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Immunohistochemistry LAMBDA Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Immunohistochemistry (IHC) is a laboratory technique used to visualize and analyze proteins in tissue samples. The LAMBDA test, part of IHC, focuses on detecting lambda light chains, which are components of antibodies produced by the immune system. In a healthy individual, there is a balance between two types of light chains: kappa and lambda. However, in certain diseases, such as lymphomas and multiple myeloma, this balance may be disrupted.

Lambda light chains are of particular interest when it comes to diagnosing and monitoring plasma cell disorders and B-cell malignancies. By detecting the presence and quantity of lambda light chains within a tissue sample, clinicians can glean valuable information about the state of the immune system and whether any abnormalities may indicate an underlying disorder.

  • Test Name: IHC - Langerin
  • Sample Type: Tissue
  • Preparations Required: No special preparation is required for this test.
  • Report Time: 3 days

Home Sample Collection Process

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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

The IHC - LAMBDA test is a laboratory analysis that utilizes antibodies to detect the presence of lambda light chains in tissue samples. This test is particularly helpful in diagnosing diseases such as lymphomas and multiple myeloma, where there is an overproduction of lambda light chains.

Understanding the levels of lambda light chains is crucial for diagnosing and monitoring plasma cell disorders and B-cell malignancies. Abnormal levels can indicate an immune system disorder, which requires further investigation and potentially treatment.

No, fasting is not required for this test. The test is performed on tissue samples, usually obtained through a biopsy, and there are no dietary restrictions.

This test is usually ordered by a healthcare provider if there are symptoms or laboratory findings suggestive of plasma cell disorders or B-cell malignancies, or to monitor the progress of these diseases.

The IHC - LAMBDA test provides information about the presence and quantity of lambda light chains in tissue samples. This information can help in the diagnosis of certain diseases and in evaluating the immune system’s response.

The frequency of the IHC - LAMBDA test is determined by your healthcare provider and is based on your medical history, underlying health conditions, and the specific reason for testing.

Normal values can vary depending on the laboratory that analyzes the test. Generally, in a balanced immune system, there is a nearly equal number of kappa and lambda light chains. However, your healthcare provider will interpret the results in the context of your overall health and other test results.

There are no specific precautions needed for the IHC - LAMBDA test. It is, however, important to inform your healthcare provider of any medications or supplements you are taking, as they could potentially interfere with test results.

Factors that can affect lambda light chain levels include infections, inflammatory diseases, kidney diseases, and hematological disorders such as multiple myeloma or lymphomas.

Non-modifiable factors include genetic predisposition to certain diseases and age.

If the levels of lambda light chains are too high or too low, it may indicate an underlying disorder such as a plasma cell disorder or B-cell malignancy. In such cases, additional testing will be required to confirm the diagnosis.

If your test results are abnormal, you should consult the healthcare provider who ordered the test. This could be a hematologist or an oncologist, depending on your condition.

No, the IHC - LAMBDA test requires a tissue sample, usually obtained through a biopsy, which must be performed in a clinical setting by a healthcare professional.

The risks associated with the IHC - LAMBDA test are mainly related to the biopsy procedure. There may be risks of infection, bleeding, or discomfort at the biopsy site.

While the test alone cannot diagnose cancer, it can help provide crucial information about an individual’s immune system and detect abnormalities that may suggest diseases like lymphoma or multiple myeloma.

As part of the diagnostic journey, the IHC - LAMBDA test is a crucial tool in providing valuable information about a patient's health. Although the test alone is not enough for a full diagnosis, it significantly contributes to the bigger picture, helping medical professionals make informed decisions regarding a patient's health. Understanding what to expect during the test can ease any concerns and aid in better cooperation during the diagnostic process, leading to a smoother patient experience.

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