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Immunohistochemistry CDX2 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

The CDX2 test, a type of Immunohistochemistry (IHC) test, is performed to identify the CDX2 protein in tissue samples. CDX2 is a protein expressed in the nuclei of cells in the intestinal lining. This protein plays a significant role in regulating the development and maintenance of the intestine. The test is used primarily by pathologists to help diagnose and classify tumors, specifically gastrointestinal tumors. It is especially useful in identifying colorectal cancer.

Immunohistochemistry, the method used in the CDX2 test, is a laboratory technique that utilizes the principle of antibodies binding specifically to antigens in biological tissues. It's a crucial tool in cellular biology, diagnostic pathology, and various research applications. The antibodies used in IHC are tagged with a color-producing enzyme to visibly label the protein of interest—in this case, the CDX2 protein.

  • Test Name: (IHC) - CDX2
  • Sample Type: Tissue
  • Preparations Required: No specific preparation is required for this test.
  • Report Time: 3 days

Home Sample Collection Process

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Reporting of the sample at lab
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Frequently Asked Questions

The IHC - CDX2 test is used to determine the presence and location of the CDX2 protein in tissue samples. Its detection is valuable in diagnosing and distinguishing gastrointestinal tumors, primarily colorectal cancer, from other types of cancer.

This test is performed on a tissue sample, usually taken during a biopsy, surgery, or autopsy. The sample is treated with antibodies that bind to the CDX2 protein, if present. The antibodies are tagged with a dye to make the protein visible under a microscope.

No special preparation is needed for the IHC - CDX2 test. However, your doctor will provide you with instructions to follow before your procedure if a biopsy or surgical procedure is necessary to obtain the tissue sample.

The IHC - CDX2 test itself carries no risks. However, there may be risks associated with the procedure used to obtain the tissue sample, such as infection, bleeding, or reaction to anesthesia.

A positive result means that the CDX2 protein is present in the sample, which could indicate a gastrointestinal tumor, such as colorectal cancer. Further tests will be required to confirm the diagnosis and determine the best course of treatment.

While the CDX2 protein is typically associated with gastrointestinal tumors, it may be expressed in other types of cancer. Therefore, a positive result does not necessarily mean the patient has colorectal cancer.

A negative result means that the CDX2 protein was not detected in the sample. This result could indicate that the patient does not have a gastrointestinal tumor, or the tumor does not express the CDX2 protein.

The IHC - CDX2 test is highly reliable when performed and interpreted by experienced laboratory professionals. However, it is often used in conjunction with other diagnostic tests for a comprehensive evaluation.

Factors such as the quality of the tissue sample, timing of the sample collection, and the method of sample preservation can influence the test results.

Typically, the results of the IHC - CDX2 test are available within a week. However, the exact timeframe can vary depending on the laboratory.

Whether you need to repeat the IHC - CDX2 test depends on various factors, such as the quality of the initial sample and your doctor's evaluation of your symptoms and medical history.

If your IHC - CDX2 test result is positive, your doctor will likely order additional tests to confirm the diagnosis and determine the best course of treatment.

The IHC - CDX2 test is typically ordered for patients with suspected gastrointestinal tumors. Your doctor will determine if this test is appropriate for you based on your symptoms, medical history, and physical examination.

The presence or absence of CDX2 can provide valuable prognostic information. Research has shown that patients with colorectal cancer that express CDX2 have a better prognosis than those without CDX2 expression.

If you have abnormal IHC - CDX2 test results, you should consult with a medical oncologist or a gastroenterologist. They can interpret the results and guide you on the next steps for diagnosis and treatment.

The IHC - CDX2 test is a valuable tool in diagnosing gastrointestinal tumors. However, it's not the only method used. Alternative methods may include other IHC tests, molecular tests, or imaging procedures like CT scans, MRIs, and PET scans. The choice of method depends on the clinical situation and the physician's discretion.

No, a negative IHC - CDX2 test does not necessarily rule out all types of cancer. It means that the specific protein, CDX2, was not detected in the tested tissue. The absence of this protein could indicate that the patient does not have a gastrointestinal tumor, or that the tumor does not express CDX2. Other tests may be necessary to rule out or diagnose different types of cancer.

A positive IHC - CDX2 result is typically associated with certain types of tumors, particularly those in the gastrointestinal tract. However, a positive result does not necessarily mean that the individual has cancer. The test may sometimes yield false-positive results, due to factors like sample contamination, technical errors, or other rare conditions. Any positive result should be discussed with a healthcare provider for a comprehensive interpretation.

The procedure to collect a tissue sample depends on the source of the tissue. It may involve a biopsy, a surgical procedure, or even an autopsy. Most of the time, you can expect to be under local or general anesthesia to minimize discomfort. Your doctor will explain the procedure to you beforehand and guide you through the necessary preparations.

You should follow your doctor's instructions regarding eating and drinking before the procedure. In some cases, you may need to fast for a certain period. The specific instructions will depend on the method used to collect the tissue sample.

The IHC - CDX2 test is typically performed on a tissue sample from the gastrointestinal tract, often obtained through a biopsy. However, it may also be performed on tissue from other areas if gastrointestinal cancer spread is suspected.

In conclusion, the IHC - CDX2 test is an important tool in diagnosing and understanding gastrointestinal tumors. As with all tests, it is most effective when used in combination with other diagnostic procedures and in the context of the patient's overall medical profile. While the presence of the CDX2 protein can indicate certain types of cancer, it is not a definitive diagnosis. Further tests will be necessary to confirm the diagnosis and guide treatment decisions. Regular communication with your healthcare provider is crucial in ensuring the best possible outcomes.

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