Immunohistochemistry IgG-4 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No specific patient preparation instructions are required as the test is performed on a tissue sample collected through a biopsy.

₹ 2500

The Immunohistochemistry (IHC) - IgG-4 test is a critical diagnostic tool in modern medicine, playing a vital role in identifying and diagnosing various immune-related disorders. IHC is a lab technique that involves the detection of specific proteins, such as antibodies, in cells of a tissue section. It is a powerful method used to understand the tissue distribution and localization of biomarkers and differentially expressed proteins in cells of tissues.

IgG-4, or Immunoglobulin G4, is a subtype of the IgG antibody, which plays a pivotal role in our immune response. The IHC - IgG-4 test is crucial in identifying the presence of IgG-4 in tissue samples. It is especially important in diagnosing conditions like IgG-4 related disease, which is characterized by tumorous swelling in various parts of the body due to infiltration of IgG-4 positive plasma cells.

Test Name IHC - IgG-4
Sample Type Tissue
Preparations Required No specific patient preparation instructions are required as the test is performed on a tissue sample collected through a biopsy.
Report Time 3 days
Price in Hyderabad ₹ 2500

What is the IHC - IgG-4 test?

The IHC - IgG-4 test is a diagnostic procedure designed to detect the presence of the IgG-4 antibody in tissue samples. The test employs a lab technique known as immunohistochemistry, which uses specific antibodies to bind and detect certain proteins in tissue samples.

Why is the IHC - IgG-4 test important?

The IHC - IgG-4 test is vital because it aids in diagnosing diseases that are associated with an overactive IgG-4 response, such as IgG-4 related disease. This condition leads to an overabundance of IgG-4 antibodies, causing inflammation and fibrosis in different body organs.

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How is the IHC - IgG-4 test performed?

This test is performed on a tissue sample, typically obtained through a biopsy. The sample is treated with an antibody that binds specifically to IgG-4. The bound antibodies are then detected using a microscope, indicating the presence of IgG-4 in the tissue.

What does a positive IHC - IgG-4 test indicate?

A positive result in an IHC - IgG-4 test means that the tissue sample contains IgG-4 antibodies. This could be an indication of an underlying condition associated with high levels of IgG-4, such as IgG-4 related disease.

Is fasting required for this test?

No, fasting is not necessary for this test. It is performed on a tissue sample, which is typically collected through a biopsy.

How often should this test be done?

This test is not performed routinely but is requested by your doctor based on your symptoms, medical history, and preliminary diagnostic results.

What are normal values for this test?

Normal tissues should have few IgG-4 positive cells. However, what constitutes "normal" can vary depending on the specific clinical context and the laboratory performing the test.

What precautions should be taken before the test?

There are no specific precautions to take before the test itself. However, there may be instructions regarding the biopsy procedure used to collect the tissue sample.

Which doctor should I consult if I get an abnormal result?

If you get an abnormal result, you should consult with the doctor who ordered the test, which might be an immunologist, a rheumatologist, or a pathologist, depending on your symptoms and medical history.

What factors can affect the test results?

The main factors that could affect the results of the IHC - IgG-4 test are technical issues related to the biopsy procedure or the processing of the tissue sample.

Is the test painful?

The test itself is not painful. However, the procedure to collect the tissue sample (biopsy) may cause some discomfort or pain.

Can medications affect the result of this test?

There are no specific medications known to affect the results of this test. However, it is always a good idea to inform your healthcare provider of all the medications you are currently taking.

Is IgG-4 only present in the immune system?

IgG-4 is an antibody that is part of the immune system, and it is produced by plasma cells, a type of immune cell. However, it can be found in different tissues if there is an immune response or inflammation.

Is the test accurate?

Yes, the IHC - IgG-4 test is a reliable method of detecting IgG-4 in tissue samples, but its interpretation should be considered alongside other clinical findings and diagnostic tests.

Can this test be done at home?

No, this test cannot be done at home. It requires a tissue sample that needs to be collected by a healthcare professional and processed in a laboratory.

The IHC - IgG-4 test is a valuable asset in our diagnostic toolkit. While it may not be a household name, its role is crucial in understanding our body's immune response and identifying specific medical conditions. As always, maintaining open communication with your healthcare provider will allow you to fully understand and navigate your health journey.

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