IHC - GATA-3 - Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is needed for the IHC - GATA-3 test

₹ 2500


GATA-3 is a transcription factor crucial for the development and differentiation of various cell types, including T-lymphocytes and some breast cells. In clinical diagnostics, immunohistochemistry (IHC) testing for GATA-3 can be used as a marker to identify certain cancers, particularly breast cancer and urothelial carcinoma. The IHC technique involves using antibodies to detect the presence of specific proteins in tissue samples, such as GATA-3 in this instance. The test is performed on tissue samples obtained through biopsy or surgery

One of the primary applications of the IHC GATA-3 test is to identify the origin of metastatic cancer. Since GATA-3 is usually expressed in breast cancer and urothelial carcinoma, the presence of GATA-3 in a tumor can suggest that the cancer originated from these tissues

Test Name IHC - GATA-3
Sample Type Tissue
Preparations Required No special preparation is needed for the IHC - GATA-3 test
Report Time 3 Days
Price in Hyderabad ₹ 2500

What is the importance of the IHC - GATA-3 test?

The IHC GATA-3 test is essential for diagnosing and characterizing certain types of cancers, especially breast cancer and urothelial carcinoma. It helps in identifying the origin of metastatic tumors and may contribute to determining the most effective treatment strategy.

Is fasting required for the IHC - GATA-3 test?

No, fasting is not required for the IHC - GATA-3 test. The test is performed on tissue samples obtained through biopsy or surgery.

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What information does the IHC - GATA-3 test provide?

The IHC - GATA-3 test provides information on the presence and expression level of the GATA-3 protein in tissue samples. This data can be indicative of certain types of cancer, such as breast cancer and urothelial carcinoma.

How often should the IHC - GATA-3 test be performed?

The frequency of the IHC - GATA-3 test depends on the clinical scenario and your doctor's recommendations. It is generally performed when there is suspicion of cancer or when characterizing a known tumor.

What are the normal values for GATA-3?

In normal tissue, GATA-3 expression can vary. In the context of cancer diagnosis, the presence or high expression of GATA-3 may be indicative of breast cancer or urothelial carcinoma.

What precautions should be taken before undergoing the IHC - GATA-3 test?

No specific precautions are required. It's important to communicate your medical history to your doctor, especially if you have a history of cancer.

What factors can affect the levels of GATA-3?

Factors that can affect the levels of GATA-3 include the type of tissue, the presence of cancer (especially breast cancer or urothelial carcinoma), and certain genetic factors.

What doctor should be consulted in case of abnormal GATA-3 levels?

If the IHC - GATA-3 test results are abnormal, it is advisable to consult an oncologist who specializes in cancer care.

Can GATA-3 be used to monitor the response to cancer treatment?

Yes, in some cases, GATA-3 may be used to monitor the response to treatment in breast cancer and urothelial carcinoma.

Are there any risks associated with the IHC - GATA-3 test?

The test itself has no risks, but obtaining a tissue sample for testing through biopsy or surgery carries typical procedural risks such as infection or bleeding.

Can GATA-3 levels change over time?

Yes, GATA-3 levels can change, especially in response to cancer treatment.

What is the role of GATA-3 in the body?

GATA-3 is a transcription factor that is essential for the development and differentiation of various cells, including T-lymphocytes and some cells in the breast.

Can GATA-3 be used to differentiate between different types of cancer?

Yes, GATA-3 is especially useful in differentiating between breast cancer and urothelial carcinoma from other types of cancers.

Are there alternatives to the IHC - GATA-3 test for diagnosing breast cancer or urothelial carcinoma?

Yes, there are several diagnostic methods for breast cancer and urothelial carcinoma, including mammography, ultrasonography, and other biomarker tests.

What are the implications of high GATA-3 levels in a tissue sample?

High levels of GATA-3 in a tissue sample may indicate the presence of breast cancer or urothelial carcinoma, but it is important to interpret the results in the context of other clinical findings and tests.

Is the IHC - GATA-3 test always definitive in diagnosing breast cancer or urothelial carcinoma?

No, while the IHC - GATA-3 test is highly useful, it is not always definitive. The results should be interpreted in conjunction with other diagnostic tests and clinical findings.

Is GATA-3 only associated with breast cancer and urothelial carcinoma?

While GATA-3 is most commonly associated with breast cancer and urothelial carcinoma, it can also be expressed in other types of tumors. It’s important for the doctor to consider the whole clinical picture.

Can GATA-3 be used to determine the aggressiveness of breast cancer or urothelial carcinoma?

GATA-3 may provide some information regarding tumor characteristics, but other factors and tests are generally used to determine the aggressiveness of a tumor.

Does the level of GATA-3 expression correlate with the stage of the cancer?

The level of GATA-3 expression can sometimes correlate with the stage of breast cancer, but this is not always the case. The stage of cancer is usually determined by combining various factors including tumor size, lymph node involvement, and the presence of metastasis.

How is the tissue sample for the IHC - GATA-3 test obtained?

The tissue sample for the IHC - GATA-3 test is usually obtained through a biopsy, which involves removing a small amount of tissue from the tumor. In some cases, the tissue may be obtained during surgery.

Can GATA-3 expression change after treatment?

Yes, GATA-3 expression can change in response to treatment. Monitoring GATA-3 levels can sometimes be helpful in evaluating the effectiveness of the treatment.

Is the IHC - GATA-3 test painful?

The test itself is not painful, but the biopsy procedure to obtain the tissue sample can cause discomfort. Pain relief and sedation are often used to minimize discomfort during the procedure.

The IHC - GATA-3 test is an important diagnostic tool that is particularly useful in identifying and characterizing breast cancer and urothelial carcinoma. It plays a significant role in the management of these conditions and may inform treatment decisions. Understanding the importance of this test and what the results may indicate is crucial for patients in discussing options and making informed decisions in collaboration with their doctor.

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