IHC - GLYCOPHORIN-A Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Glycophorin-A, also known as GPA or CD235a, is a protein predominantly found on the surface of red blood cells. The IHC - Glycophorin-A diagnostic test utilizes the immunohistochemistry technique to detect the presence of this protein in tissue samples. It is particularly useful in diagnosing certain blood disorders and differentiating between different types of tumors, especially in cases where the origin of the tumor is uncertain. By targeting the Glycophorin-A protein with specific antibodies, this test helps in the characterization of erythroid cells and neoplasms, aiding in more informed clinical decision-making.

Glycophorin-A is crucial in maintaining the structural integrity of red blood cells and plays a role in the cell's interaction with its surroundings. The detection of this protein can provide information about erythrocytic lineage in the case of various hematological diseases, including anemias and myelodysplastic syndromes. Additionally, it is used in characterizing certain tumors.

  • Test Name: IHC - GLYCOPHORIN-A
  • Sample Type: Tissue
  • Preparations Required: No specific instructions are required for this test.
  • Report Time: 3 days

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Reporting of the sample at lab
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Frequently Asked Questions

This test detects the presence of Glycophorin-A, a protein found on the surface of red blood cells, in tissue samples.

It is used to diagnose certain blood disorders, such as anemia, and to help differentiate between different types of tumors, especially if the origin of the tumor is unclear.

No, fasting is not required for the IHC - Glycophorin-A test.

The test is usually performed on tissue samples where the presence of red blood cells or their precursors is suspected or needs to be confirmed.

The level of discomfort or pain depends on the procedure used to obtain the tissue sample for testing.

The presence of Glycophorin-A in the tissue sample indicates the presence of red blood cells or their precursors. This can be indicative of a blood disorder or a certain type of tumor.

The test is performed using immunohistochemistry, where antibodies specific to Glycophorin-A are applied to a tissue sample. The antibodies are tagged with a dye, and the presence of Glycophorin-A is visualized under a microscope.

The risks are generally related to the procedure used to obtain the tissue sample and can include infection, bleeding, or reaction to anesthesia.

Certain medical conditions, such as anemia, leukemia, or erythroid hyperplasia, can affect the levels of Glycophorin-A. Additionally, certain medications might have an impact.

Normal levels can vary, but Glycophorin-A is typically expressed on the surface of red blood cells. Increased expression in other cell types may indicate a pathological condition.

Abnormal levels may indicate a blood disorder or a tumor. Further tests and consultations with a doctor will be necessary to establish a diagnosis.

If Glycophorin-A levels are abnormal, consulting a hematologist or an oncologist is recommended.

This test alone cannot diagnose cancer but can be used in conjunction with other tests and clinical information to help characterize tumors and potentially identify their origin.

of treatment for blood disorders? It can be used as part of a series of tests to monitor the status of erythroid cells in blood disorders and evaluate the effectiveness of treatment.

The frequency of this test depends on the clinical scenario and the doctor's recommendation.

While it is primarily used for diagnostic purposes, it can also be used in research and to monitor the progression of certain diseases and the response to therapy.

blood disorders or tumors? Yes, there are alternative tests such as complete blood counts, flow cytometry, and other immunohistochemistry tests targeting different proteins. The choice of test depends on the clinical situation and the information needed.

Yes, certain medications, especially those affecting blood cells or the immune system, may affect the results. It's important to inform the doctor about any medications you are taking.

test? There are no specific age-related considerations, but the prevalence of certain blood disorders and tumors may vary with age, which can influence the interpretation of the test results.

The next step after receiving the results is to consult with your doctor. Depending on the results, your doctor may recommend additional tests or discuss treatment options if a diagnosis is made.

Understanding the role of Glycophorin-A and its implications in various diseases is crucial. This protein, which is majorly found in red blood cells, can provide significant insights when its presence is evaluated in tissue samples through the IHC - Glycophorin-A diagnostic test. The information obtained is not only vital for the diagnosis but also for the management and monitoring of several blood disorders and tumors.

Ensuring proper consultation with your doctor and understanding the importance of this test is key. Your doctor can guide you through the results and work on a plan tailored to your health needs, whether it is further testing, starting treatment, or ongoing monitoring. Through the collaboration of patient and doctor, optimal health outcomes can be achieved.

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