IHC - DOG-1 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No special preparation is needed for this test.

₹ 2500


Immunohistochemistry (IHC) is a powerful tool used in pathology to visualize the presence of specific proteins in tissues. The IHC test for DOG-1 (Discovered on GIST-1) is a specific test used to detect the presence of the DOG-1 protein in tissues. This test plays a vital role in the diagnosis of gastrointestinal stromal tumors (GISTs), which are a type of tumor that begins in the digestive tract's specialized nerve cells.

The DOG-1 protein is typically overexpressed in GISTs. Hence, the detection of this protein can assist pathologists in confirming a diagnosis of GIST. GISTs are rare, but they are the most common mesenchymal tumors of the gastrointestinal tract. Early and accurate diagnosis is crucial to guide treatment and improve patient outcomes.

Test Name IHC - DOG-1
Sample Type Tissue
Preparations Required No special preparation is needed for this test.
Report Time 3 days
Price in Hyderabad ₹ 2500

What is the importance of the IHC DOG-1 test?

The IHC DOG-1 test helps to confirm the diagnosis of GIST. While GISTs are rare, early detection is crucial because these tumors can grow quickly and spread to other parts of the body.

Is fasting required for the IHC DOG-1 test?

No, fasting is not required for the IHC DOG-1 test.

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Is there any specific preparation for the IHC DOG-1 test?

No special preparation is required before the test. The test uses a tissue sample that is usually obtained through a biopsy.

When should I get the IHC DOG-1 test?

Your doctor may recommend the IHC DOG-1 test if you have a mass or tumor in your digestive tract that may be a GIST. The test can help confirm the diagnosis.

What information does the IHC DOG-1 test provide?

The IHC DOG-1 test can identify the presence and location of the DOG-1 protein in a tissue sample. A positive result supports a diagnosis of GIST.

How often should I have the IHC DOG-1 test?

The frequency of the IHC DOG-1 test depends on your medical condition. It's not a routine test but is used when there's a suspicion of GIST.

What are the normal values for the IHC DOG-1 test?

In a normal tissue sample, DOG-1 is not typically expressed. Therefore, a positive result may suggest the presence of GIST.

Are there any precautions I should take?

There are no specific precautions to take for the IHC DOG-1 test. However, you should always discuss any concerns with your healthcare provider.

What factors can affect the levels of DOG-1?

DOG-1 expression is inherent to certain cells and is not typically influenced by external factors. However, some technical aspects of the test, such as tissue preservation and handling, may impact the test results.

Which doctor should I consult in case of an abnormal DOG-1 value?

If the IHC DOG-1 test result is abnormal, you should consult with an oncologist or a gastroenterologist who specializes in gastrointestinal cancers.

Can DOG-1 expression be found in other types of cancer?

While DOG-1 is most commonly associated with GISTs, some studies suggest it may also be present in other types of cancers. However, further research is needed in this area.

Is the IHC DOG-1 test accurate?

The IHC DOG-1 test is highly accurate in identifying DOG-1 expression, but it's only one tool that doctors use in diagnosing GISTs. Other tests and the overall clinical picture are also considered.

What if my test results are negative, but I still have symptoms?

If your test results are negative but you continue to experience symptoms, your doctor may recommend additional tests. Remember, the IHC DOG-1 test is just one tool used in diagnosis.

Can medications affect the results of the IHC DOG-1 test?

No, medications should not affect the results of the IHC DOG-1 test.

Does the IHC DOG-1 test alone confirm the diagnosis of GISTs?

The IHC DOG-1 test is a significant part of the diagnostic process, but other factors, including the tumor's location, size, and growth pattern, are also considered in making a diagnosis.

What's the next step after a positive IHC DOG-1 test result?

If your IHC DOG-1 test result is positive, it's crucial to follow up with your doctor for further diagnostic tests and appropriate treatment. Treatment strategies for GISTs can include surgery, targeted therapy, and other therapies based on the specific characteristics of your tumor.

Can lifestyle changes influence the results of an IHC DOG-1 test?

The IHC DOG-1 test identifies the presence of the DOG-1 protein within tissue samples. As such, lifestyle changes will not directly affect test results. However, a healthy lifestyle may contribute to overall well-being and disease prevention.

Are there any risks associated with the IHC DOG-1 test?

The test itself carries no direct risks as it's performed on a tissue sample already collected, often via biopsy. However, a biopsy procedure has its risks, including infection and bleeding. Your doctor will explain these to you before the procedure.

Are there alternatives to the IHC DOG-1 test for diagnosing GISTs?

Yes, there are other methods used in conjunction with IHC testing to diagnose GISTs. These include genetic testing for specific mutations common in GISTs and other types of IHC tests to detect different proteins.

Does insurance typically cover the cost of the IHC DOG-1 test?

Insurance coverage for the IHC DOG-1 test can vary. It's advisable to check with your insurance provider to understand the coverage for this specific test.

The DOG-1 test, while specific, is one piece of the puzzle when it comes to diagnosing GISTs. Being well-informed about the process can help you feel more comfortable and enable you to actively participate in your healthcare decisions. Remember, you are the most important member of your healthcare team, and open communication with your doctors can significantly contribute to better health outcomes.

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