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IHC - Cytokeratin - Pan Keratin

Immunohistochemistry (IHC) tests like the Cytokeratin - Pan Keratin test are essential tools for pathologists. They help in detecting and identifying different types of cancers by analyzing protein expressions in tissue samples. The Cytokeratin - Pan Keratin test particularly looks for a range of cytokeratin proteins, key structural components of epithelial cells.


  • Test NameIHC - Cytokeratin - Pan Keratin
  • Sample TypeTissue
  • Preparations RequiredNo special preparation is required for this test.
  • Report Time3 days

Cytokeratins belong to a family of proteins known as intermediate filaments that play a crucial role in the structural integrity of epithelial cells. The existence of these proteins in different cell types varies, hence their expression can be a helpful indicator in recognizing the origin of certain types of tumors, particularly those originating from epithelial cells, like carcinomas.

The Pan Keratin test assesses the expression of a wide spectrum of cytokeratins in a tissue sample. It's an immunohistochemistry test where antibodies that bind to various cytokeratins are used. This helps in visualizing their presence and determining the origin of an unclassified tumor, hence providing critical information for accurate diagnosis and treatment.

Home Sample Collection Process
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Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

This test helps in the identification of various cytokeratins in a tissue sample. It's particularly useful in diagnosing carcinomas or other tumors of epithelial origin.

This test is crucial when a tumor's origin is hard to determine. It assists in identifying whether the tumor is of epithelial origin, influencing the treatment approach.

A tissue sample is usually collected via a biopsy. This sample is then treated with a pan-keratin antibody stain and observed under a microscope for cytokeratin presence.

There are no special preparations needed before the test. However, informing your healthcare provider about your medical history and ongoing medications is advisable.

The risks associated with this test mainly stem from the biopsy procedure to collect the tissue sample. These can include potential bleeding, infection, or reactions to anesthesia.

Presence of cytokeratins in your tissue sample could indicate a tumor of epithelial origin. However, the test results will be analyzed in conjunction with your other medical data for a comprehensive diagnosis.

This test is mainly used for diagnosing carcinomas or other tumors originating from epithelial cells.

Since this test doesn't involve radiation or harmful substances, it's generally safe for pregnant or breastfeeding women. However, the biopsy procedure's risks still apply.

The pathologist will assess the presence and amount of various cytokeratins in the tissue sample. Their presence could point towards a carcinoma or other epithelial cell-derived tumors.

If the test result is positive, it suggests the presence of cytokeratins, indicating a possible tumor of epithelial origin. Further tests may be needed to confirm the diagnosis and guide treatment.

The frequency of this test depends on your specific medical situation and the recommendations of your healthcare provider. It may be done periodically to monitor the progress of treatment.

Other tests like molecular genetic tests and various imaging tests can be used alongside or as alternatives to the IHC - Cytokeratin - Pan Keratin test.

Normal values may depend on the specific laboratory that analyzes the test. Generally, the absence of cytokeratins or low expression in non-epithelial tissues is considered normal.

If your test results are abnormal, you should consult an oncologist or a pathologist for a comprehensive evaluation and appropriate treatment plan.

Lifestyle factors do not typically affect the expression of cytokeratins. Their presence is more commonly associated with certain pathological conditions like tumors of epithelial origin.

No, the IHC - Cytokeratin - Pan Keratin test does not involve any radiation exposure. It's a staining process that identifies specific proteins in the tissue sample.

Yes, it can be utilized to monitor the treatment effectiveness of certain types of cancer. Changes in cytokeratin expression levels can indicate how well the body is responding to therapy.

Other immunohistochemistry tests, as well as molecular genetic tests, may be performed alongside this one to give a more comprehensive understanding of the tumor.

The test can help identify the presence and origin of metastatic tumors by recognizing the cytokeratins often found in carcinomas.

Yes, the expression of different types of cytokeratins can provide information about the type of carcinoma. However, other diagnostic procedures may be required for a more detailed understanding.

Immunohistochemistry tests like the Cytokeratin - Pan Keratin are significant parts of the diagnostic process in oncology. It is essential to communicate openly with your healthcare provider and understand what your test results mean for your health status. Remember, every test forms part of the bigger picture of your health, and it is the combination of these tests, your symptoms, and your medical history that leads to a final diagnosis.

IHC - Cytokeratin - Pan Keratin
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