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Immunohistochemistry IHC Desmin Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Immunohistochemistry (IHC) is a diagnostic technique that involves the use of antibodies to detect the presence of specific proteins in tissue samples. The presence or absence of these proteins can help pathologists and doctors to diagnose various diseases, particularly cancers. One such protein that can be detected using IHC is Desmin.

Desmin is a type of intermediate filament protein found primarily in muscle cells. In the context of pathology, desmin is often used as a marker to identify tumors that originate from or differentiate towards muscle cells, also known as myogenic tumors. These can include rhabdomyosarcoma, leiomyosarcoma, and other types of soft tissue sarcomas.

However, the detection of Desmin isn't exclusive to myogenic tumors; it can also be found in other conditions or tumor types, albeit less commonly. It's crucial to interpret the results of an IHC - Desmin test in the context of the overall clinical picture and other test results.

  • Test Name: IHC - Desmin
  • Sample Type: Tissue
  • Preparations Required: No special preparation is needed for this test.
  • Report Time: 3 days

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Reporting of the sample at lab
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Frequently Asked Questions

The IHC - Desmin test is used to identify the presence of Desmin proteins in tissue samples. These proteins are most often found in muscle cells, and their presence can suggest a muscle origin of a tumor.

No, fasting is not required for the IHC - Desmin test. The test involves analyzing a tissue sample, typically obtained through a biopsy or during a surgical procedure.

A positive result indicates the presence of Desmin proteins in the tissue sample. This could suggest a muscle origin of the tumor, but it's crucial to interpret this result in the context of the patient's clinical picture and other test results.

The tissue sample is typically obtained through a biopsy or during a surgical procedure. The specific method of obtaining the sample will depend on the location and nature of the suspected tumor.

There is no specific preparation required for the IHC - Desmin test. However, you should inform your healthcare provider about any medications or supplements you are taking, as these could potentially interfere with the test results.

The test itself does not pose any risks. However, the procedure to obtain the tissue sample may carry potential risks, such as infection or bleeding.

While the IHC - Desmin test can suggest a muscle origin of a tumor, it does not specifically identify the type of cancer. Other diagnostic tests will be needed to confirm the type of cancer.

Certain factors may affect the results of the IHC - Desmin test, including the quality of the tissue sample, the method of sample preparation, and the specific technique used in the IHC procedure.

Abnormal results should be discussed with your healthcare provider. They will interpret the results in the context of your overall health, symptoms, and other test results. Further testing may be necessary to confirm a diagnosis.

The frequency of the IHC - Desmin test will depend on the individual's clinical situation. Your healthcare provider will determine when and how often this test should be performed.

Yes. Non-tumor conditions involving muscle damage or inflammation may also positive Desmin staining. Always consult with your healthcare provider for a comprehensive understanding of your results.

Usually, a pathologist performs the analysis and interpretation of the test. However, your oncologist or the doctor who ordered the test will discuss the results with you and explain their implications.

Desmin is a structural protein in muscle cells and is not influenced by lifestyle factors like diet or exercise. Its expression is primarily affected by pathological changes in the body.

Non-modifiable factors would include any genetic or inherent characteristics that influence Desmin production, such as certain gene mutations or underlying diseases affecting the muscle tissue.

Yes, the IHC - Desmin test is often performed along with a panel of other immunohistochemical tests, and may also be accompanied by other diagnostic procedures like CT scans, MRIs, or PET scans to get a comprehensive picture of the patient's health condition.

This IHC - Desmin test provides valuable information to healthcare providers in identifying the nature of a tumor, particularly when a muscle origin is suspected. Although it provides significant insights, it is merely a part of the diagnostic puzzle. Other tests and clinical information will be used to make a definitive diagnosis and develop a treatment plan. Always maintain an open line of communication with your healthcare team to understand the results and the next steps in your care.

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