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IHC - Microsatellite Instability for Colorectal Carcinoma MSH-2 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

The ImmunoHistoChemistry (IHC) - Microsatellite Instability (MSI) for Colorectal Carcinoma MSH-2 test is a specific diagnostic tool that aids in the diagnosis and management of colorectal cancer. It is a molecular method that measures the presence and activity of a protein called MSH-2, which is involved in DNA repair. The loss of this protein due to mutations is a hallmark of colorectal cancer and other cancers associated with Lynch Syndrome.

Colorectal cancer is the third most common type of cancer globally, and understanding its underlying genetic causes can significantly improve the management and prognosis of the disease. The MSH-2 protein is a part of the mismatch repair system that corrects errors in the DNA replication process. Mutations in the MSH-2 gene can lead to Microsatellite Instability, a condition marked by genetic hypermutability that significantly increases the risk of developing colorectal cancer.

  • Test Name: IHC - Microsatellite Instability for Colorectal Carcinoma MSH-2
  • Sample Type: Tissue
  • Preparations Required: No specific preparation is necessary for this test.
  • Report Time: 4 days

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

Signs include stable weight, clear skin, good digestion, regular bowel movements, healthy cholesterol and blood sugar levels, and sustained energy.

You can monitor liver health through blood tests, ultrasound imaging, FibroScan, and the fatty liver index.

The IHC - MSI for Colorectal Carcinoma MSH-2 test is used to detect the absence or malfunctioning of the MSH-2 protein in colorectal cancer tissues. The absence of this protein indicates the presence of Microsatellite Instability (MSI), which is a risk factor for colorectal cancer and other Lynch syndrome- related cancers.

No, fasting is not required for this test.

The frequency of this test depends on your doctor's advice. It is usually performed when colorectal cancer or Lynch syndrome is suspected.

A normal result shows the presence of the MSH-2 protein, indicating that the DNA mismatch repair system is likely functioning correctly. An abnormal result, characterized by the absence or malfunctioning of the MSH-2 protein, suggests the presence of MSI and an increased risk of colorectal cancer.

Yes. While primarily used for diagnosing colorectal cancer, this test can also help diagnose other cancers associated with Lynch syndrome, such as endometrial cancer.

No specific precautions are necessary for this test. However, make sure to inform your doctor about any medications or supplements you are currently taking.

Factors that can affect MSH-2 protein levels include genetic mutations, age, and certain lifestyle factors like diet and exposure to environmental toxins.

Normal values indicate the presence and normal functioning of the MSH-2 protein. However, the exact values may vary depending on the specific laboratory guidelines.

If your test results are abnormal, you should consult an oncologist or a genetic counselor for further advice and treatment options.

No specific preparations are needed for this test.

Certain medications might interfere with the test results. Therefore, it's important to inform your doctor about all medications, supplements, and vitamins you're currently taking before the test.

While lifestyle modifications can generally support overall health, they cannot significantly alter the genetic mutations that affect MSH-2 protein levels.

Low levels of MSH-2 protein suggest the presence of MSI, which is associated with an increased risk of developing colorectal cancer and other Lynch syndrome-related cancers.

Yes, this test is suitable for individuals of all ages. However, it is most commonly recommended for adults with a personal or family history of colorectal cancer or Lynch syndrome.

While this test cannot directly detect cancer, it can identify the presence of MSI, a condition that significantly increases the risk of developing colorectal cancer. Early detection of MSI can lead to early diagnosis and treatment of the disease.

The IHC - MSI for Colorectal Carcinoma MSH-2 test is a valuable tool in the early detection and management of colorectal cancer. By identifying the presence of Microsatellite Instability, it can provide important information that helps shape a patient's treatment plan and surveillance strategy. Early detection is key to successful treatment and improving survival rates. If you have a personal or family history of colorectal cancer or Lynch syndrome, consult your doctor about the potential benefits of this test.

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