test is performed on tissue samples, the main precautions relate to the biopsy or surgical procedure used to obtain the sample.

PAX-5 levels can be influenced by the presence of cancer, particularly B-cell lymphomas and leukemias. There are no known modifiable factors affecting PAX-5 expression.

If your PAX-5 IHC test results are abnormal, it's advisable to consult a hematologist or oncologist. They can guide you on the implications of the results and the subsequent steps to take.

While PAX-5 is primarily associated with B-cell malignancies, its expression may also be affected by other conditions. Therefore, the test result should be interpreted in conjunction with other clinical and diagnostic information.

PAX-5 is primarily expressed in B-cells. However, abnormal expression can occur in various types of cancers.

There are no specific medication restrictions before this test. However, always inform your doctor about any medications you're taking before any biopsy or surgical procedure.

No, this test requires a tissue sample, usually obtained via a biopsy or surgical procedure, and must be performed in a healthcare setting by a trained professional.

The PAX-5 IHC test is highly specific and reliable for detecting PAX-5 expression. However, its results should always be interpreted alongside other diagnostic tests and clinical findings for a comprehensive diagnosis.

The PAX-5 IHC test is a valuable tool in diagnosing and managing certain types of cancers. By understanding your test results and working closely with your healthcare provider, you can navigate your treatment journey more effectively.

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