Immunohistochemistry CD8 Test, Price, Normal Range | Sprint Diagnostics Hyderabad
Patient Preparing : No specific instructions are required before the test.
The Immunohistochemistry (IHC) test for CD8 is a laboratory procedure that is used to visualize the presence and distribution of CD8 protein in a tissue sample, usually a biopsy. CD8 is a marker found on the surface of cytotoxic T cells, a type of white blood cell that plays a crucial role in the immune system's ability to fight off infections and diseases.
The test uses antibodies that specifically bind to the CD8 protein. When the tissue sample is exposed to these antibodies, and a color reaction is induced, the presence of CD8 can be detected under a microscope.
Understanding the presence and location of CD8 in a tissue sample can provide valuable insights for the diagnosis and management of various health conditions. For instance, a high concentration of CD8 T cells in a tumor sample can indicate a more robust immune response to the cancer and might be associated with a better prognosis.
|(IHC - CD8)
|No specific instructions are required before the test.
|Price in Hyderabad
What is the CD8 protein?
The CD8 protein is found on the surface of cytotoxic T cells, a type of white blood cell that can kill cancer cells, cells infected with a virus, or cells that are damaged in other ways.
Why is the IHC - CD8 test performed?
The IHC - CD8 test can help diagnose and monitor certain health conditions, such as autoimmune diseases, infections, and cancers. By revealing the presence and location of CD8 T cells in a tissue sample, the test can provide insights into the immune system's response to these conditions.
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How is the IHC - CD8 test performed?
The IHC - CD8 test is performed on a tissue sample, usually obtained through a biopsy. The sample is first fixed to preserve its structures and then treated with antibodies that bind to the CD8 protein. A color reaction is induced to visualize the binding, and the tissue is examined under a microscope.
What does a positive IHC - CD8 result mean?
A positive result means that CD8 T cells are present in the tissue sample. This can be a normal finding, as these cells are part of the immune system and can be found throughout the body. However, unusually high concentrations of CD8 T cells in certain tissues can indicate an active immune response to an infection, autoimmune disease, or cancer.
What does a negative IHC - CD8 result mean?
A negative result means that no CD8 T cells were detected in the tissue sample. This could indicate that the immune system is not actively responding to a health condition in the sampled tissue, or it could simply be a normal finding, depending on the specific tissue and the individual's overall health.
Are there any risks associated with the IHC - CD8 test?
The risks associated with the IHC - CD8 test are primarily related to the biopsy procedure used to obtain the tissue sample. These risks can include pain, bleeding, infection, and, in rare cases, damage to nearby structures.
What factors can affect the result of the IHC - CD8 test?
Factors that can affect the result of the IHC - CD8 test include the quality of the tissue sample, the specific method used for the test, and the individual's overall health.
Is the IHC - CD8 test the same as a CD8 blood test?
No, the IHC - CD8 test is not the same as a CD8 blood test. The IHC - CD8 test looks for the presence and location of CD8 T cells in a tissue sample, while a CD8 blood test measures the number of CD8 T cells in a blood sample.
Can I eat and drink normally before the IHC - CD8 test?
Yes, you can eat and drink normally before the test. The IHC - CD8 test does not require fasting or any other special preparation.
When can I expect the results of the IHC - CD8 test?
The results of the IHC - CD8 test are typically available within 1-2 days after the test is performed.
What should I do if my IHC - CD8 test results are abnormal?
If your IHC - CD8 test results are abnormal, you should consult with your healthcare provider. They can help you understand what the results mean in the context of your overall health and any symptoms you may be experiencing.
Can the IHC - CD8 test be used to monitor the progress of a disease?
Yes, the IHC - CD8 test can be used to monitor the progress of diseases that involve the immune system. Changes in the presence or location of CD8 T cells in subsequent tissue samples can indicate how a disease is progressing or how well the body is responding to treatment.
Who can order the IHC - CD8 test?
The IHC - CD8 test is typically ordered by a healthcare provider who is managing your care. This could be a primary care physician, an oncologist, an immunologist, or another type of specialist, depending on your health condition.
Is the IHC - CD8 test covered by insurance?
Coverage for the IHC - CD8 test varies by insurance company and policy. You should check with your insurance provider to determine whether this test is covered.
Can the IHC - CD8 test diagnose specific diseases?
The IHC - CD8 test alone does not diagnose specific diseases. However, it can help to provide a more complete picture of the immune system's response to a disease. For instance, in some types of cancer, high levels of CD8 T cells in a tumor can indicate a more robust immune response.
How often should the IHC - CD8 test be performed?
The frequency of the IHC - CD8 test depends on various factors, including your current health, the nature of the disease being monitored, and the guidance of your healthcare provider.
What does it mean if there are high levels of CD8 in a cancer tissue sample?
High levels of CD8 T cells in a cancer tissue sample often indicate an active immune response against the cancer. This can be a positive sign and is often associated with a better prognosis. However, the specifics can vary depending on the type of cancer and individual circumstances.
Can the IHC - CD8 test be used to monitor treatment effectiveness?
Yes, in some cases, the IHC - CD8 test can be used to monitor the effectiveness of treatments like immunotherapy. Changes in the concentration or distribution of CD8 T cells may provide insights into how well the treatment is working.
What is the difference between CD4 and CD8 T cells?
CD4 and CD8 are markers on the surface of T cells, a type of white blood cell. CD4 T cells, often called helper T cells, help orchestrate the immune response by activating other immune cells. CD8 T cells, often called cytotoxic T cells, can directly kill infected or cancerous cells.
What precautions should be taken before the IHC - CD8 test?
There are no specific precautions needed before an IHC - CD8 test. However, you should inform your healthcare provider if you have any allergies, are taking any medications, or have any underlying health conditions.
Immunohistochemistry testing, such as the IHC - CD8 test, provides valuable insights into the workings of the body at the cellular level, especially in relation to the immune response. The test results can aid healthcare providers in understanding a patient's disease and tailoring treatment accordingly. It is always recommended to discuss the necessity, benefits, risks, and implications of the IHC - CD8 test results with your healthcare provider to understand it fully in the context of your health condition.
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